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Eagleeye
2021-09-30
Will avoid Nikola ...beware...
4 Stocks Expected to Increase Sales 25,750% to 2,970,000% in 5 Years
Eagleeye
2021-03-25
after Nasdaq
The Hang Seng Index fell 1.04% at the opening. Baidu Group fell more than 9%
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avoid Nikola ...beware...","listText":"Will avoid Nikola ...beware...","text":"Will avoid Nikola ...beware...","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/865481660","repostId":"2171937752","repostType":4,"repost":{"id":"2171937752","kind":"highlight","pubTimestamp":1633002256,"share":"https://www.laohu8.com/m/news/2171937752?lang=&edition=full","pubTime":"2021-09-30 19:44","market":"us","language":"en","title":"4 Stocks Expected to Increase Sales 25,750% to 2,970,000% in 5 Years","url":"https://stock-news.laohu8.com/highlight/detail?id=2171937752","media":"Motley Fool","summary":"These companies could deliver jaw-dropping revenue growth through mid-decade.","content":"<p>High-growth stocks have dominated Wall Street for more than a decade -- and with good reason. Historically low lending rates and an accommodative monetary policy have paved the way for fast-paced companies to borrow at attractive rates.</p>\n<p>But for some companies, sales growth is about to kick into high gear. When you're building a business from the ground up, going from practically nothing in sales to hundreds of millions or billions of dollars in revenue in just a couple of years can be a jaw-dropping experience.</p>\n<p>The following four companies are expected to do just that. According to Wall Street's consensus estimates, these four stocks are forecast to increase sales by 25,750% to as much as 2,970,000% (that's nearly 3 million percent) over the next five years.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/ee55796575e48ba3143c099af095e386\" tg-width=\"700\" tg-height=\"535\" width=\"100%\" height=\"auto\"><span>Image source: Getty Images.</span></p>\n<h2>Vaxart: 25,752% implied sales growth by 2025</h2>\n<p>A clinical-stage biotech stock angling for its first approved therapy is a perfect example of a business that could grow from a relatively small amount of non-recurring revenue to a considerably larger sum of recurring sales. Drug-developer <b>Vaxart</b> (NASDAQ:VXRT) is expected to increase its annual sales from the $4.05 million reported in 2020 to a consensus estimate of $1.047 billion by mid-decade. That's an increase of about 25,750%, if Wall Street's numbers prove accurate.</p>\n<p>Vaxart's future is pinned to the success of its VAAST platform. \"VAAST\" stands for Vector-Adjuvant-Antigen Standardized Technology and encompasses the company's attempts to develop proprietary oral vaccines. Whereas standard vaccines administered in a shot can activate systemic immunity, oral-vaccine tablets would be designed to activate systemic and mucosal immunity in the intestines, lungs, nose, and mouth. In other words, this dual-action approach could carry better immunity against potentially deadly viruses.</p>\n<p>The oral vaccine that's arguably received the most attention for Vaxart is VXA-CoV2-1, an early-stage tablet designed to combat the coronavirus disease 2019 (COVID-19). In May, Vaxart announced that its phase 1 study of VXA-CoV2-1 led to clear immune response in participants, although high levels of neutralizing antibodies weren't present. Traditional shot-in-the-arm vaccines have led to high levels of neutralizing antibodies in clinical trials.</p>\n<p>But Vaxart's work isn't close to being finished. In early August, it received the go-ahead from the U.S. Food and Drug Administration (FDA) to commence an oral-tablet study for a very specific protein to combat COVID-19. It could be some time before investors know if oral vaccines are a viable solution, but the convenience factor certainly makes this trial worth watching.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/650d01a926fded89c361069c76a528f5\" tg-width=\"700\" tg-height=\"466\" width=\"100%\" height=\"auto\"><span>Image source: Getty Images.</span></p>\n<h2>CRISPR Technologies: 191,416% implied sales growth by 2025</h2>\n<p>Did I mention that clinical-stage biotech stocks are a great source of jaw-dropping growth over the next decade? <b>CRISPR Therapeutics</b> (NASDAQ:CRSP), a company leaning on gene-editing technology to precisely alter genomic DNA and tackle hard-to-treat diseases, is expected to see sales climb from $719,000 in 2020 to a consensus of $1.377 billion by 2025. That's an improvement of more than 191,000% in five years.</p>\n<p>Arguably the biggest positive for CRISPR is that it's working with <b>Vertex Pharmaceuticals</b> (NASDAQ:VRTX) in the development of CTX001 for the treatment of transfusion-dependent beta thalassemia (TDT) and sickle cell disease (SCD). Vertex has a storied history of developing novel therapies for hard-to-treat illnesses, such as cystic fibrosis.</p>\n<p>It also doesn't hurt that Vertex's deep pockets are helping to lift CRISPR's bank account. Following a $900 million collaboration payment in the second quarter, CRISPR was sitting on nearly $2.6 billion in cash, cash equivalents, and marketable securities. That's plenty of capital to fund its ongoing clinical studies.</p>\n<p>Initial trial data for CTX001 has also been encouraging. At the European Hematology Association's annual meeting in June, the company announced that all 15 patients with TDT were transfusion-free after follow-ups of at least three months. TDT patients can require weekly transfusions, depending on the severity of their illnesses. Management believes regulatory filings, assuming all goes well in clinical studies, could come by or before mid-2023.</p>\n<p>While CRISPR Technologies is far from the only company looking to tackle TDT and SCD, it's among the best funded and has Vertex in its corner. That gives it a better-than-average chance of success, at least in my book.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/a38605bee8e62f3e8aa414fa24278e7e\" tg-width=\"700\" tg-height=\"466\" width=\"100%\" height=\"auto\"><span>Image source: Getty Images.</span></p>\n<h2>Ocugen: 604,551% implied sales growth by 2025</h2>\n<p>Yet another clinical-stage biotech company expected to see sales go from virtually zero to a big number with a lot of zeroes is <b>Ocugen</b> (NASDAQ:OCGN). After the company reported $43,000 in sales last year, Wall Street's consensus has it generating $260 million in full-year sales by 2025. We're talking about a nearly 605,000% sales increase in five years.</p>\n<p>Not to sound like a broken record, but a COVID-19 vaccine is Ocugen's potential catalyst. The company has partnered with India's Bharat Biotech for the commercialization of Covaxin. A phase 3 trial of 25,800 adults aged 18 and up in India demonstrated a vaccine efficacy of 77.8% for symptomatic infections, 63.6% against asymptomatic infections, and most importantly was 93.4% effective against severe COVID-19 disease. The July-reported data from Bharat also showed a 65.2% efficacy against the delta variant.</p>\n<p>With so many people left to be vaccinated, this probably sounds like a slam-dunk for some form of emergency authorization use in developed or emerging markets. However, there's a big problem for Ocugen: It only has co-commercialization rights for Covaxin in the U.S. and Canada. The U.S. has ordered more-than-enough vaccines to inoculate all eligible Americans, and likely has doses in reserve should booster shots become necessary. The same could be said for Canada, which invested heavily in vaccine purchases.</p>\n<p>While there's no such thing as having too many vaccine options during a pandemic, Covaxin's initial efficacy doesn't pop quite like the vaccines from <b>Moderna</b>, <b>Pfizer</b>/<b>BioNTech</b>, or even <b>Novavax</b>, which looks to be nearing its own emergency use authorization in the United States. Suffice it to say, Ocugen's sales forecast may prove unattainable.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/deae33b8912cffd8d0ba896164abff66\" tg-width=\"700\" tg-height=\"378\" width=\"100%\" height=\"auto\"><span>A rendering of the all-electric Nikola Tre semi. Image source: Nikola.</span></p>\n<h2>Nikola: 2,970,426% implied sales growth by 2025</h2>\n<p>However, the crème de la crème of growth opportunities, at least pertaining to this list, is electric vehicle (EV) manufacturer <b>Nikola</b> (NASDAQ:NKLA). The expectation is that we'll see Nikola's sales catapult from a reported $95,000 in 2020 to a consensus of $2.822 billion by 2025. This equates to almost a 3 million percent jump in annual revenue.</p>\n<p>The growth opportunity for EVs is pretty straightforward. With developed countries like the U.S. tackling climate change head-on, replacing fossil-fuel-burning vehicles with alternative-energy vehicles is <a href=\"https://laohu8.com/S/AONE.U\">one</a> of the easiest ways to make a difference. It's going to take decades for consumers and businesses to make this shift, which leaves plenty of room for multiple EV manufacturers to thrive.</p>\n<p>The issue for Nikola is that it's dealing with a public relations mess. Last year, short-side firm Hindenburg Research released a report that alleged Nikola was a fraud. Even though an independent review found that many of Hindenburg's allegations weren't true, it was discovered that founder Trevor Milton's statements regarding pre-sells weren't accurate.</p>\n<p>Despite stepping down last year, Milton was indicted by the U.S. Department of Justice on three charges of misleading investors. Ultimately, Nikola will have to overcome a breach of trust to sell its vehicles, and it likely will need a lot more cash than it has now to build up its production. Personally, I'm skeptical the company will reach this lofty sales consensus by mid-decade.</p>","source":"fool_stock","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>4 Stocks Expected to Increase Sales 25,750% to 2,970,000% in 5 Years</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n4 Stocks Expected to Increase Sales 25,750% to 2,970,000% in 5 Years\n</h2>\n\n<h4 class=\"meta\">\n\n\n2021-09-30 19:44 GMT+8 <a href=https://www.fool.com/investing/2021/09/30/4-stocks-increase-sales-25750-to-2970000-5-years/><strong>Motley Fool</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>High-growth stocks have dominated Wall Street for more than a decade -- and with good reason. Historically low lending rates and an accommodative monetary policy have paved the way for fast-paced ...</p>\n\n<a href=\"https://www.fool.com/investing/2021/09/30/4-stocks-increase-sales-25750-to-2970000-5-years/\">Web Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"CRSP":"CRISPR Therapeutics AG","OCGN":"Ocugen","VXRT":"Vaxart, Inc","NKLA":"Nikola Corporation"},"source_url":"https://www.fool.com/investing/2021/09/30/4-stocks-increase-sales-25750-to-2970000-5-years/","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2171937752","content_text":"High-growth stocks have dominated Wall Street for more than a decade -- and with good reason. Historically low lending rates and an accommodative monetary policy have paved the way for fast-paced companies to borrow at attractive rates.\nBut for some companies, sales growth is about to kick into high gear. When you're building a business from the ground up, going from practically nothing in sales to hundreds of millions or billions of dollars in revenue in just a couple of years can be a jaw-dropping experience.\nThe following four companies are expected to do just that. According to Wall Street's consensus estimates, these four stocks are forecast to increase sales by 25,750% to as much as 2,970,000% (that's nearly 3 million percent) over the next five years.\nImage source: Getty Images.\nVaxart: 25,752% implied sales growth by 2025\nA clinical-stage biotech stock angling for its first approved therapy is a perfect example of a business that could grow from a relatively small amount of non-recurring revenue to a considerably larger sum of recurring sales. Drug-developer Vaxart (NASDAQ:VXRT) is expected to increase its annual sales from the $4.05 million reported in 2020 to a consensus estimate of $1.047 billion by mid-decade. That's an increase of about 25,750%, if Wall Street's numbers prove accurate.\nVaxart's future is pinned to the success of its VAAST platform. \"VAAST\" stands for Vector-Adjuvant-Antigen Standardized Technology and encompasses the company's attempts to develop proprietary oral vaccines. Whereas standard vaccines administered in a shot can activate systemic immunity, oral-vaccine tablets would be designed to activate systemic and mucosal immunity in the intestines, lungs, nose, and mouth. In other words, this dual-action approach could carry better immunity against potentially deadly viruses.\nThe oral vaccine that's arguably received the most attention for Vaxart is VXA-CoV2-1, an early-stage tablet designed to combat the coronavirus disease 2019 (COVID-19). In May, Vaxart announced that its phase 1 study of VXA-CoV2-1 led to clear immune response in participants, although high levels of neutralizing antibodies weren't present. Traditional shot-in-the-arm vaccines have led to high levels of neutralizing antibodies in clinical trials.\nBut Vaxart's work isn't close to being finished. In early August, it received the go-ahead from the U.S. Food and Drug Administration (FDA) to commence an oral-tablet study for a very specific protein to combat COVID-19. It could be some time before investors know if oral vaccines are a viable solution, but the convenience factor certainly makes this trial worth watching.\nImage source: Getty Images.\nCRISPR Technologies: 191,416% implied sales growth by 2025\nDid I mention that clinical-stage biotech stocks are a great source of jaw-dropping growth over the next decade? CRISPR Therapeutics (NASDAQ:CRSP), a company leaning on gene-editing technology to precisely alter genomic DNA and tackle hard-to-treat diseases, is expected to see sales climb from $719,000 in 2020 to a consensus of $1.377 billion by 2025. That's an improvement of more than 191,000% in five years.\nArguably the biggest positive for CRISPR is that it's working with Vertex Pharmaceuticals (NASDAQ:VRTX) in the development of CTX001 for the treatment of transfusion-dependent beta thalassemia (TDT) and sickle cell disease (SCD). Vertex has a storied history of developing novel therapies for hard-to-treat illnesses, such as cystic fibrosis.\nIt also doesn't hurt that Vertex's deep pockets are helping to lift CRISPR's bank account. Following a $900 million collaboration payment in the second quarter, CRISPR was sitting on nearly $2.6 billion in cash, cash equivalents, and marketable securities. That's plenty of capital to fund its ongoing clinical studies.\nInitial trial data for CTX001 has also been encouraging. At the European Hematology Association's annual meeting in June, the company announced that all 15 patients with TDT were transfusion-free after follow-ups of at least three months. TDT patients can require weekly transfusions, depending on the severity of their illnesses. Management believes regulatory filings, assuming all goes well in clinical studies, could come by or before mid-2023.\nWhile CRISPR Technologies is far from the only company looking to tackle TDT and SCD, it's among the best funded and has Vertex in its corner. That gives it a better-than-average chance of success, at least in my book.\nImage source: Getty Images.\nOcugen: 604,551% implied sales growth by 2025\nYet another clinical-stage biotech company expected to see sales go from virtually zero to a big number with a lot of zeroes is Ocugen (NASDAQ:OCGN). After the company reported $43,000 in sales last year, Wall Street's consensus has it generating $260 million in full-year sales by 2025. We're talking about a nearly 605,000% sales increase in five years.\nNot to sound like a broken record, but a COVID-19 vaccine is Ocugen's potential catalyst. The company has partnered with India's Bharat Biotech for the commercialization of Covaxin. A phase 3 trial of 25,800 adults aged 18 and up in India demonstrated a vaccine efficacy of 77.8% for symptomatic infections, 63.6% against asymptomatic infections, and most importantly was 93.4% effective against severe COVID-19 disease. The July-reported data from Bharat also showed a 65.2% efficacy against the delta variant.\nWith so many people left to be vaccinated, this probably sounds like a slam-dunk for some form of emergency authorization use in developed or emerging markets. However, there's a big problem for Ocugen: It only has co-commercialization rights for Covaxin in the U.S. and Canada. The U.S. has ordered more-than-enough vaccines to inoculate all eligible Americans, and likely has doses in reserve should booster shots become necessary. The same could be said for Canada, which invested heavily in vaccine purchases.\nWhile there's no such thing as having too many vaccine options during a pandemic, Covaxin's initial efficacy doesn't pop quite like the vaccines from Moderna, Pfizer/BioNTech, or even Novavax, which looks to be nearing its own emergency use authorization in the United States. Suffice it to say, Ocugen's sales forecast may prove unattainable.\nA rendering of the all-electric Nikola Tre semi. Image source: Nikola.\nNikola: 2,970,426% implied sales growth by 2025\nHowever, the crème de la crème of growth opportunities, at least pertaining to this list, is electric vehicle (EV) manufacturer Nikola (NASDAQ:NKLA). The expectation is that we'll see Nikola's sales catapult from a reported $95,000 in 2020 to a consensus of $2.822 billion by 2025. This equates to almost a 3 million percent jump in annual revenue.\nThe growth opportunity for EVs is pretty straightforward. With developed countries like the U.S. tackling climate change head-on, replacing fossil-fuel-burning vehicles with alternative-energy vehicles is one of the easiest ways to make a difference. It's going to take decades for consumers and businesses to make this shift, which leaves plenty of room for multiple EV manufacturers to thrive.\nThe issue for Nikola is that it's dealing with a public relations mess. Last year, short-side firm Hindenburg Research released a report that alleged Nikola was a fraud. Even though an independent review found that many of Hindenburg's allegations weren't true, it was discovered that founder Trevor Milton's statements regarding pre-sells weren't accurate.\nDespite stepping down last year, Milton was indicted by the U.S. Department of Justice on three charges of misleading investors. Ultimately, Nikola will have to overcome a breach of trust to sell its vehicles, and it likely will need a lot more cash than it has now to build up its production. Personally, I'm skeptical the company will reach this lofty sales consensus by mid-decade.","news_type":1},"isVote":1,"tweetType":1,"viewCount":557,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":351749501,"gmtCreate":1616635996403,"gmtModify":1634524809100,"author":{"id":"3574327538823156","authorId":"3574327538823156","name":"Eagleeye","avatar":"https://static.tigerbbs.com/fc4105336c55c92b7ad1a5a05b6bd9ee","crmLevel":2,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3574327538823156","authorIdStr":"3574327538823156"},"themes":[],"htmlText":"after Nasdaq ","listText":"after Nasdaq ","text":"after Nasdaq","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":7,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/351749501","repostId":"1193689570","repostType":4,"repost":{"id":"1193689570","kind":"news","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1616635457,"share":"https://www.laohu8.com/m/news/1193689570?lang=&edition=full","pubTime":"2021-03-25 09:24","market":"hk","language":"en","title":"The Hang Seng Index fell 1.04% at the opening. Baidu Group fell more than 9%","url":"https://stock-news.laohu8.com/highlight/detail?id=1193689570","media":"Tiger Newspress","summary":"Hong Kong stocks opened, and the HSI opened 1.04% lower. Technology stocks and Hong Kong local stock","content":"<p>Hong Kong stocks opened, and the HSI opened 1.04% lower. Technology stocks and Hong Kong local stocks continued to fall under pressure. Tencent Holdings opened nearly 4% lower, hitting the 600 Hong Kong dollar mark.</p><p><img src=\"https://static.tigerbbs.com/fabd51f049677ea8ecfac90f9b86bb5f\" tg-width=\"840\" tg-height=\"470\" referrerpolicy=\"no-referrer\"></p><p>Baidu opened 9.09% lower and reported 228 Hong Kong dollars, a record low. The turnover temporarily recorded 77.8 million Hong Kong dollars.</p><p><img src=\"https://static.tigerbbs.com/f36b74df301e2a4ac23e0f02f3c971c2\" tg-width=\"840\" tg-height=\"470\"></p><p>Xiaomi Group fell 4.6%, and its revenue and net profit performance in 2020 fell short of market expectations.</p><p>JD.com and Meituan both fell more than 3%.</p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>The Hang Seng Index fell 1.04% at the opening. Baidu Group fell more than 9%</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nThe Hang Seng Index fell 1.04% at the opening. Baidu Group fell more than 9%\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">Tiger Newspress </p>\n<p class=\"h-time\">2021-03-25 09:24</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p>Hong Kong stocks opened, and the HSI opened 1.04% lower. Technology stocks and Hong Kong local stocks continued to fall under pressure. Tencent Holdings opened nearly 4% lower, hitting the 600 Hong Kong dollar mark.</p><p><img src=\"https://static.tigerbbs.com/fabd51f049677ea8ecfac90f9b86bb5f\" tg-width=\"840\" tg-height=\"470\" referrerpolicy=\"no-referrer\"></p><p>Baidu opened 9.09% lower and reported 228 Hong Kong dollars, a record low. The turnover temporarily recorded 77.8 million Hong Kong dollars.</p><p><img src=\"https://static.tigerbbs.com/f36b74df301e2a4ac23e0f02f3c971c2\" tg-width=\"840\" tg-height=\"470\"></p><p>Xiaomi Group fell 4.6%, and its revenue and net profit performance in 2020 fell short of market expectations.</p><p>JD.com and Meituan both fell more than 3%.</p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/c1cb237e736a4e03c939622e7b71e8e7","relate_stocks":{"00700":"腾讯控股"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1193689570","content_text":"Hong Kong stocks opened, and the HSI opened 1.04% lower. Technology stocks and Hong Kong local stocks continued to fall under pressure. Tencent Holdings opened nearly 4% lower, hitting the 600 Hong Kong dollar mark.Baidu opened 9.09% lower and reported 228 Hong Kong dollars, a record low. The turnover temporarily recorded 77.8 million Hong Kong dollars.Xiaomi Group fell 4.6%, and its revenue and net profit performance in 2020 fell short of market expectations.JD.com and Meituan both fell more than 3%.","news_type":1},"isVote":1,"tweetType":1,"viewCount":539,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0}],"hots":[{"id":351749501,"gmtCreate":1616635996403,"gmtModify":1634524809100,"author":{"id":"3574327538823156","authorId":"3574327538823156","name":"Eagleeye","avatar":"https://static.tigerbbs.com/fc4105336c55c92b7ad1a5a05b6bd9ee","crmLevel":2,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3574327538823156","idStr":"3574327538823156"},"themes":[],"htmlText":"after Nasdaq ","listText":"after Nasdaq ","text":"after Nasdaq","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":7,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/351749501","repostId":"1193689570","repostType":4,"isVote":1,"tweetType":1,"viewCount":539,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"EN","totalScore":0},{"id":865481660,"gmtCreate":1633010927217,"gmtModify":1633010927333,"author":{"id":"3574327538823156","authorId":"3574327538823156","name":"Eagleeye","avatar":"https://static.tigerbbs.com/fc4105336c55c92b7ad1a5a05b6bd9ee","crmLevel":2,"crmLevelSwitch":0,"followedFlag":false,"authorIdStr":"3574327538823156","idStr":"3574327538823156"},"themes":[],"htmlText":"Will avoid Nikola ...beware...","listText":"Will avoid Nikola ...beware...","text":"Will avoid Nikola ...beware...","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/865481660","repostId":"2171937752","repostType":4,"repost":{"id":"2171937752","kind":"highlight","pubTimestamp":1633002256,"share":"https://www.laohu8.com/m/news/2171937752?lang=&edition=full","pubTime":"2021-09-30 19:44","market":"us","language":"en","title":"4 Stocks Expected to Increase Sales 25,750% to 2,970,000% in 5 Years","url":"https://stock-news.laohu8.com/highlight/detail?id=2171937752","media":"Motley Fool","summary":"These companies could deliver jaw-dropping revenue growth through mid-decade.","content":"<p>High-growth stocks have dominated Wall Street for more than a decade -- and with good reason. Historically low lending rates and an accommodative monetary policy have paved the way for fast-paced companies to borrow at attractive rates.</p>\n<p>But for some companies, sales growth is about to kick into high gear. When you're building a business from the ground up, going from practically nothing in sales to hundreds of millions or billions of dollars in revenue in just a couple of years can be a jaw-dropping experience.</p>\n<p>The following four companies are expected to do just that. According to Wall Street's consensus estimates, these four stocks are forecast to increase sales by 25,750% to as much as 2,970,000% (that's nearly 3 million percent) over the next five years.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/ee55796575e48ba3143c099af095e386\" tg-width=\"700\" tg-height=\"535\" width=\"100%\" height=\"auto\"><span>Image source: Getty Images.</span></p>\n<h2>Vaxart: 25,752% implied sales growth by 2025</h2>\n<p>A clinical-stage biotech stock angling for its first approved therapy is a perfect example of a business that could grow from a relatively small amount of non-recurring revenue to a considerably larger sum of recurring sales. Drug-developer <b>Vaxart</b> (NASDAQ:VXRT) is expected to increase its annual sales from the $4.05 million reported in 2020 to a consensus estimate of $1.047 billion by mid-decade. That's an increase of about 25,750%, if Wall Street's numbers prove accurate.</p>\n<p>Vaxart's future is pinned to the success of its VAAST platform. \"VAAST\" stands for Vector-Adjuvant-Antigen Standardized Technology and encompasses the company's attempts to develop proprietary oral vaccines. Whereas standard vaccines administered in a shot can activate systemic immunity, oral-vaccine tablets would be designed to activate systemic and mucosal immunity in the intestines, lungs, nose, and mouth. In other words, this dual-action approach could carry better immunity against potentially deadly viruses.</p>\n<p>The oral vaccine that's arguably received the most attention for Vaxart is VXA-CoV2-1, an early-stage tablet designed to combat the coronavirus disease 2019 (COVID-19). In May, Vaxart announced that its phase 1 study of VXA-CoV2-1 led to clear immune response in participants, although high levels of neutralizing antibodies weren't present. Traditional shot-in-the-arm vaccines have led to high levels of neutralizing antibodies in clinical trials.</p>\n<p>But Vaxart's work isn't close to being finished. In early August, it received the go-ahead from the U.S. Food and Drug Administration (FDA) to commence an oral-tablet study for a very specific protein to combat COVID-19. It could be some time before investors know if oral vaccines are a viable solution, but the convenience factor certainly makes this trial worth watching.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/650d01a926fded89c361069c76a528f5\" tg-width=\"700\" tg-height=\"466\" width=\"100%\" height=\"auto\"><span>Image source: Getty Images.</span></p>\n<h2>CRISPR Technologies: 191,416% implied sales growth by 2025</h2>\n<p>Did I mention that clinical-stage biotech stocks are a great source of jaw-dropping growth over the next decade? <b>CRISPR Therapeutics</b> (NASDAQ:CRSP), a company leaning on gene-editing technology to precisely alter genomic DNA and tackle hard-to-treat diseases, is expected to see sales climb from $719,000 in 2020 to a consensus of $1.377 billion by 2025. That's an improvement of more than 191,000% in five years.</p>\n<p>Arguably the biggest positive for CRISPR is that it's working with <b>Vertex Pharmaceuticals</b> (NASDAQ:VRTX) in the development of CTX001 for the treatment of transfusion-dependent beta thalassemia (TDT) and sickle cell disease (SCD). Vertex has a storied history of developing novel therapies for hard-to-treat illnesses, such as cystic fibrosis.</p>\n<p>It also doesn't hurt that Vertex's deep pockets are helping to lift CRISPR's bank account. Following a $900 million collaboration payment in the second quarter, CRISPR was sitting on nearly $2.6 billion in cash, cash equivalents, and marketable securities. That's plenty of capital to fund its ongoing clinical studies.</p>\n<p>Initial trial data for CTX001 has also been encouraging. At the European Hematology Association's annual meeting in June, the company announced that all 15 patients with TDT were transfusion-free after follow-ups of at least three months. TDT patients can require weekly transfusions, depending on the severity of their illnesses. Management believes regulatory filings, assuming all goes well in clinical studies, could come by or before mid-2023.</p>\n<p>While CRISPR Technologies is far from the only company looking to tackle TDT and SCD, it's among the best funded and has Vertex in its corner. That gives it a better-than-average chance of success, at least in my book.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/a38605bee8e62f3e8aa414fa24278e7e\" tg-width=\"700\" tg-height=\"466\" width=\"100%\" height=\"auto\"><span>Image source: Getty Images.</span></p>\n<h2>Ocugen: 604,551% implied sales growth by 2025</h2>\n<p>Yet another clinical-stage biotech company expected to see sales go from virtually zero to a big number with a lot of zeroes is <b>Ocugen</b> (NASDAQ:OCGN). After the company reported $43,000 in sales last year, Wall Street's consensus has it generating $260 million in full-year sales by 2025. We're talking about a nearly 605,000% sales increase in five years.</p>\n<p>Not to sound like a broken record, but a COVID-19 vaccine is Ocugen's potential catalyst. The company has partnered with India's Bharat Biotech for the commercialization of Covaxin. A phase 3 trial of 25,800 adults aged 18 and up in India demonstrated a vaccine efficacy of 77.8% for symptomatic infections, 63.6% against asymptomatic infections, and most importantly was 93.4% effective against severe COVID-19 disease. The July-reported data from Bharat also showed a 65.2% efficacy against the delta variant.</p>\n<p>With so many people left to be vaccinated, this probably sounds like a slam-dunk for some form of emergency authorization use in developed or emerging markets. However, there's a big problem for Ocugen: It only has co-commercialization rights for Covaxin in the U.S. and Canada. The U.S. has ordered more-than-enough vaccines to inoculate all eligible Americans, and likely has doses in reserve should booster shots become necessary. The same could be said for Canada, which invested heavily in vaccine purchases.</p>\n<p>While there's no such thing as having too many vaccine options during a pandemic, Covaxin's initial efficacy doesn't pop quite like the vaccines from <b>Moderna</b>, <b>Pfizer</b>/<b>BioNTech</b>, or even <b>Novavax</b>, which looks to be nearing its own emergency use authorization in the United States. Suffice it to say, Ocugen's sales forecast may prove unattainable.</p>\n<p class=\"t-img-caption\"><img src=\"https://static.tigerbbs.com/deae33b8912cffd8d0ba896164abff66\" tg-width=\"700\" tg-height=\"378\" width=\"100%\" height=\"auto\"><span>A rendering of the all-electric Nikola Tre semi. Image source: Nikola.</span></p>\n<h2>Nikola: 2,970,426% implied sales growth by 2025</h2>\n<p>However, the crème de la crème of growth opportunities, at least pertaining to this list, is electric vehicle (EV) manufacturer <b>Nikola</b> (NASDAQ:NKLA). The expectation is that we'll see Nikola's sales catapult from a reported $95,000 in 2020 to a consensus of $2.822 billion by 2025. This equates to almost a 3 million percent jump in annual revenue.</p>\n<p>The growth opportunity for EVs is pretty straightforward. With developed countries like the U.S. tackling climate change head-on, replacing fossil-fuel-burning vehicles with alternative-energy vehicles is <a href=\"https://laohu8.com/S/AONE.U\">one</a> of the easiest ways to make a difference. It's going to take decades for consumers and businesses to make this shift, which leaves plenty of room for multiple EV manufacturers to thrive.</p>\n<p>The issue for Nikola is that it's dealing with a public relations mess. Last year, short-side firm Hindenburg Research released a report that alleged Nikola was a fraud. Even though an independent review found that many of Hindenburg's allegations weren't true, it was discovered that founder Trevor Milton's statements regarding pre-sells weren't accurate.</p>\n<p>Despite stepping down last year, Milton was indicted by the U.S. Department of Justice on three charges of misleading investors. Ultimately, Nikola will have to overcome a breach of trust to sell its vehicles, and it likely will need a lot more cash than it has now to build up its production. Personally, I'm skeptical the company will reach this lofty sales consensus by mid-decade.</p>","source":"fool_stock","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>4 Stocks Expected to Increase Sales 25,750% to 2,970,000% in 5 Years</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\n4 Stocks Expected to Increase Sales 25,750% to 2,970,000% in 5 Years\n</h2>\n\n<h4 class=\"meta\">\n\n\n2021-09-30 19:44 GMT+8 <a href=https://www.fool.com/investing/2021/09/30/4-stocks-increase-sales-25750-to-2970000-5-years/><strong>Motley Fool</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>High-growth stocks have dominated Wall Street for more than a decade -- and with good reason. Historically low lending rates and an accommodative monetary policy have paved the way for fast-paced ...</p>\n\n<a href=\"https://www.fool.com/investing/2021/09/30/4-stocks-increase-sales-25750-to-2970000-5-years/\">Web Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"CRSP":"CRISPR Therapeutics AG","OCGN":"Ocugen","VXRT":"Vaxart, Inc","NKLA":"Nikola Corporation"},"source_url":"https://www.fool.com/investing/2021/09/30/4-stocks-increase-sales-25750-to-2970000-5-years/","is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"2171937752","content_text":"High-growth stocks have dominated Wall Street for more than a decade -- and with good reason. Historically low lending rates and an accommodative monetary policy have paved the way for fast-paced companies to borrow at attractive rates.\nBut for some companies, sales growth is about to kick into high gear. When you're building a business from the ground up, going from practically nothing in sales to hundreds of millions or billions of dollars in revenue in just a couple of years can be a jaw-dropping experience.\nThe following four companies are expected to do just that. According to Wall Street's consensus estimates, these four stocks are forecast to increase sales by 25,750% to as much as 2,970,000% (that's nearly 3 million percent) over the next five years.\nImage source: Getty Images.\nVaxart: 25,752% implied sales growth by 2025\nA clinical-stage biotech stock angling for its first approved therapy is a perfect example of a business that could grow from a relatively small amount of non-recurring revenue to a considerably larger sum of recurring sales. Drug-developer Vaxart (NASDAQ:VXRT) is expected to increase its annual sales from the $4.05 million reported in 2020 to a consensus estimate of $1.047 billion by mid-decade. That's an increase of about 25,750%, if Wall Street's numbers prove accurate.\nVaxart's future is pinned to the success of its VAAST platform. \"VAAST\" stands for Vector-Adjuvant-Antigen Standardized Technology and encompasses the company's attempts to develop proprietary oral vaccines. Whereas standard vaccines administered in a shot can activate systemic immunity, oral-vaccine tablets would be designed to activate systemic and mucosal immunity in the intestines, lungs, nose, and mouth. In other words, this dual-action approach could carry better immunity against potentially deadly viruses.\nThe oral vaccine that's arguably received the most attention for Vaxart is VXA-CoV2-1, an early-stage tablet designed to combat the coronavirus disease 2019 (COVID-19). In May, Vaxart announced that its phase 1 study of VXA-CoV2-1 led to clear immune response in participants, although high levels of neutralizing antibodies weren't present. Traditional shot-in-the-arm vaccines have led to high levels of neutralizing antibodies in clinical trials.\nBut Vaxart's work isn't close to being finished. In early August, it received the go-ahead from the U.S. Food and Drug Administration (FDA) to commence an oral-tablet study for a very specific protein to combat COVID-19. It could be some time before investors know if oral vaccines are a viable solution, but the convenience factor certainly makes this trial worth watching.\nImage source: Getty Images.\nCRISPR Technologies: 191,416% implied sales growth by 2025\nDid I mention that clinical-stage biotech stocks are a great source of jaw-dropping growth over the next decade? CRISPR Therapeutics (NASDAQ:CRSP), a company leaning on gene-editing technology to precisely alter genomic DNA and tackle hard-to-treat diseases, is expected to see sales climb from $719,000 in 2020 to a consensus of $1.377 billion by 2025. That's an improvement of more than 191,000% in five years.\nArguably the biggest positive for CRISPR is that it's working with Vertex Pharmaceuticals (NASDAQ:VRTX) in the development of CTX001 for the treatment of transfusion-dependent beta thalassemia (TDT) and sickle cell disease (SCD). Vertex has a storied history of developing novel therapies for hard-to-treat illnesses, such as cystic fibrosis.\nIt also doesn't hurt that Vertex's deep pockets are helping to lift CRISPR's bank account. Following a $900 million collaboration payment in the second quarter, CRISPR was sitting on nearly $2.6 billion in cash, cash equivalents, and marketable securities. That's plenty of capital to fund its ongoing clinical studies.\nInitial trial data for CTX001 has also been encouraging. At the European Hematology Association's annual meeting in June, the company announced that all 15 patients with TDT were transfusion-free after follow-ups of at least three months. TDT patients can require weekly transfusions, depending on the severity of their illnesses. Management believes regulatory filings, assuming all goes well in clinical studies, could come by or before mid-2023.\nWhile CRISPR Technologies is far from the only company looking to tackle TDT and SCD, it's among the best funded and has Vertex in its corner. That gives it a better-than-average chance of success, at least in my book.\nImage source: Getty Images.\nOcugen: 604,551% implied sales growth by 2025\nYet another clinical-stage biotech company expected to see sales go from virtually zero to a big number with a lot of zeroes is Ocugen (NASDAQ:OCGN). After the company reported $43,000 in sales last year, Wall Street's consensus has it generating $260 million in full-year sales by 2025. We're talking about a nearly 605,000% sales increase in five years.\nNot to sound like a broken record, but a COVID-19 vaccine is Ocugen's potential catalyst. The company has partnered with India's Bharat Biotech for the commercialization of Covaxin. A phase 3 trial of 25,800 adults aged 18 and up in India demonstrated a vaccine efficacy of 77.8% for symptomatic infections, 63.6% against asymptomatic infections, and most importantly was 93.4% effective against severe COVID-19 disease. The July-reported data from Bharat also showed a 65.2% efficacy against the delta variant.\nWith so many people left to be vaccinated, this probably sounds like a slam-dunk for some form of emergency authorization use in developed or emerging markets. However, there's a big problem for Ocugen: It only has co-commercialization rights for Covaxin in the U.S. and Canada. The U.S. has ordered more-than-enough vaccines to inoculate all eligible Americans, and likely has doses in reserve should booster shots become necessary. The same could be said for Canada, which invested heavily in vaccine purchases.\nWhile there's no such thing as having too many vaccine options during a pandemic, Covaxin's initial efficacy doesn't pop quite like the vaccines from Moderna, Pfizer/BioNTech, or even Novavax, which looks to be nearing its own emergency use authorization in the United States. Suffice it to say, Ocugen's sales forecast may prove unattainable.\nA rendering of the all-electric Nikola Tre semi. Image source: Nikola.\nNikola: 2,970,426% implied sales growth by 2025\nHowever, the crème de la crème of growth opportunities, at least pertaining to this list, is electric vehicle (EV) manufacturer Nikola (NASDAQ:NKLA). The expectation is that we'll see Nikola's sales catapult from a reported $95,000 in 2020 to a consensus of $2.822 billion by 2025. This equates to almost a 3 million percent jump in annual revenue.\nThe growth opportunity for EVs is pretty straightforward. With developed countries like the U.S. tackling climate change head-on, replacing fossil-fuel-burning vehicles with alternative-energy vehicles is one of the easiest ways to make a difference. It's going to take decades for consumers and businesses to make this shift, which leaves plenty of room for multiple EV manufacturers to thrive.\nThe issue for Nikola is that it's dealing with a public relations mess. Last year, short-side firm Hindenburg Research released a report that alleged Nikola was a fraud. Even though an independent review found that many of Hindenburg's allegations weren't true, it was discovered that founder Trevor Milton's statements regarding pre-sells weren't accurate.\nDespite stepping down last year, Milton was indicted by the U.S. Department of Justice on three charges of misleading investors. Ultimately, Nikola will have to overcome a breach of trust to sell its vehicles, and it likely will need a lot more cash than it has now to build up its production. Personally, I'm skeptical the company will reach this lofty sales consensus by mid-decade.","news_type":1},"isVote":1,"tweetType":1,"viewCount":557,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0}],"lives":[]}