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2021-12-22

Valneva Posts Positive Lot-to-Lot Consistency Data For Its Single-Dose Chikungunya Vaccine

Valneva SE announced topline results from the lot-to-lot Phase 3 trial of its single-shot chikunguny

Valneva Posts Positive Lot-to-Lot Consistency Data For Its Single-Dose Chikungunya Vaccine

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It has been designed by deleting a part of the chikungunya virus genome.</li>\n <li><b>Price Action:</b>&nbsp;VLAN shares are closed at $57.39 on Tuesday.</li>\n</ul>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1176786115","content_text":"Valneva SE announced topline results from the lot-to-lot Phase 3 trial of its single-shot chikungunya vaccine candidate, VLA1553.\n\nThe trial met its primary endpoint, demonstrating that three consecutively manufactured vaccine lots elicited equivalent immune responses on Day 29 after vaccination.\nLot-to-lot trials demonstrate manufacturing consistency, one of the standard requirements for vaccine licensure.\nThe trial, which included 408 participants aged 18 to 45 years, confirmed the favorable immunogenicity profile demonstrated in the pivotal Phase 3 trial.\nAll three lots were equally well-tolerated, and the safety profile was consistent with the pivotal Phase 3 trial results.\nThe lot-to-lot data will be part of its submission with the FDA expected to start in 2022.\nThe lot-to-lot trial will continue towards the final six-month analysis, with final trial results expected in Q2 of 2022.\nChikungunya is a mosquito-borne viral disease.\nVLA1553 is a live-attenuated, single-dose vaccine candidate targeting the chikungunya virus. 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Valneva Posts Positive Lot-to-Lot Consistency Data For Its Single-Dose Chikungunya Vaccine

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