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2021-12-23

$Allakos Inc.(ALLK)$is the company still operating ? overreact !

2021-12-23

overreact..

Allakos slumps 87%, draws analysts downgrade on 'disappointing' lirentelimab data

2021-12-10

reason ?

AMC Stock dipped more than 6% in morning trading

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overreact !","listText":"<a href=\"https://laohu8.com/S/ALLK\">$Allakos Inc.(ALLK)$</a>is the company still operating ? overreact !","text":"$Allakos Inc.(ALLK)$is the company still operating ? overreact !","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/691219244","isVote":1,"tweetType":1,"viewCount":566,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":691210616,"gmtCreate":1640193889962,"gmtModify":1640193889962,"author":{"id":"4098850726603110","authorId":"4098850726603110","name":"nick name","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":8,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4098850726603110","authorIdStr":"4098850726603110"},"themes":[],"htmlText":"overreact..","listText":"overreact..","text":"overreact..","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/691210616","repostId":"1163953446","repostType":2,"repost":{"id":"1163953446","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1640182473,"share":"https://www.laohu8.com/m/news/1163953446?lang=&edition=full","pubTime":"2021-12-22 22:14","market":"us","language":"en","title":"Allakos slumps 87%, draws analysts downgrade on 'disappointing' lirentelimab data","url":"https://stock-news.laohu8.com/highlight/detail?id=1163953446","media":"Tiger Newspress","summary":"Allakos continues to slide, falls 87.4% premarket following yesterday's announcement that its late-s","content":"<p>Allakos&nbsp;continues to slide,&nbsp;falls 87.4% premarket&nbsp;following yesterday's announcement that its late-stage studies, KRYPTOS and ENIGMA 2failed to achieve statistical significance.</p>\n<p><img src=\"https://static.tigerbbs.com/961eae374dfe4dd479394caaf470012c\" tg-width=\"714\" tg-height=\"590\" width=\"100%\" height=\"auto\"></p>\n<p>The studies met their histologic co-primary endpoints but failed to achieve symptomatic endpoints.</p>\n<p>In ENIGMA, patients treated with lirentelimab achieved a 10.0-point reduction in Total Symptom Score-6 (TSS-6) at weeks 23-24 from baseline (baseline = 29.5) compared to an 11.5-point reduction in the placebo group (baseline = 27.7; p=0.343).</p>\n<p>On the second co-primary endpoint of absolute mean change in patient reported Dysphagia Symptom Questionnaire in KRYPTOS trial, the high-dose group achieved a 17.4-point reduction, the low-dose group achieved an 11.9-point reduction and placebo achieved a 14.6-point reduction.</p>\n<p>Following this disappointing result, several analysts lowered their ratings of the stock and slashed the price targets.</p>\n<p>William Blair downgraded the stock to Market Perform from Outperform.</p>\n<p>Analysts of the firm say, \"while we believe lirentelimab has shown clear evidence of histologic activity against eosinophils and mast cells, the failure to achieve co-primary endpoints of patient reported symptoms in both studies raises questions about whether these histologic improvements can translate into clinical improvements.\"</p>\n<p>With lirentelimab performing worse than placebo, there are clearly questions as to why the clean results in Phase II didn’t translate, the analyst notes.</p>\n<p>Cowen analyst Joseph Thome has also cut the recommendation on Allakos to Market Perform from Outperform without the price target (PT) pending pipeline clarity.</p>\n<p>SVB Leerink analyst Thomas Smith downgraded the stock to Market Perform from Outperform, with PT of $17.</p>\n<p>Barclays analyst Carter Gould lowered the firm's PT on Allakos to $8 from $36 and keeps an Underweight rating. The company's lead asset failed in key Phase 3 studies, Gould tells investors in a research note. He views this as the \"end game\" for lirentelimab.</p>\n<p>Morgan Stanley says Allakos' disappointing data increase&nbsp;eosinophilic gastrointestinal diseases (EGIDs) uncertainty.</p>\n<p>Jefferies analyst Maury Raycroft cut the recommendation on&nbsp;Allakos&nbsp;to Hold from Buy.</p>\n<p>LifeSci Capital analyst Samuel Slutsky downgraded the stock to Market Perform from Outperform.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Allakos slumps 87%, draws analysts downgrade on 'disappointing' lirentelimab data</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nAllakos slumps 87%, draws analysts downgrade on 'disappointing' lirentelimab data\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time\">2021-12-22 22:14</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>Allakos&nbsp;continues to slide,&nbsp;falls 87.4% premarket&nbsp;following yesterday's announcement that its late-stage studies, KRYPTOS and ENIGMA 2failed to achieve statistical significance.</p>\n<p><img src=\"https://static.tigerbbs.com/961eae374dfe4dd479394caaf470012c\" tg-width=\"714\" tg-height=\"590\" width=\"100%\" height=\"auto\"></p>\n<p>The studies met their histologic co-primary endpoints but failed to achieve symptomatic endpoints.</p>\n<p>In ENIGMA, patients treated with lirentelimab achieved a 10.0-point reduction in Total Symptom Score-6 (TSS-6) at weeks 23-24 from baseline (baseline = 29.5) compared to an 11.5-point reduction in the placebo group (baseline = 27.7; p=0.343).</p>\n<p>On the second co-primary endpoint of absolute mean change in patient reported Dysphagia Symptom Questionnaire in KRYPTOS trial, the high-dose group achieved a 17.4-point reduction, the low-dose group achieved an 11.9-point reduction and placebo achieved a 14.6-point reduction.</p>\n<p>Following this disappointing result, several analysts lowered their ratings of the stock and slashed the price targets.</p>\n<p>William Blair downgraded the stock to Market Perform from Outperform.</p>\n<p>Analysts of the firm say, \"while we believe lirentelimab has shown clear evidence of histologic activity against eosinophils and mast cells, the failure to achieve co-primary endpoints of patient reported symptoms in both studies raises questions about whether these histologic improvements can translate into clinical improvements.\"</p>\n<p>With lirentelimab performing worse than placebo, there are clearly questions as to why the clean results in Phase II didn’t translate, the analyst notes.</p>\n<p>Cowen analyst Joseph Thome has also cut the recommendation on Allakos to Market Perform from Outperform without the price target (PT) pending pipeline clarity.</p>\n<p>SVB Leerink analyst Thomas Smith downgraded the stock to Market Perform from Outperform, with PT of $17.</p>\n<p>Barclays analyst Carter Gould lowered the firm's PT on Allakos to $8 from $36 and keeps an Underweight rating. The company's lead asset failed in key Phase 3 studies, Gould tells investors in a research note. He views this as the \"end game\" for lirentelimab.</p>\n<p>Morgan Stanley says Allakos' disappointing data increase&nbsp;eosinophilic gastrointestinal diseases (EGIDs) uncertainty.</p>\n<p>Jefferies analyst Maury Raycroft cut the recommendation on&nbsp;Allakos&nbsp;to Hold from Buy.</p>\n<p>LifeSci Capital analyst Samuel Slutsky downgraded the stock to Market Perform from Outperform.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"ALLK":"Allakos Inc."},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1163953446","content_text":"Allakos continues to slide, falls 87.4% premarket following yesterday's announcement that its late-stage studies, KRYPTOS and ENIGMA 2failed to achieve statistical significance.\n\nThe studies met their histologic co-primary endpoints but failed to achieve symptomatic endpoints.\nIn ENIGMA, patients treated with lirentelimab achieved a 10.0-point reduction in Total Symptom Score-6 (TSS-6) at weeks 23-24 from baseline (baseline = 29.5) compared to an 11.5-point reduction in the placebo group (baseline = 27.7; p=0.343).\nOn the second co-primary endpoint of absolute mean change in patient reported Dysphagia Symptom Questionnaire in KRYPTOS trial, the high-dose group achieved a 17.4-point reduction, the low-dose group achieved an 11.9-point reduction and placebo achieved a 14.6-point reduction.\nFollowing this disappointing result, several analysts lowered their ratings of the stock and slashed the price targets.\nWilliam Blair downgraded the stock to Market Perform from Outperform.\nAnalysts of the firm say, \"while we believe lirentelimab has shown clear evidence of histologic activity against eosinophils and mast cells, the failure to achieve co-primary endpoints of patient reported symptoms in both studies raises questions about whether these histologic improvements can translate into clinical improvements.\"\nWith lirentelimab performing worse than placebo, there are clearly questions as to why the clean results in Phase II didn’t translate, the analyst notes.\nCowen analyst Joseph Thome has also cut the recommendation on Allakos to Market Perform from Outperform without the price target (PT) pending pipeline clarity.\nSVB Leerink analyst Thomas Smith downgraded the stock to Market Perform from Outperform, with PT of $17.\nBarclays analyst Carter Gould lowered the firm's PT on Allakos to $8 from $36 and keeps an Underweight rating. The company's lead asset failed in key Phase 3 studies, Gould tells investors in a research note. He views this as the \"end game\" for lirentelimab.\nMorgan Stanley says Allakos' disappointing data increase eosinophilic gastrointestinal diseases (EGIDs) uncertainty.\nJefferies analyst Maury Raycroft cut the recommendation on Allakos to Hold from Buy.\nLifeSci Capital analyst Samuel Slutsky downgraded the stock to Market Perform from Outperform.","news_type":1},"isVote":1,"tweetType":1,"viewCount":747,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":605846773,"gmtCreate":1639148160346,"gmtModify":1639148161911,"author":{"id":"4098850726603110","authorId":"4098850726603110","name":"nick name","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":8,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4098850726603110","authorIdStr":"4098850726603110"},"themes":[],"htmlText":"reason ?","listText":"reason ?","text":"reason ?","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":2,"repostSize":0,"link":"https://laohu8.com/post/605846773","repostId":"1159401236","repostType":2,"repost":{"id":"1159401236","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1639148053,"share":"https://www.laohu8.com/m/news/1159401236?lang=&edition=full","pubTime":"2021-12-10 22:54","market":"us","language":"en","title":"AMC Stock dipped more than 6% in morning trading","url":"https://stock-news.laohu8.com/highlight/detail?id=1159401236","media":"Tiger Newspress","summary":"AMC Stock dipped more than 6% in morning trading as AMC CEO Adam Aron sold another $9.65m worth of s","content":"<p>AMC Stock dipped more than 6% in morning trading&nbsp;as&nbsp;AMC CEO Adam Aron sold another $9.65m worth of shares</p>\n<p><img src=\"https://static.tigerbbs.com/938e1608b0f5bf6a71276c3ce2c87761\" tg-width=\"840\" tg-height=\"470\" referrerpolicy=\"no-referrer\"></p>\n<p><b>AMC Entertainment Holdings, Inc</b>&nbsp;CEO&nbsp;<b>Adam Aron</b>&nbsp;sold almost $9.65 million worth of shares in the cinema chain earlier this week, according to filings with the U.S. Securities and Exchange Commission.</p>\n<p><b>What Happened:</b>Aron sold 312,500 shares on Dec. 7 and continues to own 95,997 shares in the company.</p>\n<p>AMC insiders have shed more than $70 million in shares this year as the company’s stocks have surged after finding favor with retail investors particularly those on Reddit forum r/WallStreetBets.</p>\n<p>Last month, Aron sold 625,000 shares of AMC, worth $25 million.</p>\n<p>The company’s CFO&nbsp;<b>Sean Goodman</b>&nbsp;sold 18,316 shares for nearly $565,000, according to a separate filing.</p>\n<p><b>Why It Matters:</b>Apart from Aron’s current holdings, there are 2.9 million shares issuable in the future to him based on performance targets,reported&nbsp;Bloomberg.</p>\n<p>Goodman has reportedly sold all his shares in the company but 600,000 shares, subject to continued service or targets, are not included.</p>\n<p>Last month, Aron had said on Twitter that 62.5% of his annual pay is in AMC stock and he sold as it is prudent from the point of view of “estate planning.”</p>\n<p><img src=\"https://static.tigerbbs.com/2e3906f6b3a546270106711a8736d511\" tg-width=\"830\" tg-height=\"524\" referrerpolicy=\"no-referrer\" width=\"100%\" height=\"auto\"></p>\n<p>Across the S&amp;P500, insiders have sold $63.5 billion in shares through November, as per the Wall Street Journal. On Thursday,<b>Tesla Inc</b>&nbsp;CEO&nbsp;<b>Elon Musk</b>&nbsp;sold $963 million worth of the automaker’s stock to&nbsp;fulfill his tax obligations.</p>\n<p>Like Musk, Aron too has found a following on Twitter and is known to frequently&nbsp;reach out to the company’s investors&nbsp;through the social media platform.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>AMC Stock dipped more than 6% in morning trading</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nAMC Stock dipped more than 6% in morning trading\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time\">2021-12-10 22:54</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>AMC Stock dipped more than 6% in morning trading&nbsp;as&nbsp;AMC CEO Adam Aron sold another $9.65m worth of shares</p>\n<p><img src=\"https://static.tigerbbs.com/938e1608b0f5bf6a71276c3ce2c87761\" tg-width=\"840\" tg-height=\"470\" referrerpolicy=\"no-referrer\"></p>\n<p><b>AMC Entertainment Holdings, Inc</b>&nbsp;CEO&nbsp;<b>Adam Aron</b>&nbsp;sold almost $9.65 million worth of shares in the cinema chain earlier this week, according to filings with the U.S. Securities and Exchange Commission.</p>\n<p><b>What Happened:</b>Aron sold 312,500 shares on Dec. 7 and continues to own 95,997 shares in the company.</p>\n<p>AMC insiders have shed more than $70 million in shares this year as the company’s stocks have surged after finding favor with retail investors particularly those on Reddit forum r/WallStreetBets.</p>\n<p>Last month, Aron sold 625,000 shares of AMC, worth $25 million.</p>\n<p>The company’s CFO&nbsp;<b>Sean Goodman</b>&nbsp;sold 18,316 shares for nearly $565,000, according to a separate filing.</p>\n<p><b>Why It Matters:</b>Apart from Aron’s current holdings, there are 2.9 million shares issuable in the future to him based on performance targets,reported&nbsp;Bloomberg.</p>\n<p>Goodman has reportedly sold all his shares in the company but 600,000 shares, subject to continued service or targets, are not included.</p>\n<p>Last month, Aron had said on Twitter that 62.5% of his annual pay is in AMC stock and he sold as it is prudent from the point of view of “estate planning.”</p>\n<p><img src=\"https://static.tigerbbs.com/2e3906f6b3a546270106711a8736d511\" tg-width=\"830\" tg-height=\"524\" referrerpolicy=\"no-referrer\" width=\"100%\" height=\"auto\"></p>\n<p>Across the S&amp;P500, insiders have sold $63.5 billion in shares through November, as per the Wall Street Journal. On Thursday,<b>Tesla Inc</b>&nbsp;CEO&nbsp;<b>Elon Musk</b>&nbsp;sold $963 million worth of the automaker’s stock to&nbsp;fulfill his tax obligations.</p>\n<p>Like Musk, Aron too has found a following on Twitter and is known to frequently&nbsp;reach out to the company’s investors&nbsp;through the social media platform.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"AMC":"AMC院线"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1159401236","content_text":"AMC Stock dipped more than 6% in morning trading as AMC CEO Adam Aron sold another $9.65m worth of shares\n\nAMC Entertainment Holdings, Inc CEO Adam Aron sold almost $9.65 million worth of shares in the cinema chain earlier this week, according to filings with the U.S. Securities and Exchange Commission.\nWhat Happened:Aron sold 312,500 shares on Dec. 7 and continues to own 95,997 shares in the company.\nAMC insiders have shed more than $70 million in shares this year as the company’s stocks have surged after finding favor with retail investors particularly those on Reddit forum r/WallStreetBets.\nLast month, Aron sold 625,000 shares of AMC, worth $25 million.\nThe company’s CFO Sean Goodman sold 18,316 shares for nearly $565,000, according to a separate filing.\nWhy It Matters:Apart from Aron’s current holdings, there are 2.9 million shares issuable in the future to him based on performance targets,reported Bloomberg.\nGoodman has reportedly sold all his shares in the company but 600,000 shares, subject to continued service or targets, are not included.\nLast month, Aron had said on Twitter that 62.5% of his annual pay is in AMC stock and he sold as it is prudent from the point of view of “estate planning.”\n\nAcross the S&P500, insiders have sold $63.5 billion in shares through November, as per the Wall Street Journal. On Thursday,Tesla Inc CEO Elon Musk sold $963 million worth of the automaker’s stock to fulfill his tax obligations.\nLike Musk, Aron too has found a following on Twitter and is known to frequently reach out to the company’s investors through the social media platform.","news_type":1},"isVote":1,"tweetType":1,"viewCount":434,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0}],"hots":[{"id":605846773,"gmtCreate":1639148160346,"gmtModify":1639148161911,"author":{"id":"4098850726603110","authorId":"4098850726603110","name":"nick name","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":8,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4098850726603110","authorIdStr":"4098850726603110"},"themes":[],"htmlText":"reason ?","listText":"reason ?","text":"reason ?","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":2,"repostSize":0,"link":"https://laohu8.com/post/605846773","repostId":"1159401236","repostType":2,"repost":{"id":"1159401236","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1639148053,"share":"https://www.laohu8.com/m/news/1159401236?lang=&edition=full","pubTime":"2021-12-10 22:54","market":"us","language":"en","title":"AMC Stock dipped more than 6% in morning trading","url":"https://stock-news.laohu8.com/highlight/detail?id=1159401236","media":"Tiger Newspress","summary":"AMC Stock dipped more than 6% in morning trading as AMC CEO Adam Aron sold another $9.65m worth of s","content":"<p>AMC Stock dipped more than 6% in morning trading&nbsp;as&nbsp;AMC CEO Adam Aron sold another $9.65m worth of shares</p>\n<p><img src=\"https://static.tigerbbs.com/938e1608b0f5bf6a71276c3ce2c87761\" tg-width=\"840\" tg-height=\"470\" referrerpolicy=\"no-referrer\"></p>\n<p><b>AMC Entertainment Holdings, Inc</b>&nbsp;CEO&nbsp;<b>Adam Aron</b>&nbsp;sold almost $9.65 million worth of shares in the cinema chain earlier this week, according to filings with the U.S. Securities and Exchange Commission.</p>\n<p><b>What Happened:</b>Aron sold 312,500 shares on Dec. 7 and continues to own 95,997 shares in the company.</p>\n<p>AMC insiders have shed more than $70 million in shares this year as the company’s stocks have surged after finding favor with retail investors particularly those on Reddit forum r/WallStreetBets.</p>\n<p>Last month, Aron sold 625,000 shares of AMC, worth $25 million.</p>\n<p>The company’s CFO&nbsp;<b>Sean Goodman</b>&nbsp;sold 18,316 shares for nearly $565,000, according to a separate filing.</p>\n<p><b>Why It Matters:</b>Apart from Aron’s current holdings, there are 2.9 million shares issuable in the future to him based on performance targets,reported&nbsp;Bloomberg.</p>\n<p>Goodman has reportedly sold all his shares in the company but 600,000 shares, subject to continued service or targets, are not included.</p>\n<p>Last month, Aron had said on Twitter that 62.5% of his annual pay is in AMC stock and he sold as it is prudent from the point of view of “estate planning.”</p>\n<p><img src=\"https://static.tigerbbs.com/2e3906f6b3a546270106711a8736d511\" tg-width=\"830\" tg-height=\"524\" referrerpolicy=\"no-referrer\" width=\"100%\" height=\"auto\"></p>\n<p>Across the S&amp;P500, insiders have sold $63.5 billion in shares through November, as per the Wall Street Journal. On Thursday,<b>Tesla Inc</b>&nbsp;CEO&nbsp;<b>Elon Musk</b>&nbsp;sold $963 million worth of the automaker’s stock to&nbsp;fulfill his tax obligations.</p>\n<p>Like Musk, Aron too has found a following on Twitter and is known to frequently&nbsp;reach out to the company’s investors&nbsp;through the social media platform.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>AMC Stock dipped more than 6% in morning trading</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nAMC Stock dipped more than 6% in morning trading\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time\">2021-12-10 22:54</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>AMC Stock dipped more than 6% in morning trading&nbsp;as&nbsp;AMC CEO Adam Aron sold another $9.65m worth of shares</p>\n<p><img src=\"https://static.tigerbbs.com/938e1608b0f5bf6a71276c3ce2c87761\" tg-width=\"840\" tg-height=\"470\" referrerpolicy=\"no-referrer\"></p>\n<p><b>AMC Entertainment Holdings, Inc</b>&nbsp;CEO&nbsp;<b>Adam Aron</b>&nbsp;sold almost $9.65 million worth of shares in the cinema chain earlier this week, according to filings with the U.S. Securities and Exchange Commission.</p>\n<p><b>What Happened:</b>Aron sold 312,500 shares on Dec. 7 and continues to own 95,997 shares in the company.</p>\n<p>AMC insiders have shed more than $70 million in shares this year as the company’s stocks have surged after finding favor with retail investors particularly those on Reddit forum r/WallStreetBets.</p>\n<p>Last month, Aron sold 625,000 shares of AMC, worth $25 million.</p>\n<p>The company’s CFO&nbsp;<b>Sean Goodman</b>&nbsp;sold 18,316 shares for nearly $565,000, according to a separate filing.</p>\n<p><b>Why It Matters:</b>Apart from Aron’s current holdings, there are 2.9 million shares issuable in the future to him based on performance targets,reported&nbsp;Bloomberg.</p>\n<p>Goodman has reportedly sold all his shares in the company but 600,000 shares, subject to continued service or targets, are not included.</p>\n<p>Last month, Aron had said on Twitter that 62.5% of his annual pay is in AMC stock and he sold as it is prudent from the point of view of “estate planning.”</p>\n<p><img src=\"https://static.tigerbbs.com/2e3906f6b3a546270106711a8736d511\" tg-width=\"830\" tg-height=\"524\" referrerpolicy=\"no-referrer\" width=\"100%\" height=\"auto\"></p>\n<p>Across the S&amp;P500, insiders have sold $63.5 billion in shares through November, as per the Wall Street Journal. On Thursday,<b>Tesla Inc</b>&nbsp;CEO&nbsp;<b>Elon Musk</b>&nbsp;sold $963 million worth of the automaker’s stock to&nbsp;fulfill his tax obligations.</p>\n<p>Like Musk, Aron too has found a following on Twitter and is known to frequently&nbsp;reach out to the company’s investors&nbsp;through the social media platform.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"AMC":"AMC院线"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1159401236","content_text":"AMC Stock dipped more than 6% in morning trading as AMC CEO Adam Aron sold another $9.65m worth of shares\n\nAMC Entertainment Holdings, Inc CEO Adam Aron sold almost $9.65 million worth of shares in the cinema chain earlier this week, according to filings with the U.S. Securities and Exchange Commission.\nWhat Happened:Aron sold 312,500 shares on Dec. 7 and continues to own 95,997 shares in the company.\nAMC insiders have shed more than $70 million in shares this year as the company’s stocks have surged after finding favor with retail investors particularly those on Reddit forum r/WallStreetBets.\nLast month, Aron sold 625,000 shares of AMC, worth $25 million.\nThe company’s CFO Sean Goodman sold 18,316 shares for nearly $565,000, according to a separate filing.\nWhy It Matters:Apart from Aron’s current holdings, there are 2.9 million shares issuable in the future to him based on performance targets,reported Bloomberg.\nGoodman has reportedly sold all his shares in the company but 600,000 shares, subject to continued service or targets, are not included.\nLast month, Aron had said on Twitter that 62.5% of his annual pay is in AMC stock and he sold as it is prudent from the point of view of “estate planning.”\n\nAcross the S&P500, insiders have sold $63.5 billion in shares through November, as per the Wall Street Journal. On Thursday,Tesla Inc CEO Elon Musk sold $963 million worth of the automaker’s stock to fulfill his tax obligations.\nLike Musk, Aron too has found a following on Twitter and is known to frequently reach out to the company’s investors through the social media platform.","news_type":1},"isVote":1,"tweetType":1,"viewCount":434,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":691210616,"gmtCreate":1640193889962,"gmtModify":1640193889962,"author":{"id":"4098850726603110","authorId":"4098850726603110","name":"nick name","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":8,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4098850726603110","authorIdStr":"4098850726603110"},"themes":[],"htmlText":"overreact..","listText":"overreact..","text":"overreact..","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/691210616","repostId":"1163953446","repostType":2,"repost":{"id":"1163953446","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1640182473,"share":"https://www.laohu8.com/m/news/1163953446?lang=&edition=full","pubTime":"2021-12-22 22:14","market":"us","language":"en","title":"Allakos slumps 87%, draws analysts downgrade on 'disappointing' lirentelimab data","url":"https://stock-news.laohu8.com/highlight/detail?id=1163953446","media":"Tiger Newspress","summary":"Allakos continues to slide, falls 87.4% premarket following yesterday's announcement that its late-s","content":"<p>Allakos&nbsp;continues to slide,&nbsp;falls 87.4% premarket&nbsp;following yesterday's announcement that its late-stage studies, KRYPTOS and ENIGMA 2failed to achieve statistical significance.</p>\n<p><img src=\"https://static.tigerbbs.com/961eae374dfe4dd479394caaf470012c\" tg-width=\"714\" tg-height=\"590\" width=\"100%\" height=\"auto\"></p>\n<p>The studies met their histologic co-primary endpoints but failed to achieve symptomatic endpoints.</p>\n<p>In ENIGMA, patients treated with lirentelimab achieved a 10.0-point reduction in Total Symptom Score-6 (TSS-6) at weeks 23-24 from baseline (baseline = 29.5) compared to an 11.5-point reduction in the placebo group (baseline = 27.7; p=0.343).</p>\n<p>On the second co-primary endpoint of absolute mean change in patient reported Dysphagia Symptom Questionnaire in KRYPTOS trial, the high-dose group achieved a 17.4-point reduction, the low-dose group achieved an 11.9-point reduction and placebo achieved a 14.6-point reduction.</p>\n<p>Following this disappointing result, several analysts lowered their ratings of the stock and slashed the price targets.</p>\n<p>William Blair downgraded the stock to Market Perform from Outperform.</p>\n<p>Analysts of the firm say, \"while we believe lirentelimab has shown clear evidence of histologic activity against eosinophils and mast cells, the failure to achieve co-primary endpoints of patient reported symptoms in both studies raises questions about whether these histologic improvements can translate into clinical improvements.\"</p>\n<p>With lirentelimab performing worse than placebo, there are clearly questions as to why the clean results in Phase II didn’t translate, the analyst notes.</p>\n<p>Cowen analyst Joseph Thome has also cut the recommendation on Allakos to Market Perform from Outperform without the price target (PT) pending pipeline clarity.</p>\n<p>SVB Leerink analyst Thomas Smith downgraded the stock to Market Perform from Outperform, with PT of $17.</p>\n<p>Barclays analyst Carter Gould lowered the firm's PT on Allakos to $8 from $36 and keeps an Underweight rating. The company's lead asset failed in key Phase 3 studies, Gould tells investors in a research note. He views this as the \"end game\" for lirentelimab.</p>\n<p>Morgan Stanley says Allakos' disappointing data increase&nbsp;eosinophilic gastrointestinal diseases (EGIDs) uncertainty.</p>\n<p>Jefferies analyst Maury Raycroft cut the recommendation on&nbsp;Allakos&nbsp;to Hold from Buy.</p>\n<p>LifeSci Capital analyst Samuel Slutsky downgraded the stock to Market Perform from Outperform.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Allakos slumps 87%, draws analysts downgrade on 'disappointing' lirentelimab data</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nAllakos slumps 87%, draws analysts downgrade on 'disappointing' lirentelimab data\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time\">2021-12-22 22:14</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>Allakos&nbsp;continues to slide,&nbsp;falls 87.4% premarket&nbsp;following yesterday's announcement that its late-stage studies, KRYPTOS and ENIGMA 2failed to achieve statistical significance.</p>\n<p><img src=\"https://static.tigerbbs.com/961eae374dfe4dd479394caaf470012c\" tg-width=\"714\" tg-height=\"590\" width=\"100%\" height=\"auto\"></p>\n<p>The studies met their histologic co-primary endpoints but failed to achieve symptomatic endpoints.</p>\n<p>In ENIGMA, patients treated with lirentelimab achieved a 10.0-point reduction in Total Symptom Score-6 (TSS-6) at weeks 23-24 from baseline (baseline = 29.5) compared to an 11.5-point reduction in the placebo group (baseline = 27.7; p=0.343).</p>\n<p>On the second co-primary endpoint of absolute mean change in patient reported Dysphagia Symptom Questionnaire in KRYPTOS trial, the high-dose group achieved a 17.4-point reduction, the low-dose group achieved an 11.9-point reduction and placebo achieved a 14.6-point reduction.</p>\n<p>Following this disappointing result, several analysts lowered their ratings of the stock and slashed the price targets.</p>\n<p>William Blair downgraded the stock to Market Perform from Outperform.</p>\n<p>Analysts of the firm say, \"while we believe lirentelimab has shown clear evidence of histologic activity against eosinophils and mast cells, the failure to achieve co-primary endpoints of patient reported symptoms in both studies raises questions about whether these histologic improvements can translate into clinical improvements.\"</p>\n<p>With lirentelimab performing worse than placebo, there are clearly questions as to why the clean results in Phase II didn’t translate, the analyst notes.</p>\n<p>Cowen analyst Joseph Thome has also cut the recommendation on Allakos to Market Perform from Outperform without the price target (PT) pending pipeline clarity.</p>\n<p>SVB Leerink analyst Thomas Smith downgraded the stock to Market Perform from Outperform, with PT of $17.</p>\n<p>Barclays analyst Carter Gould lowered the firm's PT on Allakos to $8 from $36 and keeps an Underweight rating. The company's lead asset failed in key Phase 3 studies, Gould tells investors in a research note. He views this as the \"end game\" for lirentelimab.</p>\n<p>Morgan Stanley says Allakos' disappointing data increase&nbsp;eosinophilic gastrointestinal diseases (EGIDs) uncertainty.</p>\n<p>Jefferies analyst Maury Raycroft cut the recommendation on&nbsp;Allakos&nbsp;to Hold from Buy.</p>\n<p>LifeSci Capital analyst Samuel Slutsky downgraded the stock to Market Perform from Outperform.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"ALLK":"Allakos Inc."},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1163953446","content_text":"Allakos continues to slide, falls 87.4% premarket following yesterday's announcement that its late-stage studies, KRYPTOS and ENIGMA 2failed to achieve statistical significance.\n\nThe studies met their histologic co-primary endpoints but failed to achieve symptomatic endpoints.\nIn ENIGMA, patients treated with lirentelimab achieved a 10.0-point reduction in Total Symptom Score-6 (TSS-6) at weeks 23-24 from baseline (baseline = 29.5) compared to an 11.5-point reduction in the placebo group (baseline = 27.7; p=0.343).\nOn the second co-primary endpoint of absolute mean change in patient reported Dysphagia Symptom Questionnaire in KRYPTOS trial, the high-dose group achieved a 17.4-point reduction, the low-dose group achieved an 11.9-point reduction and placebo achieved a 14.6-point reduction.\nFollowing this disappointing result, several analysts lowered their ratings of the stock and slashed the price targets.\nWilliam Blair downgraded the stock to Market Perform from Outperform.\nAnalysts of the firm say, \"while we believe lirentelimab has shown clear evidence of histologic activity against eosinophils and mast cells, the failure to achieve co-primary endpoints of patient reported symptoms in both studies raises questions about whether these histologic improvements can translate into clinical improvements.\"\nWith lirentelimab performing worse than placebo, there are clearly questions as to why the clean results in Phase II didn’t translate, the analyst notes.\nCowen analyst Joseph Thome has also cut the recommendation on Allakos to Market Perform from Outperform without the price target (PT) pending pipeline clarity.\nSVB Leerink analyst Thomas Smith downgraded the stock to Market Perform from Outperform, with PT of $17.\nBarclays analyst Carter Gould lowered the firm's PT on Allakos to $8 from $36 and keeps an Underweight rating. The company's lead asset failed in key Phase 3 studies, Gould tells investors in a research note. He views this as the \"end game\" for lirentelimab.\nMorgan Stanley says Allakos' disappointing data increase eosinophilic gastrointestinal diseases (EGIDs) uncertainty.\nJefferies analyst Maury Raycroft cut the recommendation on Allakos to Hold from Buy.\nLifeSci Capital analyst Samuel Slutsky downgraded the stock to Market Perform from Outperform.","news_type":1},"isVote":1,"tweetType":1,"viewCount":747,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":691219244,"gmtCreate":1640194155945,"gmtModify":1640194156071,"author":{"id":"4098850726603110","authorId":"4098850726603110","name":"nick name","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":8,"crmLevelSwitch":0,"followedFlag":false,"idStr":"4098850726603110","authorIdStr":"4098850726603110"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/ALLK\">$Allakos Inc.(ALLK)$</a>is the company still operating ? overreact !","listText":"<a href=\"https://laohu8.com/S/ALLK\">$Allakos Inc.(ALLK)$</a>is the company still operating ? overreact !","text":"$Allakos Inc.(ALLK)$is the company still operating ? overreact !","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/691219244","isVote":1,"tweetType":1,"viewCount":566,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0}],"lives":[]}