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2021-12-23

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Gilead's Remdesivir Shows Consistent Efficacy In Patients With Comorbidities With Higher Risk for Severe COVID-19

Gilead Sciences Inc announced full results from a Phase 3 study of a three-day course of Veklury (re

Gilead's Remdesivir Shows Consistent Efficacy In Patients With Comorbidities With Higher Risk for Severe COVID-19

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20:09</p>\n</div>\n\n</div>\n\n\n</h4>\n\n</header>\n<article>\n<p><b>Gilead Sciences Inc</b>&nbsp;announced full results&nbsp;from a Phase 3 study of a three-day course of Veklury (remdesivir) non-hospitalized COVID-19 patients at high risk for disease progression.</p>\n<ul>\n <li>Participants receiving Veklury treatment had an 87% reduction in risk for the composite primary endpoint of COVID-19-related hospitalization or all-cause death by Day 28.</li>\n <li>There was an 81% reduction in the risk for the composite secondary endpoint of COVID-19-related medical visits due to COVID-19 or all-cause death by Day 28 compared to placebo.</li>\n <li>There was no difference observed in nasopharyngeal SARS-CoV-2 viral load up to Day 7 between groups, indicating that upper respiratory viral loads do not reliably predict treatment outcomes in COVID-19.</li>\n <li>No deaths were observed in either arm in the study by Day 28.</li>\n <li>The study includes new subgroup analyses which showed 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for disease progression.\n\nParticipants receiving Veklury treatment had an 87% reduction in risk for the composite primary endpoint of COVID-19-related hospitalization or all-cause death by Day 28.\nThere was an 81% reduction in the risk for the composite secondary endpoint of COVID-19-related medical visits due to COVID-19 or all-cause death by Day 28 compared to placebo.\nThere was no difference observed in nasopharyngeal SARS-CoV-2 viral load up to Day 7 between groups, indicating that upper respiratory viral loads do not reliably predict treatment outcomes in COVID-19.\nNo deaths were observed in either arm in the study by Day 28.\nThe study includes new subgroup analyses which showed consistent efficacy of Veklury for patients irrespective of their key risk factors for severe COVID-19.\nParticipants with comorbidities had a reduced risk of COVID-19-related hospitalization by Day 28 with Veklury treatment.\nThe safety profile was similar between Veklury and placebo across the variety of outpatient settings in this trial.\nThe most common treatment-emergent adverse events in patients taking Veklury were nausea and headache.\nPrice Action: GILD shares closed 0.23% at $72.60 during after-hours trading on Wednesday.","news_type":1},"isVote":1,"tweetType":1,"viewCount":1136,"commentLimit":10,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"symbols":[],"verified":2,"subType":0,"readableState":1,"langContent":"CN","currentLanguage":"CN","warmUpFlag":false,"orderFlag":false,"shareable":true,"causeOfNotShareable":"","featuresForAnalytics":[],"commentAndTweetFlag":false,"andRepostAutoSelectedFlag":false,"upFlag":false,"length":4,"xxTargetLangEnum":"ZH_CN"},"commentList":[],"hasMoreComment":false,"orderType":2}

Gilead's Remdesivir Shows Consistent Efficacy In Patients With Comorbidities With Higher Risk for Severe COVID-19

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