高瓴等巨头加持！首家“A+H+N”三地上市药企来了_老虎社区_美港股上老虎

高瓴等巨头加持！首家“A+H+N”三地上市药企来了

中国证券报 2021-06-28

6月28日，上交所发布科创板上市委2021年第43次审议会议结果公告，百济神州首发获通过。中金公司及高盛高华为联合保荐人。公司此次科创板IPO拟募资200亿元，用于药物临床试验研发项目、研发中心建设项目、生产基地研发及产业化项目、营销网络建设项目以及补充流动资金。 2016年，百济神州在纳斯达克上市，2018年登陆香港联交所。此次公司科创板IPO获通过，意味着公司成为首家在纳斯达克、港交所与...

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hhyw
·2021-06-29
三地上市，三地圈钱🤔🤔
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健安_1832
·2021-06-29
[龇牙] [龇牙] [龇牙] [龇牙] [龇牙] [龇牙]
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KeithLim0419
·2021-06-29
[微笑]
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Soonsoon
·2021-06-29
[得意]
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1
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- Soonsoon:
  [可爱]
  2021-07-18
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KzvinYBC
·2021-06-29
这就有点厉害了
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1
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- hhyw:
  好
  2021-06-29
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l8698l
·2021-06-29
[微笑]
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温韦
·2021-06-28
[微笑]
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1
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Jas0n96
·2021-06-28
厉害
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小虎小虎小小虎
·2021-06-28
Zan
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- 小虎小虎小小虎:
  Hi
  2021-06-28
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JaniceZhu
·2021-06-28
[得意]
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- JaniceZhu:
  买A股还是要考虑清楚
  2021-06-28
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The first \"A + H + N\" listed pharmaceutical company has come","themeId":null,"isJumpTheme":false,"ttsUrl":"https://static.tigerbbs.com/b585a95de6ecca254c7de80662caf69d","symbols_score_info":{"06160":0.9,"BGNE":0.9},"content_text":"6月28日，上交所发布科创板上市委2021年第43次审议会议结果公告，百济神州首发获通过。中金公司及高盛高华为联合保荐人。\n公司此次科创板IPO拟募资200亿元，用于药物临床试验研发项目、研发中心建设项目、生产基地研发及产业化项目、营销网络建设项目以及补充流动资金。\n2016年，百济神州在纳斯达克上市，2018年登陆香港联交所。此次公司科创板IPO获通过，意味着公司成为首家在纳斯达克、港交所与上交所三地上市的全球性生物科技公司。\n\n来源：上交所网站\n三个核心产品均为国内首创\n百济神州成立于2010年，是一家全球性生物科技公司，专注于研究、开发、生产以及商业化创新型药物。\n目前，公司商业化产品及临床阶段候选药物共有47款，包括8款商业化阶段药物、4款已申报候选药物和35款临床阶段候选药物。3款由百济神州自主研发的创新药物BTK小分子抑制剂百悦泽、抗PD-1单抗百泽安和PARP抑制剂百汇泽处于商业化阶段。\n其中，百悦泽于2019年11月获得美国食品和药品监督管理局（FDA）加速批准上市，成为我国首个在美获批上市的中国本土自主研发抗癌新药，改写了中国抗癌新药“只进不出”的历史，实现国产新药出海“零的突破”，也是首个获得FDA授予四项特殊通道认定的中国新药和首个获得中国CSCO指南与美国NCCN临床指南双重推荐的本土研发抗肿瘤新药。2020年12月，百悦泽获批的两个适应症全部纳入国家新版医保目录。目前，百悦泽已经在美国、中国、阿联酋、加拿大获批上市，并已在全球提交超过20项上市申请，覆盖全球超过40个国家/地区。\n百泽安已在国内获批用于治疗复发或难治性经典型霍奇金淋巴瘤（R/R cHL）、局部晚期或转移性尿路上皮癌（UC）、一线鳞状非小细胞肺癌，前两项适应症已于2020年12月纳入国家新版医保目录。2021年，百济神州与诺华公司就百泽安在北美、欧洲、日本等多个国家的开发与商业化达成授权合作协议，总交易金额超过22亿美元，创下当时国内单品种药物授权交易金额最高纪录，加速推动百泽安走向全球。\n百汇泽是百济神州自主研发的一款PARP1和PARP2抑制剂，是目前已知唯一非药物泵P-gp(P糖蛋白)底物的PARP抑制剂，具有低耐药、高透膜和高捕获性的产品特点。2021年5月，获得国家药监局附条件批准用于治疗既往接受过至少二线化疗、伴有胚系BRCA突变的晚期卵巢癌、输卵管癌或原发性腹膜癌患者，成为中国首款获批用于治疗涵盖铂敏感以及铂耐药复发性伴有胚系BRCA突变的卵巢癌患者PARP抑制剂，也是百济神州第三款获得上市许可的自主研发抗癌新药。\n新药研发、生产、商业化是一个投资大、周期长、风险高的过程，公司在药物早期发现、临床前研究、临床开发、监管审查、生产、商业化推广等多个环节持续投入。\n招股书显示，2017年至2020年1-9月（报告期），百济神州营业收入分别为16.11亿元、13.10亿元、29.54亿元和14.59亿元，包括药品销售收入以及技术授权和研发服务收入，公司实现归属于母公司股东的净利润分别为-9.82亿元、-47.47亿元、-69.15亿元及-81.04亿元。截至2020年9月30日，公司累计未分配利润为-243.03亿元。\n值得注意的是，据公司5月7日发布的业绩报显示，2021年一季度，公司实现收入6.06亿美元，实现净利润0.67亿美元。这也是公司自2018年8月8日港股上市以来，首度在报表中实现盈利。\n逾百项全球临床试验进行中\n报告期，公司的研发费用分别为20.167亿元、45.97亿元、65.88亿元和66.03亿元，研发费用率分别为125.20%、350.88%、223.03%和452.66%。\n公司拥有完整的肿瘤生物学研发体系，建立了包括药物化学、发现生物学、生物药和转换科学在内的临床前研究部门，拥有包括化合物筛选平台、小分子激酶抑制剂优化平台、分析化学研究平台、双（多）特异性抗体发现平台、单B细胞抗体筛选平台和抗体-药物偶联物（ADC）开发平台等多种药物发现技术平台。\n公司的研发引擎与生产和临床开发无缝衔接，源源不断地提供新的产品管线。截至2021年1月，公司共拥有研发人员超过2100名，占员工总数超过40%。同时，公司建立了强大的全球临床开发团队。\n截至2021年3月，公司在超过35个国家和地区执行超过100项计划中或正在进行的临床试验，包括超过25项III期或潜在注册可用的临床试验，总入组患者及健康受试者超过12000人，其中海外入组超过5700人。此外，公司分别于2017、2019和2021年与全球领先的制药和生物科技公司百时美施贵宝、安进和诺华达成了全球战略合作。\n安进、高瓴是重要股东\n截至2020年9月30日，公司第一大股东安进持股比例为20.36%。报告期内，公司股权较为分散，公司任何单一股东所持股权或表决权均未超过30%，且直接持有公司5%以上股份的主要股东之间不存在一致行动关系。因此，公司无控股股东和实际控制人。\n天眼查显示，公司在此次IPO之前，已经完成了9轮融资，高瓴资本参与了多次。\n\n来源：天眼查\n招股说明书显示，截至2020年9月30日，高瓴资本及其一致行动人合计共持有公司1.47亿股，占公司已发行股份总数的12.43%。\n\n来源：公司招股说明书","kind":"news","is_publish_news":true,"is_publish_highlight":true,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1},"commentList":[{"id":150554868,"gmtCreate":1624922710154,"gmtModify":1633947088693,"author":{"id":"3561544476596136","authorId":"3561544476596136","name":"hhyw","avatar":"https://static.tigerbbs.com/62f8a12108672917c80685184f331b6f","vip":1,"crmLevel":4,"crmLevelSwitch":0,"idStr":"3561544476596136","authorIdStr":"3561544476596136"},"htmlText":"三地上市，三地圈钱🤔🤔","listText":"三地上市，三地圈钱🤔🤔","text":"三地上市，三地圈钱🤔🤔","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/150554868","repostId":1138719779,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"langContent":"CN"},{"id":150563618,"gmtCreate":1624922028234,"gmtModify":1633947113878,"author":{"id":"3553346853986978","authorId":"3553346853986978","name":"健安_1832","avatar":"https://static.tigerbbs.com/1a310972d59b708bb82abef5c003c84e","vip":1,"crmLevel":2,"crmLevelSwitch":0,"idStr":"3553346853986978","authorIdStr":"3553346853986978"},"htmlText":"[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;","listText":"[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;","text":"[龇牙] 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