• 163
  • 30
  • 1

BioNTech SE stock jumped 4% in morning trading

Tiger Newspress2021-09-15

BioNTech SE stock jumped 4% in morning trading as Pfizer said booster shots of vaccine restore waning Immunity.Pfizer shares rose 0.7%.

Pfizer Inc. said that data from the U.S. and Israel suggest that the efficacy of its Covid-19 vaccine wanes over time, and that a booster dose was safe and effective at warding off the virus and new variants.

The company detailed the data in a presentation it will deliver to a meeting of outside advisers to the Food and Drug Administration on Friday. The panel is expected to make recommendations for whether more Americans should receive booster shots.

“Real-world data from Israel and the United States suggest that rates of breakthrough infections are rising faster in individuals who were vaccinated earlier,” Pfizer said in its presentation, which was posted on the FDA website. The drug giant is partnering with Germany’s BioNTech SE to make the shots.

The decrease in effectiveness is “primarily due to waning of vaccine immune responses over time,” rather than the delta variant, Pfizer researchers said in the presentation.

Unpublished Data

According to a meeting agenda the FDA posted on its website, in addition to the Pfizer presentation, the Friday panel will include presentations from the Centers for Disease Control and Prevention, FDA staff and researchers from Israel and the U.K.

The Israel officials will present data from that country on booster protection against infections and severe disease, according to the agenda, and a professor of medical statistics from the University of Bristol will present data on real-world vaccine effectiveness.

While its vaccine continues to provide strong protection against hospitalizations and severe disease in the U.S., Pfizer said, data from Israel and elsewhere suggests that reduction in efficacy against infection may be followed by reduced effectiveness against severe disease, especially among vulnerable elderly people.

Early unpublished data from an Israeli health maintenance organization suggest that a third booster dose is highly effective in areas where the delta variant is dominant, according to the Pfizer document. Giving a third dose to people more than 60 years old was associated with 86% effectiveness against testing positive for Covid starting at least a week after the booster, Pfizer said.

Pfizer also detailed immune response results from a final-stage trial of booster shots in over 300 people, showing that a third dose bolstered blood antibody levels. One month after the third dose, levels of the protective antibodies were more than triple what they had been a month after the second shot.

No new unexpected side effects were identified from safety data associated with boosters in the final-stage study, according to the Pfizer report. Consideration of a booster dose six months after a second dose of its shot is warranted, based on similarities between the outbreaks in Israel and the U.S., Pfizer said.

Signs of Friction

Marion Gruber, one of two top vaccine officials who FDA recently said will step down later this year, is also scheduled to speak. Gruber was co-author of an article in The Lancet earlier this week arguing that booster shots weren’t yet necessary for most people. The departures of the two longtime agency staff are a potential sign of friction over the Biden booster plan.

The FDA hasn’t yet posted its staff report on the booster data. The agency’s documents are typically released 48 hours before the start of a panel meeting.

The FDA is working as quickly as possible to post the items throughout the day as they are finalized and available, spokesperson Alison Hunt said.

免责声明:本文观点仅代表作者个人观点,不构成本平台的投资建议,本平台不对文章信息准确性、完整性和及时性做出任何保证,亦不对因使用或信赖文章信息引发的任何损失承担责任。

举报

评论30

  • WenxinLee
    ·2021-09-21
    Nice
    回复
    举报
  • Jac_jk
    ·2021-09-17
    With countries opening up and giving up any potential lock down measures, getting booster shot sound like a longer term solution 
    回复
    举报
  • YCGan
    ·2021-09-16
    Great
    回复
    举报
  • Shlee
    ·2021-09-16
    Nice
    回复
    举报
  • james_l
    ·2021-09-16
    Expected with all the news of the booster shot
    回复
    举报
  • Darianthum
    ·2021-09-16
    Please like 🙏🙏🙏
    回复
    举报
  • GuSen
    ·2021-09-16
    Sounds like a booster shot!
    回复
    举报
  • Imeeng
    ·2021-09-16
    Like
    回复
    举报
  • Kel9670ong
    ·2021-09-16
    Nice nice
    回复
    举报
  • bluem
    ·2021-09-16
    Like
    回复
    举报
  • ahoon
    ·2021-09-16
    Good
    回复
    举报
  • LennartM
    ·2021-09-16
    like please
    回复
    举报
  • Blessy
    ·2021-09-16
    Like thks 
    回复
    举报
    收起
    • LennartM
      done
      2021-09-16
      回复
      举报
  • PhilipGoh
    ·2021-09-16
    Great 👍
    回复
    举报
  • DMC8
    ·2021-09-16
    Nice 
    回复
    举报
    收起
    • Albaakbert
      [Miser][Happy][What]
      2021-09-16
      回复
      举报
  • kcwang4982
    ·2021-09-16
    Okngo 
    回复
    举报
  • Jaja2000
    ·2021-09-16
    Ok
    回复
    举报
  • LohYK
    ·2021-09-16
    Today most biotech stocks went up.... Seems Like a coordinated move
    回复
    举报
  • MunYee531
    ·2021-09-15
    Nice
    回复
    举报
  • HENRYCSC
    ·2021-09-15
    Good 
    回复
    举报
    收起
 
 
 
 

热议股票

 
 
 
 
 

7x24