Covid-19 Antibody Drugs Are Challenged by Omicron, Preliminary Testing Indicates_老虎社区_美港股上老虎

Covid-19 Antibody Drugs Are Challenged by Omicron, Preliminary Testing Indicates

The Wall Street Journal2021-11-30

Regeneron said its antibody drug cocktail was found to lose effectiveness against the new variant A monoclonal antibody treatment site in Pembroke Pines, Fla., earlier this year. Preliminary tests ...

网页链接

免责声明：本文观点仅代表作者个人观点，不构成本平台的投资建议，本平台不对文章信息准确性、完整性和及时性做出任何保证，亦不对因使用或信赖文章信息引发的任何损失承担责任。

145

HengHuat
·2021-12-01
Current ones no match for the new powerful variant, that is very understandable. Viruses adapt and evolve faster than vaccines
回复
点赞
举报
UNknown
·2021-12-01
Ok Thanks
回复
1
举报
PearlynCSY
·2021-12-01
Yesterday, Moderna CEO says vaccines likely no match for Omicron variant. And that it could take months to develop and ship an omicron specific vaccine, but a higher dose of its booster could be ready much sooner.
回复
2
举报
收起
- KH321:
  OK
  2021-12-01
  回复
  举报
HENRYCSC
·2021-11-30
😅
回复
1
举报
CcccL
·2021-11-30
Confusing. A lot of uncertainty
回复
2
举报
收起
- Tan123:
  not surprised, 50 mutations
  2021-12-01
  回复
  举报
- Anneater:
  Hmm
  2021-11-30
  回复
  举报
Gaga71
·2021-11-30
Complicated!
回复
5
举报
收起
- BettyT:
  Agree
  2021-11-30
  回复
  举报
Andaroo
·2021-11-30
Drugs are bad mmmmkay
回复
4
举报
KCmax
·2021-11-30
Please like, thanks
回复
5
举报
收起
- JeremyKok:
  hi. please like and comment back. thank you.
  2021-12-01
  回复
  举报
- lololol13:
  ok
  2021-11-30
  回复
  举报
- Andaroo:
  like
  2021-11-30
  回复
  举报
RieslingHawk
·2021-11-30
BEAR STRONKKKKK
回复
5
举报
Mattsailor
·2021-11-30
It's going to take some time before we know how bad it will be.
回复
4
举报
AsherA
·2021-11-30
Like pls
回复
6
举报
收起
- JeremyKok:
  hi. please like and comment back. thank you.
  2021-12-01
  回复
  举报
MHh
·2021-11-30
Probably a perpetual cycle to come with future new variants…
回复
7
举报
masran
·2021-11-30
good
回复
6
举报
收起
- AsherA:
  hi
  2021-11-30
  回复
  举报
JoelLee
·2021-11-30
Gogogogogogog
回复
6
举报
Ccv
·2021-11-30
[Speechless]
回复
2
举报
74809e5c
·2021-11-30
👌
回复
4
举报
TSLA玻璃手
·2021-11-30
GG
回复
5
举报
收起
- TSLA玻璃手:
  Yup
  2021-11-30
  回复
  举报
Benzz
·2021-11-30
Ok
回复
6
举报
IZzz
·2021-11-30
K
回复
8
举报
收起
- IZzz:
  K
  2021-12-02
  回复
  举报
- IZzz:
  K
  2021-12-01
  回复
  举报
- Benzz:
  Ok
  2021-11-30
  回复
  举报
Booooooooooo
·2021-11-30
K
回复
6
举报
收起
- Booooooooooo:
  K
  2021-12-10
  回复
  举报
- Booooooooooo:
  K
  2021-12-09
  回复
  举报
- Booooooooooo:
  Ok
  2021-12-08
  回复
  举报
查看更多 2 条评论

热议股票

7x24

全部

关于我们·老虎社区守则·老虎社区账号管理规范·老虎社区服务协议·老虎社区隐私政策

公司名称：北京至简风宜信息技术有限公司

违法和不良信息投诉：010-5681-3562（工作时间9:30-18:30）

邮箱：service@laohu8.com

营业执照：91110105MA01A4U55R

ICP备：京ICP备18016422号

网安备：京公网安备11010502036490

关注我们

{"i18n":{"language":"zh_CN"},"data":{"share":"https://www.laohu8.com/m/news/1192203085?lang=zh_CN&edition=full","thumbnail":"","is_english":true,"pubTime":"2021-11-30 19:59","share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","id":"1192203085","market":"us","top_or_hot":-1,"title":"Covid-19 Antibody Drugs Are Challenged by Omicron, Preliminary Testing Indicates","media":"The Wall Street Journal","content":"<div>\n<p>Regeneron said its antibody drug cocktail was found to lose effectiveness against the new variant\nA monoclonal antibody treatment site in Pembroke Pines, Fla., earlier this year.\nPreliminary tests ...</p>\n\n<a href=\"https://www.wsj.com/articles/covid-19-antibody-drugs-are-challenged-by-omicron-preliminary-testing-indicates-11638270003?mod=Searchresults_pos1&page=1\">网页链接</a>\n\n</div>\n","source":null,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Covid-19 Antibody Drugs Are Challenged by Omicron, Preliminary Testing Indicates</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nCovid-19 Antibody Drugs Are Challenged by Omicron, Preliminary Testing Indicates\n</h2>\n\n<h4 class=\"meta\">\n\n\n2021-11-30 19:59 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://www.wsj.com/articles/covid-19-antibody-drugs-are-challenged-by-omicron-preliminary-testing-indicates-11638270003?mod=Searchresults_pos1&page=1><strong>The Wall Street Journal</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>Regeneron said its antibody drug cocktail was found to lose effectiveness against the new variant\nA monoclonal antibody treatment site in Pembroke Pines, Fla., earlier this year.\nPreliminary tests ...</p>\n\n<a href=\"https://www.wsj.com/articles/covid-19-antibody-drugs-are-challenged-by-omicron-preliminary-testing-indicates-11638270003?mod=Searchresults_pos1&page=1\">网页链接</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"LLY","symbol_name":"礼来","start_time":0,"source_url":"https://www.wsj.com/articles/covid-19-antibody-drugs-are-challenged-by-omicron-preliminary-testing-indicates-11638270003?mod=Searchresults_pos1&page=1","article_id":"1192203085","we_media_id":null,"thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=1192203085","pubTimestamp":1638273550,"sourceInfo":null,"weMediaInfo":null,"summary":"Regeneron said its antibody drug cocktail was found to lose effectiveness against the new variant\nA ","collect":0,"end_time":0,"defaultTopTitle":"wsj.com","property":[],"viewcount":null,"language":"en","relate_stocks":{"LLY":"礼来","REGN":"再生元制药公司"},"translate_title":"初步测试表明，新冠肺炎抗体药物受到奥米克隆的挑战","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"LLY":0.9,"REGN":0.9},"content_text":"Regeneron said its antibody drug cocktail was found to lose effectiveness against the new variant\nA monoclonal antibody treatment site in Pembroke Pines, Fla., earlier this year.\nPreliminary tests indicate the Covid-19 antibody drug cocktail from Regeneron Pharmaceuticals Inc. loses effectiveness against Omicron, the company said Tuesday, a sign that some products in an important class of therapies might need modifying if the new strain becomes widespread.\nSeparate testing of another authorized Covid-19 antibody drug cocktail, from Eli Lilly& Co., indicates it also isn’t as effective against Omicron, outside scientists said. Lilly said it is testing the new variant against its antibody treatment and wouldn’t speculate on what the results will be.\nThe findings are the early results of researchers’ race to assess the impact of the new Omicron variant on Covid-19 treatments that patients, doctors and hospitals have been relying on, as well as pills in development that have promised to keep people out of the hospital.\nResearchers say some antibody therapies are likely to be especially vulnerable to Omicron because it contains mutations to the spike protein that the Regeneron and Lilly drugs target, while other drugs should hold up well because they attack elements of the virus unchanged in the variant.\nMonoclonal antibodies are lab-made molecules derived from survivors of Covid-19 or mice engineered to have human immune systems. When given soon after infection, the drugs attach to the surface of the coronavirus and prevent it from replicating itself in new cells.\nThey are the only drugs authorized to treat patients, before they require hospitalization, who are at high risk of developing severe cases.\nThe drugs differ from vaccines, which train the immune system how to defend against the virus, including with the production of antibodies. Last year, former President Donald Trump credited Regeneron’s drug with his speedy recovery from Covid-19.\nRegeneron said it would be able to quantify the impact of the variant in coming weeks, after further testing is done.\nAntiviral pills such as Pfizer’s Paxlovid appear to be unaffected by the variant.\nIf final testing shows that its antibody drugs are less effective against Omicron, Regeneron has developed alternative antibodies that it can push into clinical testing and that it thinks will retain effectiveness against the variant, said George Yancopoulos, the company’s president and chief scientific officer.\nOne of Regeneron’s alternative antibodies is already in clinical testing, which the company began in anticipation of new variants emerging over time.\nThe Omicron variant was identified last week by scientists in South Africa, prompting drug researchers to scramble to see if the relatively small medicine chest of Covid-19 treatments would still work against the new strain if it ends up spreading widely.\n“What we have to admit is, in the course of the past six days, our urgency has increased,” Dr. Yancopoulos said in an interview. “What started out as a backup plan has now been made a lot more urgent.”\nScientists at the Fred Hutchinson Cancer Research Center in Seattle found that individual mutations from Omicron reduced or eliminated the ability of Regeneron’s and Lilly’s drugs to attach to the virus, said Allie Greaney, a Ph.D. candidate at the center and the University of Washington in Seattle.\nMore comprehensive tests of the drugs against the entire variant are needed to fully understand the impact, she said. “I’m not certain what the exact magnitude of effect would be, but probably less effective,” said Ms. Greaney.\nLilly is in the process of testing the new variant against its drug, a combination of two antibodies called bamlanivimab and etesevimab,said Nicole Kallewaard, a Lilly virologist and research adviser.\nShe declined to comment on the results showing reduced effectiveness against individual Omicron mutations, because the results may differ when all of the mutations are combined.\n“I think that we need to wait for confirmation of the whole virus,” said Dr. Kallewaard. “Hopefully, the data will come in the next few weeks.”\nA rise in the prevalence of Omicron could present an opportunity for competitors who say their drugs don’t appear in preliminary testing to be affected by the variant, including Vir Biotechnology Inc. and GlaxoSmithKline PLC, whose drug sotrovimab was authorized for emergency use earlier this year.\nFred Hutchinson researchers also said their initial testing indicated the Vir-GSK antibody drug retained its effectiveness.\nAdagio Therapeutics Inc.,a biotech with a Covid-19 antibody drug in clinical trials, said its antibody also appears to be unaffected by the new variant.\nVir, Glaxo and Adagio said they are conducting further tests to confirm that their drugs aren’t affected by Omicron.\nOmicron poses a threat to lab-made antibody drugs as well as antibodies generated by vaccines, because the new variant has mutations on the spike protein part of the virus where antibodies are known to frequently attach themselves, scientists say.\nVir and Adagio officials said the companies designed their antibodies with the aim of targeting spots on the virus that are common across different coronaviruses that remained stable even after numerous mutations over many years.\n“They bind to a region of the virus that through decades of evolution has not changed a lot,” Adagio Chief Executive Tillman Gerngross said in an interview. “Those conserved areas make the virus much more vulnerable” to antibodies.\nIt will take at least two weeks to create a version of the full Omicron virus variant and test antibody drugs against it, company officials said. Still, scientists say they are concerned by what they know already about the variant’s ability to evade antibodies produced by vaccines, prior infection or from drug treatment.\n“Omicron hasn’t become the next Delta,” Vir Chief Scientific Officer Skip Virgin said in an interview. But “we think the extent of the mutations, the number of them, means that the world needs to take Omicron very seriously.”\nAntiviral drugs, including pills from Merck& Co. and partner Ridgeback Biotherapeutics LP and from Pfizer Inc. that are being evaluated for authorization,appear to be unaffected by the variant because they target a different site on the virus, said Michel Nussenzweig, an immunologist at Rockefeller University.\nDoctors and patients have been looking forward to authorization of the pills, which in clinical trials have reduced the risk of hospitalization if taken early enough.\n“The targets of the pills appear to be under less pressure and may be OK, but this too needs to be tested,” said Dr. Nussenzweig.\nPfizer and Merck said they expect their drugs to be effective against Omicron.\nGilead SciencesInc. also said it expects Veklury, its antiviral drug used to treat hospitalized patients, to retain effectiveness against Omicron as it has against other variants of concern.","kind":null,"is_publish_news":true,"is_publish_highlight":true,"is_publish_live":null,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1},"commentList":[{"id":609743052,"gmtCreate":1638331500362,"gmtModify":1638331500479,"author":{"id":"4089527924629590","authorId":"4089527924629590","name":"HengHuat","avatar":"https://static.tigerbbs.com/5854d1323f59ffe9e66dca6d58fd6af8","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"Current ones no match for the new powerful variant, that is very understandable. Viruses adapt and evolve faster than vaccines","listText":"Current ones no match for the new powerful variant, that is very understandable. Viruses adapt and evolve faster than vaccines","text":"Current ones no match for the new powerful variant, that is very understandable. Viruses adapt and evolve faster than vaccines","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609743052","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609544749,"gmtCreate":1638314157014,"gmtModify":1638314157014,"author":{"id":"4093776015978190","authorId":"4093776015978190","name":"UNknown","avatar":"https://static.tigerbbs.com/544ab1c11c2e3063efc979d573c9bf0f","vip":1,"crmLevel":5,"crmLevelSwitch":0},"htmlText":"Ok&nbsp;Thanks&nbsp;","listText":"Ok&nbsp;Thanks&nbsp;","text":"Ok Thanks","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609544749","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609553442,"gmtCreate":1638312578914,"gmtModify":1638312581350,"author":{"id":"4092458811577680","authorId":"4092458811577680","name":"PearlynCSY","avatar":"https://static.tigerbbs.com/b3e9fe7af061efe80a756d23de62e7b3","vip":1,"crmLevel":4,"crmLevelSwitch":0},"htmlText":"Yesterday, Moderna CEO says vaccines likely no match for Omicron variant. And that it could take months to develop and ship an omicron specific vaccine, but a higher dose of its booster could be ready much sooner.","listText":"Yesterday, Moderna CEO says vaccines likely no match for Omicron variant. And that it could take months to develop and ship an omicron specific vaccine, but a higher dose of its booster could be ready much sooner.","text":"Yesterday, Moderna CEO says vaccines likely no match for Omicron variant. And that it could take months to develop and ship an omicron specific vaccine, but a higher dose of its booster could be ready much sooner.","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":2,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/609553442","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6793082,"gmtCreate":1638321935596,"gmtModify":1638321935626,"authorId":3586451610703869,"author":{"id":3586451610703869,"authorId":3586451610703869,"name":"KH321","avatar":"https://static.tigerbbs.com/c1bb8bd7d6d5df5f9732871fe60999ea","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609553442,"type":1,"supId":0,"prevId":0,"content":"OK","text":"OK","html":"OK"}],"langContent":"CN"},{"id":609211870,"gmtCreate":1638285364185,"gmtModify":1638285364511,"author":{"id":"3575091428590185","authorId":"3575091428590185","name":"HENRYCSC","avatar":"https://static.tigerbbs.com/6d47a6dec25b21dc547a5b982674c499","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"😅","listText":"😅","text":"😅","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609211870","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609688107,"gmtCreate":1638279096921,"gmtModify":1638279097066,"author":{"id":"3566877420609993","authorId":"3566877420609993","name":"CcccL","avatar":"https://static.tigerbbs.com/27eb54773a8f0b3851def7cabc15cb0e","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"Confusing. A lot of uncertainty&nbsp;","listText":"Confusing. A lot of uncertainty&nbsp;","text":"Confusing. A lot of uncertainty","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":2,"commentSize":2,"repostSize":0,"link":"https://laohu8.com/post/609688107","repostId":1192203085,"repostType":2,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6788312,"gmtCreate":1638292645912,"gmtModify":1638292645944,"authorId":3575263084566569,"author":{"id":3575263084566569,"authorId":3575263084566569,"name":"Tan123","avatar":"https://static.tigerbbs.com/f62a61b3de783a68b73436f05185453a","vip":1,"crmLevel":1,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609688107,"type":1,"supId":6785631,"prevId":0,"content":"not surprised,&nbsp; 50 mutations","text":"not surprised,&nbsp; 50 mutations","html":"not surprised,&nbsp; 50 mutations"},{"id":6785631,"gmtCreate":1638280298950,"gmtModify":1638280298980,"authorId":3581571807225162,"author":{"id":3581571807225162,"authorId":3581571807225162,"name":"Anneater","avatar":"https://static.tigerbbs.com/dd99ef969b35027be1194d21c5482e54","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609688107,"type":1,"supId":0,"prevId":0,"content":"Hmm","text":"Hmm","html":"Hmm"}],"langContent":"CN"},{"id":609610972,"gmtCreate":1638277417004,"gmtModify":1638277417809,"author":{"id":"3579082097230100","authorId":"3579082097230100","name":"Gaga71","avatar":"https://static.tigerbbs.com/02afa88b95dc30f4a60767c18f9e2f39","vip":1,"crmLevel":6,"crmLevelSwitch":0},"htmlText":"Complicated!","listText":"Complicated!","text":"Complicated!","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/609610972","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6786369,"gmtCreate":1638283381042,"gmtModify":1638283381070,"authorId":3580536610076415,"author":{"id":3580536610076415,"authorId":3580536610076415,"name":"BettyT","avatar":"https://static.tigerbbs.com/6a4dfe2f455acd2af7629f83ce30e20c","vip":1,"crmLevel":4,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609610972,"type":1,"supId":0,"prevId":0,"content":"Agree","text":"Agree","html":"Agree"}],"langContent":"CN"},{"id":609639372,"gmtCreate":1638276200589,"gmtModify":1638291365853,"author":{"id":"3575199303759784","authorId":"3575199303759784","name":"Andaroo","avatar":"https://static.tigerbbs.com/634c9b9f18158d4a4e497249bdbe8fd5","vip":1,"crmLevel":3,"crmLevelSwitch":0},"htmlText":"Drugs are bad mmmmkay","listText":"Drugs are bad mmmmkay","text":"Drugs are bad mmmmkay","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":4,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609639372","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609694359,"gmtCreate":1638275659492,"gmtModify":1638275659636,"author":{"id":"4088005490387040","authorId":"4088005490387040","name":"KCmax","avatar":"https://static.tigerbbs.com/45501c3f0f17a005aaae037440a22212","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"Please like, thanks","listText":"Please like, thanks","text":"Please like, thanks","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":3,"repostSize":0,"link":"https://laohu8.com/post/609694359","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6790224,"gmtCreate":1638314747879,"gmtModify":1638314747910,"authorId":3567307840510045,"author":{"id":3567307840510045,"authorId":3567307840510045,"name":"JeremyKok","avatar":"https://static.tigerbbs.com/01b03a485f83b6b2615fad8ac9b87bf4","vip":1,"crmLevel":5,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609694359,"type":1,"supId":0,"prevId":0,"content":"hi. please like and comment back. thank you.","text":"hi. please like and comment back. thank you.","html":"hi. please like and comment back. thank you."},{"id":6784902,"gmtCreate":1638276496143,"gmtModify":1638276496241,"authorId":3583916713249739,"author":{"id":3583916713249739,"authorId":3583916713249739,"name":"lololol13","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":3,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609694359,"type":1,"supId":0,"prevId":0,"content":"<u>ok</u>","text":"<u>ok</u>","html":"<u>ok</u>"},{"id":6784843,"gmtCreate":1638276206261,"gmtModify":1638276206356,"authorId":3575199303759784,"author":{"id":3575199303759784,"authorId":3575199303759784,"name":"Andaroo","avatar":"https://static.tigerbbs.com/634c9b9f18158d4a4e497249bdbe8fd5","vip":1,"crmLevel":3,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609694359,"type":1,"supId":0,"prevId":0,"content":"<u>like</u>","text":"<u>like</u>","html":"<u>like</u>"}],"langContent":"CN"},{"id":609698823,"gmtCreate":1638275145699,"gmtModify":1638275145699,"author":{"id":"3578973717832794","authorId":"3578973717832794","name":"RieslingHawk","avatar":"https://static.tigerbbs.com/a5390eacc9599c6447d4c42f983fcc76","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"BEAR STRONKKKKK&nbsp;","listText":"BEAR STRONKKKKK&nbsp;","text":"BEAR STRONKKKKK","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609698823","repostId":1192203085,"repostType":2,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609693475,"gmtCreate":1638274892283,"gmtModify":1638274892283,"author":{"id":"3585191808723701","authorId":"3585191808723701","name":"Mattsailor","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":8,"crmLevelSwitch":0},"htmlText":"It's going to take some time before we know how bad it will be.","listText":"It's going to take some time before we know how bad it will be.","text":"It's going to take some time before we know how bad it will be.","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":4,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609693475","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609699326,"gmtCreate":1638274477682,"gmtModify":1638274477900,"author":{"id":"3581899667853665","authorId":"3581899667853665","name":"AsherA","avatar":"https://static.tigerbbs.com/2302a91d58b23f78216a0958dfecfcf6","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"Like pls","listText":"Like pls","text":"Like pls","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/609699326","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6790228,"gmtCreate":1638314767003,"gmtModify":1638314767033,"authorId":3567307840510045,"author":{"id":3567307840510045,"authorId":3567307840510045,"name":"JeremyKok","avatar":"https://static.tigerbbs.com/01b03a485f83b6b2615fad8ac9b87bf4","vip":1,"crmLevel":5,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609699326,"type":1,"supId":0,"prevId":0,"content":"hi. please like and comment back. thank you.","text":"hi. please like and comment back. thank you.","html":"hi. please like and comment back. thank you."}],"langContent":"CN"},{"id":609690873,"gmtCreate":1638274308801,"gmtModify":1638276233849,"author":{"id":"4091758936365950","authorId":"4091758936365950","name":"MHh","avatar":"https://static.tigerbbs.com/54b2feced9ef5dcc9e95997d1f4db280","vip":1,"crmLevel":6,"crmLevelSwitch":0},"htmlText":"Probably a perpetual cycle to come with future new variants…","listText":"Probably a perpetual cycle to come with future new variants…","text":"Probably a perpetual cycle to come with future new variants…","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":7,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609690873","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609690307,"gmtCreate":1638274281322,"gmtModify":1638274281408,"author":{"id":"3582888796077977","authorId":"3582888796077977","name":"masran","avatar":"https://static.tigerbbs.com/5258de17f60ac17503ecfa2ededa974d","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"good","listText":"good","text":"good","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/609690307","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6784576,"gmtCreate":1638274481563,"gmtModify":1638274481598,"authorId":3581899667853665,"author":{"id":3581899667853665,"authorId":3581899667853665,"name":"AsherA","avatar":"https://static.tigerbbs.com/2302a91d58b23f78216a0958dfecfcf6","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609690307,"type":1,"supId":0,"prevId":0,"content":"<u>hi</u>","text":"<u>hi</u>","html":"<u>hi</u>"}],"langContent":"CN"},{"id":609607675,"gmtCreate":1638274229989,"gmtModify":1638274230538,"author":{"id":"3579882572140125","authorId":"3579882572140125","name":"JoelLee","avatar":"https://static.tigerbbs.com/e1f6c92b13d94cba61906c07dbbb2ab6","vip":1,"crmLevel":1,"crmLevelSwitch":0},"htmlText":"Gogogogogogog","listText":"Gogogogogogog","text":"Gogogogogogog","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609607675","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609607378,"gmtCreate":1638274104798,"gmtModify":1638276247525,"author":{"id":"3585090180578228","authorId":"3585090180578228","name":"Ccv","avatar":"https://static.tigerbbs.com/0ca1b8e7af012d22a61c8b2d7ff7fc3f","vip":1,"crmLevel":5,"crmLevelSwitch":0},"htmlText":"[Speechless]&nbsp;","listText":"[Speechless]&nbsp;","text":"[Speechless]","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":2,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609607378","repostId":1192203085,"repostType":2,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609607987,"gmtCreate":1638274104460,"gmtModify":1638274104603,"author":{"id":"4087514122562540","authorId":"4087514122562540","name":"74809e5c","avatar":"https://community-static.tradeup.com/news/default-avatar.jpg","vip":1,"crmLevel":1,"crmLevelSwitch":0},"htmlText":"👌","listText":"👌","text":"👌","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":4,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609607987","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609607029,"gmtCreate":1638274097989,"gmtModify":1638274098357,"author":{"id":"3575408338074495","authorId":"3575408338074495","name":"TSLA玻璃手","avatar":"https://static.tigerbbs.com/74a100f6cd29713d58bf0f4b64f32143","vip":1,"crmLevel":7,"crmLevelSwitch":0},"htmlText":"GG","listText":"GG","text":"GG","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/609607029","repostId":1192203085,"repostType":2,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6784512,"gmtCreate":1638274104643,"gmtModify":1638274104730,"authorId":3575408338074495,"author":{"id":3575408338074495,"authorId":3575408338074495,"name":"TSLA玻璃手","avatar":"https://static.tigerbbs.com/74a100f6cd29713d58bf0f4b64f32143","vip":1,"crmLevel":7,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609607029,"type":1,"supId":0,"prevId":0,"content":"Yup","text":"Yup","html":"Yup"}],"langContent":"CN"},{"id":609604295,"gmtCreate":1638274074943,"gmtModify":1638274075430,"author":{"id":"3570593382729221","authorId":"3570593382729221","name":"Benzz","avatar":"https://static.tigerbbs.com/05492ca80eadb47ced7a52ab97d09507","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"Ok","listText":"Ok","text":"Ok","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/609604295","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":609604692,"gmtCreate":1638274059501,"gmtModify":1638274059598,"author":{"id":"3581583942020074","authorId":"3581583942020074","name":"IZzz","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":2,"crmLevelSwitch":0},"htmlText":"K","listText":"K","text":"K","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":8,"commentSize":3,"repostSize":0,"link":"https://laohu8.com/post/609604692","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6810141,"gmtCreate":1638417563690,"gmtModify":1638417563806,"authorId":3581583942020074,"author":{"id":3581583942020074,"authorId":3581583942020074,"name":"IZzz","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609604692,"type":1,"supId":6784507,"prevId":0,"content":"K","text":"K","html":"K"},{"id":6795334,"gmtCreate":1638333299905,"gmtModify":1638333299938,"authorId":3581583942020074,"author":{"id":3581583942020074,"authorId":3581583942020074,"name":"IZzz","avatar":"https://static.laohu8.com/default-avatar.jpg","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609604692,"type":1,"supId":6784507,"prevId":0,"content":"K","text":"K","html":"K"},{"id":6784507,"gmtCreate":1638274084274,"gmtModify":1638274084373,"authorId":3570593382729221,"author":{"id":3570593382729221,"authorId":3570593382729221,"name":"Benzz","avatar":"https://static.tigerbbs.com/05492ca80eadb47ced7a52ab97d09507","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609604692,"type":1,"supId":0,"prevId":0,"content":"Ok","text":"Ok","html":"Ok"}],"langContent":"CN"},{"id":609605448,"gmtCreate":1638274000388,"gmtModify":1638274000527,"author":{"id":"3581484916070591","authorId":"3581484916070591","name":"Booooooooooo","avatar":"https://static.tigerbbs.com/77192e7418cc5ae69f989ac4732ad2cb","vip":1,"crmLevel":3,"crmLevelSwitch":0},"htmlText":"K","listText":"K","text":"K","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":9,"repostSize":0,"link":"https://laohu8.com/post/609605448","repostId":1192203085,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":6928684,"gmtCreate":1639145879441,"gmtModify":1639145879468,"authorId":3581484916070591,"author":{"id":3581484916070591,"authorId":3581484916070591,"name":"Booooooooooo","avatar":"https://static.tigerbbs.com/77192e7418cc5ae69f989ac4732ad2cb","vip":1,"crmLevel":3,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609605448,"type":1,"supId":6784509,"prevId":0,"content":"K","text":"K","html":"K"},{"id":6911294,"gmtCreate":1639034634509,"gmtModify":1639034634606,"authorId":3581484916070591,"author":{"id":3581484916070591,"authorId":3581484916070591,"name":"Booooooooooo","avatar":"https://static.tigerbbs.com/77192e7418cc5ae69f989ac4732ad2cb","vip":1,"crmLevel":3,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609605448,"type":1,"supId":6784509,"prevId":0,"content":"K","text":"K","html":"K"},{"id":6896067,"gmtCreate":1638943460698,"gmtModify":1638943460728,"authorId":3581484916070591,"author":{"id":3581484916070591,"authorId":3581484916070591,"name":"Booooooooooo","avatar":"https://static.tigerbbs.com/77192e7418cc5ae69f989ac4732ad2cb","vip":1,"crmLevel":3,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609605448,"type":1,"supId":6784509,"prevId":0,"content":"Ok","text":"Ok","html":"Ok"},{"id":6864879,"gmtCreate":1638764766734,"gmtModify":1638764766834,"authorId":3581484916070591,"author":{"id":3581484916070591,"authorId":3581484916070591,"name":"Booooooooooo","avatar":"https://static.tigerbbs.com/77192e7418cc5ae69f989ac4732ad2cb","vip":1,"crmLevel":3,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609605448,"type":1,"supId":6784509,"prevId":0,"content":"K","text":"K","html":"K"},{"id":6848551,"gmtCreate":1638661981478,"gmtModify":1638661981505,"authorId":3581484916070591,"author":{"id":3581484916070591,"authorId":3581484916070591,"name":"Booooooooooo","avatar":"https://static.tigerbbs.com/77192e7418cc5ae69f989ac4732ad2cb","vip":1,"crmLevel":3,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":609605448,"type":1,"supId":6784509,"prevId":0,"content":"K","text":"K","html":"K"}],"langContent":"CN"}],"hasMoreComments":true,"newsSizeData":{"likeSize":145,"commentSize":20,"repostSize":0,"favoriteSize":2,"likeStatus":false,"favoriteStatus":false}}