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2021-06-18

$Sorrento Therapeutics Inc.(SRNE)$怎么看

2021-03-09

$游戏驿站(GME)$挣💰去买SRNE

2021-02-25

$游戏驿站(GME)$这谁能想到呢

2021-02-25

Hihi

2021-02-09

$Sorrento Therapeutics Inc.(SRNE)$现在上车还有机会

2021-01-28

$Sorrento Therapeutics Inc.(SRNE)$目标越来越近

2021-01-27

$Sorrento Therapeutics Inc.(SRNE)$必须见$35

2020-11-12

这篇文章不错，转发给大家看

Sorrento Announces FDA IND Filing Today for COVI-AMG Neutralizing and High Potency Antibody Against SARS-CoV-2

2020-10-29

有够胆的就是接飞刀最好的时间了。

2020-09-30

$Sorrento Therapeutics Inc.(SRNE)$这次上升的更稳

2020-09-23

$Sorrento Therapeutics Inc.(SRNE)$看最后一个多小时的增量，你就应该知道上车或下车。

2020-08-11

$Sorrento Therapeutics Inc.(SRNE)$终于站上18元

2020-08-10

$Sorrento Therapeutics Inc.(SRNE)$我也成绩不错

2020-06-15

期待行情大反弹。

2020-06-14

燃石医学开涨43.64%，后面的行情会怎么走呢？

2020-06-13

惊心动魄的一周在最后半小时给了往后行情一根定海神针。

2020-06-12

这篇文章不错，转发给大家看

@edward28:很多投资者近两天没有把握好盈利，将挣到手的钱又全部做善事了。

2020-06-12

心态不好真的别进股市，这过山车的波动一段人怎可承受呀。

2020-06-11

油股调整到位

2020-06-10

油股调整到位了吧

去老虎APP查看更多动态

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href=\"https://laohu8.com/S/GME\">$游戏驿站(GME)$</a>挣💰去买SRNE","listText":"<a href=\"https://laohu8.com/S/GME\">$游戏驿站(GME)$</a>挣💰去买SRNE","text":"$游戏驿站(GME)$挣💰去买SRNE","images":[{"img":"https://static.tigerbbs.com/d7c4a38fe80797b37bb4e9d2eb18a442","width":"1080","height":"1920"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/329638955","isVote":1,"tweetType":1,"viewCount":1914,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":361313692,"gmtCreate":1614204167416,"gmtModify":1614204167416,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/GME\">$游戏驿站(GME)$</a>这谁能想到呢","listText":"<a href=\"https://laohu8.com/S/GME\">$游戏驿站(GME)$</a>这谁能想到呢","text":"$游戏驿站(GME)$这谁能想到呢","images":[{"img":"https://static.tigerbbs.com/5fcf40c3de359990987a137571c6469f","width":"1080","height":"1920"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":5,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/361313692","isVote":1,"tweetType":1,"viewCount":1689,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":361334736,"gmtCreate":1614203668525,"gmtModify":1614203668525,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"&nbsp;Hihi","listText":"&nbsp;Hihi","text":"Hihi","images":[{"img":"https://static.tigerbbs.com/8f6dbefd16b3d6760a225e0b498b8b5a","width":"1080","height":"1956"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/361334736","isVote":1,"tweetType":1,"viewCount":553,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"EN","totalScore":0},{"id":383913118,"gmtCreate":1612828753134,"gmtModify":1703765524356,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>现在上车还有机会","listText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>现在上车还有机会","text":"$Sorrento Therapeutics Inc.(SRNE)$现在上车还有机会","images":[{"img":"https://static.tigerbbs.com/e5fd2ba5ef4302e557ef6f55cca3798d","width":"1080","height":"1920"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/383913118","isVote":1,"tweetType":1,"viewCount":2473,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":311880162,"gmtCreate":1611774079656,"gmtModify":1703753742849,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>目标越来越近","listText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>目标越来越近","text":"$Sorrento Therapeutics Inc.(SRNE)$目标越来越近","images":[{"img":"https://static.tigerbbs.com/f4a43d04472d23638348204055645be2","width":"1080","height":"1920"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":2,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/311880162","isVote":1,"tweetType":1,"viewCount":2372,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":313209913,"gmtCreate":1611716090432,"gmtModify":1703752582217,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>必须见$35","listText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>必须见$35","text":"$Sorrento Therapeutics Inc.(SRNE)$必须见$35","images":[{"img":"https://static.tigerbbs.com/6d826681b38c8ab6c93ba126180e62d0","width":"1080","height":"1920"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":7,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/313209913","isVote":1,"tweetType":1,"viewCount":1410,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":304942649,"gmtCreate":1605126236481,"gmtModify":1703836347233,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"这篇文章不错，转发给大家看","listText":"这篇文章不错，转发给大家看","text":"这篇文章不错，转发给大家看","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/304942649","repostId":"2082718698","repostType":2,"repost":{"id":"2082718698","pubTimestamp":1604930400,"share":"https://www.laohu8.com/m/news/2082718698?lang=&edition=full","pubTime":"2020-11-09 22:00","market":"us","language":"en","title":"Sorrento Announces FDA IND Filing Today for COVI-AMG Neutralizing and High Potency Antibody Against SARS-CoV-2","url":"https://stock-news.laohu8.com/highlight/detail?id=2082718698","media":"GlobeNewswire","summary":"IND filing today for STI-2020 (COVI-AMG™) for the treatment of COVID-19 in patients with mild sympto","content":"<html><body><ul type=\"disc\">\n<li>IND filing today for STI-2020 (COVI-AMG™) for the treatment of COVID-19 in patients with mild symptoms and a separate safety and pharmacokinetic study in healthy volunteers.</li>\n<li>These initial trials are expected to be followed by pivotal trials with a goal of potentially receiving an EUA (Emergency Use Authorization).</li>\n<li>Animal model data (golden Syrian hamsters infected with SARS-CoV-2) demonstrated a highly effective neutralizing profile.</li>\n<li>This antibody has been engineered for ultra-high potency, with an expected effective dose in humans to be much lower than current known antibodies being assessed by others in active trials, which would allow for a simple IV-push administration that is suitable in the outpatient setting.</li>\n<li>This antibody has been engineered and validated in preclinical studies to avoid antibody-dependent enhancement (ADE) to potentially increase the safety profile.</li>\n<li>Additional <em>in</em> <em>vitro </em>experiments demonstrated the complete virus neutralizing property of STI-2020 against the highly contagious D614G SARS-CoV-2 variant.</li>\n<li>Sorrento has initiated cGMP manufacturing to produce 100,000 doses, expected to be available early next year, in anticipation of a potential EUA.</li>\n</ul>\n<p>SAN DIEGO, Nov. 09, 2020 (GLOBE NEWSWIRE) -- Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) announced today that it is filing an investigational new drug application (IND) for intravenous (IV) COVI-AMG (STI-2020) to treat COVID-19 patients with mild symptoms and to evaluate safety and pharmacokinetics in healthy volunteers.</p>\n<p>Sorrento has previously submitted an IND for COVI-GUARD™ (STI-1499), the parent antibody for COVI-AMG. That submission was cleared by the FDA in September. Sorrento has built on the knowledge from the prior IND requirements to file this new IND, including information and data about Sorrento’s affinity maturation process that further enhanced the potency of this antibody.</p>\n<p>As Sorrento previously announced, in preclinical studies, STI-2020 demonstrated a 100% neutralizing effect (both <em>in</em> <em>vitro</em> and <em>in vivo</em>) and at a very low dose prevented SARS-CoV-2 from infecting healthy cells and causing COVID-19-like disease in golden Syrian hamsters.</p>\n<p>The high potency of the antibody may potentially translate to more doses per bioreactor manufacturing run, lower cost per dose, and allow for rapid deployment and availability to patients. Sorrento has initiated cGMP manufacturing to produce 100,000 doses, expected to be available early next year, in anticipation of a potential EUA.</p>\n<p>In order to speed up development toward EUA submission, Sorrento is also planning on initiating dosing in a healthy population in order to rapidly generate safety and pharmacokinetic results.</p>\n<p>The STI-2020 antibody has been evaluated in preclinical studies against multiple strains of SARS-CoV-2, including the highly contagious D614G variant, the current dominant strain globally.</p>\n<p>The STI-2020 antibody has been engineered and demonstrated in preclinical studies to avoid ADE (antibody-dependent enhancement) which may be associated with the serious side effects of some other neutralizing antibodies and vaccines.</p>\n<p>More information about the phase 1 clinical trial can be found on www.clinicaltrials.gov (NCT# NCT04584697).</p>\n<p><strong>About Sorrento Therapeutics, Inc.  </strong><br/>Sorrento is a clinical stage, antibody-centric, biopharmaceutical company developing new therapies to treat cancers. Sorrento's multimodal, multipronged approach to fighting cancer is made possible by its extensive immuno-oncology platforms, including key assets such as fully human antibodies (\"G-MAB™ library\"), clinical stage immuno-cellular therapies (\"CAR-T\", \"DAR-T™\"), antibody-drug conjugates (\"ADCs\"), and clinical stage oncolytic virus (\"Seprehvir<sup>®</sup>\"). Sorrento is also developing potential antiviral therapies and vaccines against coronaviruses, including COVI-GUARD™, COVI-AMG™, COVI-SHIELD™ and COVI-DROPS™; and diagnostic test solutions, including COVI-TRACK™, COVI-STIX™ and COVI-TRACE™.</p>\n<p>Sorrento's commitment to life-enhancing therapies for patients is also demonstrated by our effort to advance a first-in-class (TRPV1 agonist) non-opioid pain management small molecule, resiniferatoxin (\"RTX\"), and SP-102 (10 mg, dexamethasone sodium phosphate viscous gel) (SEMDEXA™), a novel, viscous gel formulation of a widely used corticosteroid for epidural injections to treat lumbosacral radicular pain, or sciatica, and to commercialize ZTlido® (lidocaine topical system) 1.8% for the treatment of post-herpetic neuralgia. RTX has completed a phase IB trial for intractable pain associated with cancer and a phase 1B trial in osteoarthritis patients.  SEMDEXA is in a pivotal Phase 3 trial for the treatment of lumbosacral radicular pain, or sciatica. ZTlido® was approved by the FDA on February 28, 2018.</p>\n<p>For more information, visit <u>www.sorrentotherapeutics.com</u></p>\n<p><strong>Forward-Looking Statements</strong><br/>This press release and any statements made for and during any presentation or meeting contain forward-looking statements related to Sorrento Therapeutics, Inc., under the safe harbor provisions of Section 21E of the Private Securities Litigation Reform Act of 1995 and subject to risks and uncertainties that could cause actual results to differ materially from those projected. Forward-looking statements include statements regarding the potency and potential neutralizing profile of STI-2020 and the impact on SARS-CoV-2; the preclinical testing of STI-2020; the safety, pharmacokinetics and efficacy of STI-2020; the potential for STI-2020 to avoid antibody-dependent enhancement side effects; the expectation of the commencement of any pivotal trials for STI-2020; the potential receipt of an EUA for STI-2020 and expected timing for any receipt thereof; the expected availability of doses of STI-2020 and the timing thereof; the belief that the IND addresses all questions and recommendations from the FDA; the predictive value of the animal model used in preclinical studies; the proposed dosages in the phase 1 clinical trial; the potential potency of STI-2020; the expected effective dose in humans; the expected administration method of STI-2020; the potentially faster manufacturing speed, availability and potential lower cost for STI-2020; and Sorrento's potential position in the antiviral industry. Risks and uncertainties that could cause our actual results to differ materially and adversely from those expressed in our forward-looking statements, include, but are not limited to: risks related to Sorrento's and its subsidiaries', affiliates' and partners' technologies and prospects and collaborations with partners, including, but not limited to risks related to conducting pre-clinical studies and seeking IND regulatory approval for STI-2020; conducting and receiving results of clinical trials for STI-2020; the clinical and commercial success of STI-2020 against preventing and treating SARS-CoV-2 virus infections; the viability and success of STI-2020 in anti-viral therapeutic areas, including coronaviruses; clinical development risks, including risks in the progress, timing, cost, and results of clinical trials and product development programs; risk of difficulties or delays in obtaining regulatory approvals; risks that clinical study results may not meet any or all endpoints of a clinical study and that any data generated from such studies may not support a regulatory submission or approval; risks that prior test results may not be replicated in future studies and trials; risks of manufacturing and supplying drug product; risks related to leveraging the expertise of its employees, subsidiaries, affiliates and partners to assist the company in the execution of its COVID-19 therapeutic product candidates strategies; risks related to the global impact of COVID-19; and other risks that are described in Sorrento's most recent periodic reports filed with the Securities and Exchange Commission, including Sorrento's Annual Report on Form 10-K for the year ended December 31, 2019, and subsequent Quarterly Reports on Form 10-Q filed with the Securities and Exchange Commission, including the risk factors set forth in those filings. Investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release and we undertake no obligation to update any forward-looking statement in this press release except as required by law.</p>\n<p><strong><u>Contact</u></strong><br/>Alexis Nahama, DVM (SVP Corporate Development)<br/>Email: <u>mediarelations@sorrentotherapeutics.com</u></p>\n<p>Sorrento® and the Sorrento logo are registered trademarks of Sorrento Therapeutics, Inc.<br/>G-MAB™, COVI-GUARD<sup>TM</sup>, COVI-AMG™, COVI-SHIELD™, COVIDTRAP™, T-VIVA-19™, COVI-MAB™, ACE-MAB<sup>TM</sup>, COVI-DROPS<sup>TM</sup>, COVI-TRACK™, COVI-TRACE™, COVI-STIX™, and COVI-MOBILE™ are trademarks of Sorrento Therapeutics, Inc.</p>\n<p>ZTlido® is a trademark owned by Scilex Pharmaceuticals Inc.<br/>All other trademarks are the property of their respective owners. <br/>© 2020 Sorrento Therapeutics, Inc. All Rights Reserved.</p>\n<br/>\n<img height=\"1\" src=\"https://ml.globenewswire.com/release/track/304c722a-046e-41c0-94e8-d4603ebf6fd4\" width=\"1\"/></body></html>","source":"yahoofinance","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Sorrento Announces FDA IND Filing Today for COVI-AMG Neutralizing and High Potency Antibody Against SARS-CoV-2</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; 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}\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nSorrento Announces FDA IND Filing Today for COVI-AMG Neutralizing and High Potency Antibody Against SARS-CoV-2\n</h2>\n\n<h4 class=\"meta\">\n\n\n2020-11-09 22:00 GMT+8&nbsp;&nbsp;&nbsp;<a href=https://finance.yahoo.com/news/sorrento-announces-fda-ind-filing-140000531.html><strong>GlobeNewswire</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>IND filing today for STI-2020 (COVI-AMG™) for the treatment of COVID-19 in patients with mild symptoms and a separate safety and pharmacokinetic study in healthy volunteers.\nThese initial trials are ...</p>\n\n<a href=\"https://finance.yahoo.com/news/sorrento-announces-fda-ind-filing-140000531.html\">Web Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://s.yimg.com/uu/api/res/1.2/PoKGHRAaEjCoeUQ7jQhw4g--~B/aD05MzM7dz0yNjU3O2FwcGlkPXl0YWNoeW9u/https://s.yimg.com/uu/api/res/1.2/0La.lfx3M.BOH5N06.8hng--~B/aD05MzM7dz0yNjU3O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/globenewswire.com/04f9f4e64b77331b9d9868e002a03144","relate_stocks":{},"source_url":"https://finance.yahoo.com/news/sorrento-announces-fda-ind-filing-140000531.html","is_english":true,"share_image_url":"https://static.laohu8.com/5f26f4a48f9cb3e29be4d71d3ba8c038","article_id":"2082718698","content_text":"IND filing today for STI-2020 (COVI-AMG™) for the treatment of COVID-19 in patients with mild symptoms and a separate safety and pharmacokinetic study in healthy volunteers.\nThese initial trials are expected to be followed by pivotal trials with a goal of potentially receiving an EUA (Emergency Use Authorization).\nAnimal model data (golden Syrian hamsters infected with SARS-CoV-2) demonstrated a highly effective neutralizing profile.\nThis antibody has been engineered for ultra-high potency, with an expected effective dose in humans to be much lower than current known antibodies being assessed by others in active trials, which would allow for a simple IV-push administration that is suitable in the outpatient setting.\nThis antibody has been engineered and validated in preclinical studies to avoid antibody-dependent enhancement (ADE) to potentially increase the safety profile.\nAdditional in vitro experiments demonstrated the complete virus neutralizing property of STI-2020 against the highly contagious D614G SARS-CoV-2 variant.\nSorrento has initiated cGMP manufacturing to produce 100,000 doses, expected to be available early next year, in anticipation of a potential EUA.\n\nSAN DIEGO, Nov. 09, 2020 (GLOBE NEWSWIRE) -- Sorrento Therapeutics, Inc. (Nasdaq: SRNE, “Sorrento”) announced today that it is filing an investigational new drug application (IND) for intravenous (IV) COVI-AMG (STI-2020) to treat COVID-19 patients with mild symptoms and to evaluate safety and pharmacokinetics in healthy volunteers.\nSorrento has previously submitted an IND for COVI-GUARD™ (STI-1499), the parent antibody for COVI-AMG. That submission was cleared by the FDA in September. Sorrento has built on the knowledge from the prior IND requirements to file this new IND, including information and data about Sorrento’s affinity maturation process that further enhanced the potency of this antibody.\nAs Sorrento previously announced, in preclinical studies, STI-2020 demonstrated a 100% neutralizing effect (both in vitro and in vivo) and at a very low dose prevented SARS-CoV-2 from infecting healthy cells and causing COVID-19-like disease in golden Syrian hamsters.\nThe high potency of the antibody may potentially translate to more doses per bioreactor manufacturing run, lower cost per dose, and allow for rapid deployment and availability to patients. Sorrento has initiated cGMP manufacturing to produce 100,000 doses, expected to be available early next year, in anticipation of a potential EUA.\nIn order to speed up development toward EUA submission, Sorrento is also planning on initiating dosing in a healthy population in order to rapidly generate safety and pharmacokinetic results.\nThe STI-2020 antibody has been evaluated in preclinical studies against multiple strains of SARS-CoV-2, including the highly contagious D614G variant, the current dominant strain globally.\nThe STI-2020 antibody has been engineered and demonstrated in preclinical studies to avoid ADE (antibody-dependent enhancement) which may be associated with the serious side effects of some other neutralizing antibodies and vaccines.\nMore information about the phase 1 clinical trial can be found on www.clinicaltrials.gov (NCT# NCT04584697).\nAbout Sorrento Therapeutics, Inc.  Sorrento is a clinical stage, antibody-centric, biopharmaceutical company developing new therapies to treat cancers. Sorrento's multimodal, multipronged approach to fighting cancer is made possible by its extensive immuno-oncology platforms, including key assets such as fully human antibodies (\"G-MAB™ library\"), clinical stage immuno-cellular therapies (\"CAR-T\", \"DAR-T™\"), antibody-drug conjugates (\"ADCs\"), and clinical stage oncolytic virus (\"Seprehvir®\"). Sorrento is also developing potential antiviral therapies and vaccines against coronaviruses, including COVI-GUARD™, COVI-AMG™, COVI-SHIELD™ and COVI-DROPS™; and diagnostic test solutions, including COVI-TRACK™, COVI-STIX™ and COVI-TRACE™.\nSorrento's commitment to life-enhancing therapies for patients is also demonstrated by our effort to advance a first-in-class (TRPV1 agonist) non-opioid pain management small molecule, resiniferatoxin (\"RTX\"), and SP-102 (10 mg, dexamethasone sodium phosphate viscous gel) (SEMDEXA™), a novel, viscous gel formulation of a widely used corticosteroid for epidural injections to treat lumbosacral radicular pain, or sciatica, and to commercialize ZTlido® (lidocaine topical system) 1.8% for the treatment of post-herpetic neuralgia. RTX has completed a phase IB trial for intractable pain associated with cancer and a phase 1B trial in osteoarthritis patients.  SEMDEXA is in a pivotal Phase 3 trial for the treatment of lumbosacral radicular pain, or sciatica. ZTlido® was approved by the FDA on February 28, 2018.\nFor more information, visit www.sorrentotherapeutics.com\nForward-Looking StatementsThis press release and any statements made for and during any presentation or meeting contain forward-looking statements related to Sorrento Therapeutics, Inc., under the safe harbor provisions of Section 21E of the Private Securities Litigation Reform Act of 1995 and subject to risks and uncertainties that could cause actual results to differ materially from those projected. Forward-looking statements include statements regarding the potency and potential neutralizing profile of STI-2020 and the impact on SARS-CoV-2; the preclinical testing of STI-2020; the safety, pharmacokinetics and efficacy of STI-2020; the potential for STI-2020 to avoid antibody-dependent enhancement side effects; the expectation of the commencement of any pivotal trials for STI-2020; the potential receipt of an EUA for STI-2020 and expected timing for any receipt thereof; the expected availability of doses of STI-2020 and the timing thereof; the belief that the IND addresses all questions and recommendations from the FDA; the predictive value of the animal model used in preclinical studies; the proposed dosages in the phase 1 clinical trial; the potential potency of STI-2020; the expected effective dose in humans; the expected administration method of STI-2020; the potentially faster manufacturing speed, availability and potential lower cost for STI-2020; and Sorrento's potential position in the antiviral industry. Risks and uncertainties that could cause our actual results to differ materially and adversely from those expressed in our forward-looking statements, include, but are not limited to: risks related to Sorrento's and its subsidiaries', affiliates' and partners' technologies and prospects and collaborations with partners, including, but not limited to risks related to conducting pre-clinical studies and seeking IND regulatory approval for STI-2020; conducting and receiving results of clinical trials for STI-2020; the clinical and commercial success of STI-2020 against preventing and treating SARS-CoV-2 virus infections; the viability and success of STI-2020 in anti-viral therapeutic areas, including coronaviruses; clinical development risks, including risks in the progress, timing, cost, and results of clinical trials and product development programs; risk of difficulties or delays in obtaining regulatory approvals; risks that clinical study results may not meet any or all endpoints of a clinical study and that any data generated from such studies may not support a regulatory submission or approval; risks that prior test results may not be replicated in future studies and trials; risks of manufacturing and supplying drug product; risks related to leveraging the expertise of its employees, subsidiaries, affiliates and partners to assist the company in the execution of its COVID-19 therapeutic product candidates strategies; risks related to the global impact of COVID-19; and other risks that are described in Sorrento's most recent periodic reports filed with the Securities and Exchange Commission, including Sorrento's Annual Report on Form 10-K for the year ended December 31, 2019, and subsequent Quarterly Reports on Form 10-Q filed with the Securities and Exchange Commission, including the risk factors set forth in those filings. Investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release and we undertake no obligation to update any forward-looking statement in this press release except as required by law.\nContactAlexis Nahama, DVM (SVP Corporate Development)Email: mediarelations@sorrentotherapeutics.com\nSorrento® and the Sorrento logo are registered trademarks of Sorrento Therapeutics, Inc.G-MAB™, COVI-GUARDTM, COVI-AMG™, COVI-SHIELD™, COVIDTRAP™, T-VIVA-19™, COVI-MAB™, ACE-MABTM, COVI-DROPSTM, COVI-TRACK™, COVI-TRACE™, COVI-STIX™, and COVI-MOBILE™ are trademarks of Sorrento Therapeutics, Inc.\nZTlido® is a trademark owned by Scilex Pharmaceuticals Inc.All other trademarks are the property of their respective owners. © 2020 Sorrento Therapeutics, Inc. All Rights Reserved.","news_type":1},"isVote":1,"tweetType":1,"viewCount":893,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":308810328,"gmtCreate":1603922855464,"gmtModify":1703831264929,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"有够胆的就是接飞刀最好的时间了。","listText":"有够胆的就是接飞刀最好的时间了。","text":"有够胆的就是接飞刀最好的时间了。","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/308810328","isVote":1,"tweetType":1,"viewCount":1798,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":977967649,"gmtCreate":1601400234581,"gmtModify":1703824225490,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>这次上升的更稳","listText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>这次上升的更稳","text":"$Sorrento Therapeutics Inc.(SRNE)$这次上升的更稳","images":[{"img":"https://static.tigerbbs.com/ee5683f2e56fa34b6227645e925a80b5","width":"1080","height":"1920"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":3,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/977967649","isVote":1,"tweetType":1,"viewCount":1859,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":975454378,"gmtCreate":1600807585594,"gmtModify":1703822541962,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>看最后一个多小时的增量，你就应该知道上车或下车。","listText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>看最后一个多小时的增量，你就应该知道上车或下车。","text":"$Sorrento Therapeutics 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href=\"https://laohu8.com/S/NVAX\">$诺瓦瓦克斯医药(NVAX)$</a>这股估计得百元才能消停","listText":"<a 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17:08","market":"us","language":"zh","title":"Facebook董事会大洗牌，看小扎如何控制社交帝国","url":"https://stock-news.laohu8.com/highlight/detail?id=1166051331","media":"硅谷封面","summary":"编者按：Facebook首席执行官马克 扎克伯格(Mark Zuckerberg)相对低调，长期以来总是依靠首席运营官桑德伯格来处理政策和运营问题，依靠首席产品官考克斯来监管平台的许多重大变化。但随着","content":"<p><b>编者按：</b><a href=\"https://laohu8.com/S/FB\">Facebook</a>首席执行官马克 扎克伯格(Mark Zuckerberg)相对低调，长期以来总是依靠首席运营官桑德伯格来处理政策和运营问题，依靠首席产品官考克斯来监管平台的许多重大变化。但随着Facebook在虚假信息传播、用户数据监管失之于宽、公司竞争方式等诸多方面频频遭受非议，这位35岁的社交媒体大亨开始走上前台，通过董事会大洗牌获得对公司管理的更多控制权，并试图通过公司在应对疫情中的一系列高调举措扭转公众印象。</p>\n<p><img src=\"https://static.tigerbbs.com/24496c8880d643fe0a2edf0bde6d0c1e\"></p>\n<p><b>以下为文章正文：</b></p>\n<p>去年12月，社交媒体公司Facebook的高管们齐聚在马克 扎克伯格(Mark Zuckerberg)位于夏威夷考艾岛(Kauai)的海滨别墅。在这座占地700多英亩的私人宅邸内，扎克伯格主持召开了一次非同寻常的董事会，讨论在公司经历多年动荡之后该如何调整运营方向。</p>\n<p>据知情人士透露，会上确定的一些变化让很多人始料未及。</p>\n<p>几个月后Facebook宣布两位董事离职，并将扎克伯格的一位老朋友吸收进公司董事会。过去两年中，扎克伯格为巩固自身决策权而采取了一系列行动，这些举措也标志着其行动达到了高峰。扎克伯格还指导Facebook在应对新型冠状病毒疫情方面开展了一系列高调活动，将自己置于媒体的聚光灯下。</p>\n<p>其带来的结果是，这位Facebook首席执行官和董事长比过去几年更积极、更明显地担起自己在管理公司方面的职责。</p>\n<p>在此之前的三年多时间中，Facebook一直因在虚假信息传播、用户数据监管失之于宽、公司竞争方式等诸多方面存在的问题而引发各种争议。目前还不能确定，扎克伯格对Facebook的重新定位以及自己在公司高层的角色转变，是否能给Facebook的声誉带来持久转变。</p>\n<p>长期任职的董事以及过去两年中几位长期副手的离职，意味着扎克伯格正在没有关键顾问、或许没人帮忙发现潜在陷阱的情况度过这一时期。</p>\n<p>扎克伯格拒绝置评。Facebook的一位发言人说：“Facebook的根本使命是建立联系，而联系从来没有像现在这样如此重要。”</p>\n<p>从某种程度上而言，扎克伯格是按照他在2017年2月发布的近6000字宣言来定位Facebook。在此之中他设想Facebook是“社会基础设施”，可以帮助解决疾病等全球问题。然而，这个雄心勃勃的愿景却被外部势力操纵平台、剑桥分析公司不当访问用户数据等嘈杂声音掩盖了。</p>\n<p>不少联邦以及州层面的政府机构一直在调查Facebook。美国联邦贸易委员会（FCC）于2018年开始调查公司的用户数据问题，去年7月与Facebook达成了创纪录的50亿美元和解协议。</p>\n<p><img src=\"https://static.tigerbbs.com/bc43af59629d1d16d120237fe83b2e41\"><i>Facebook应用</i></p>\n<p>长期以来，扎克伯格一直依靠首席运营官、事实上的副手雪莉·桑德伯格(Sheryl Sandberg)来处理政策和运营问题，依靠首席产品官、老朋友克里斯·考克斯(Chris Cox)来监管平台的许多重大调整和变化。</p>\n<p>扎克伯格在2018年担负起了公司战时领导人的角色，不仅常常需要迅速采取行动，有时还需要单方作出决策。他宣布了一系列将Facebook引向新方向的产品，从2019年3月发布的声明开始，公司着重强调私有加密信息，而不是出名的公开信息。</p>\n<p>扎克伯格说，新的关注重点将使Facebook更像家中客厅而非城镇广场。这也让扎克伯格在Instagram和WhatsApp上获得了新的管理权，此前他曾承诺要独立运营这两家公司。</p>\n<p>消息公布后不久，曾被视为扎克伯格潜在继任者的考克斯出人意料辞职。此时距离考克斯入职Facebook已经有13年的时间。</p>\n<p>据知情人士透露，考克斯担心，向加密技术的转变会妨碍对恐怖主义和贩卖儿童等犯罪活动的调查。</p>\n<p>去年4月，Facebook披露两名长期独立董事将离开董事会。他们分别是Netflix 首席执行官里德·哈斯廷斯(Reed Hastings)和前投资银行家、克林顿政府官员厄斯金·鲍尔斯(Erskine Bowles)。</p>\n<p>据一位直接了解鲍尔斯的人士透露，鲍尔斯离职后曾私下批评Facebook的领导层没有听取他在政府政策方面的建议，而这正是鲍尔斯的专长所在。鲍尔斯拒绝置评。哈斯廷斯的发言人也没有回复置评请求。</p>\n<p>去年10月Facebook表示，自2015年6月起担任首席独立董事的苏珊 德斯蒙德-赫尔曼(Susan Desmond-Hellmann)将离开董事会。Facebook援引德斯蒙德-赫尔曼的话说，其离职是出于身体健康和家庭原因。一位知情人士则说，德斯蒙德-赫尔曼私下向一些人表示，自己离开Facebook的部分原因是她认为董事会运作不正常，而且Facebook管理层不会考虑董事会的意见。</p>\n<p>今年4月份，德斯蒙德-赫尔曼加入了制药巨头辉瑞公司的董事会。记者上周联系到德斯蒙德-赫尔曼请她置评有关离职Facebook的问题。她说Facebook的新闻稿是准确的，并对相关人士的描述提出了质疑。</p>\n<p><b>掌权</b></p>\n<p>据知情人士透露，扎克伯格去年12月在位于夏威夷的私人宅邸主持召开董事会会议，希望借助当地优美环境缓和一下紧张局势。</p>\n<p>会上董事和高管们审视了公司所面临的越来越多监管问题，包括Facebook将如何应对涉及要求复杂的美国联邦贸易委员会和解协议。这些人士说，他们讨论了公司战略、文化和治理方面的诸多问题。其中一位知情人士说，一些人在结束会议时感觉情况可能会好转。</p>\n<p>然而在下个月的财报电话会议上，扎克伯格似乎已经开始从道歉作出改变。他说，Facebook过去没有明确表达过自己的观点，“因为我们担心冒犯别人”。“我下一个十年的目标不是让人喜欢，而是让人理解。”</p>\n<p>扎克伯格需要赢得更多的董事会支持。知情人士称，他一直与任职时间最长的董事之一、风险投资大师马克 安德森(Marc Andreessen)意见不合。其中一名知情人士说，在Facebook努力遵守美国联邦贸易委员会和解协议的过程中，两人“各执一词、互不相让”。</p>\n<p>知情人士说，安德森向一些人表露出自己对Facebook是否有能力并愿意遵守这些条款感到失望的态度，并考虑离开董事会。安德森-霍洛维茨基金的发言人拒绝置评。</p>\n<p>Facebook发言人说，安德森从未怀疑过公司遵守和解协议的能力或承诺。</p>\n<p>去年春天，<a href=\"https://laohu8.com/S/PYPL\">PayPal</a>高管佩吉 阿尔福德(Peggy Alford)加入了Facebook董事会。阿尔福德曾在扎克伯格手下担任基金会“陈-扎克伯格行动”(Chan Zuckerberg Initiative)的首席财务官。今年2月份，扎克伯格在董事会获得了更多支持，其老朋友、云软件公司Dropbox首席执行官德鲁 休斯顿(Drew Houston)也加入进来。</p>\n<p>休斯顿的发言人拒绝置评。阿尔福德没有回复记者的置评请求。</p>\n<p>当新型冠状病毒疫情在美国蔓延开来时，扎克伯格迅速动员起整个Facebook。3月2日，他召集公司业务和产品部门的高级代表开会讨论应对措施。</p>\n<p>知情人士说，扎克伯格和其他高层领导人认为Facebook有机会发挥重要作用。参与讨论的一名人士表示，他们要求高管们想出一个“有助于改变公众对Facebook看法”的好主意。</p>\n<p>其中一个想法是开展一场声势浩大的广告宣传活动，向Facebook用户打出这样的口号：“如果我们能找到彼此，我们就永远不会迷路。”</p>\n<p>公司发言人则反驳了扎克伯格曾鼓励参会代表们将Facebook反应视为一次公关良机的说辞。这位发言人表示：“任何声誉提升都将是这项工作的副产品，而不是驱动因素。”</p>\n<p>3月初的一个周末，20名高级管理人员又在扎克伯格位于加州帕洛阿尔托(Palo Alto)的住所内参与了一个名为新型冠状病毒信息中心(coronavirus information hub)的项目，其中包括诸如提醒保持社交距离等功能。几天之内这个项目就上线了。</p>\n<p><b>调整</b></p>\n<p>3月中旬，Facebook宣布<a href=\"https://laohu8.com/S/AXP\">美国运通</a>(American <a href=\"https://laohu8.com/S/EXPR\">Express</a>)前首席执行官肯尼斯 切诺特(Kenneth Chenault)将离开董事会。</p>\n<p>他和扎克伯格一度关系密切。据一名熟悉二人关系的人士透露，在2018年2月加入董事会之前，扎克伯格有段时间每周都会给切诺特打电话征求意见，把他当作懂得如何管理大型机构的“善良叔叔”。</p>\n<p><img src=\"https://static.tigerbbs.com/29939166c6d49fe6c67f294c0dc3e4c0\"><i>Facebook董事会成员的调整变化</i></p>\n<p>但现在切诺特已经幡然醒悟。据知情人士透露，在加入Facebook后不久，切诺特就试图创建一个专门研究Facebook问题的外部咨询小组，并绕开扎克伯格直接向董事会提交报告。结果董事会里的其他人提出反对意见，这个主意最终落空了。</p>\n<p><img src=\"https://static.tigerbbs.com/c9c1cb28f28f06a7ad9d0b0cf7863d2b\"><i>美国运通前首席执行官肯尼斯 切诺特(Kenneth Chenault)</i></p>\n<p>在Facebook宣布离职的声明中，切诺特说自己之所以离职，是因为能加入<a href=\"https://laohu8.com/S/BRK.A\">伯克希尔</a>哈撒韦公司董事会，这一机会千载难逢。</p>\n<p>大约两周后，Facebook表示齐恩茨也将离开董事会，腾出更多时间处理自家业务。知情人士说，数月来切诺特和齐恩茨都对整个管理层以及公司处理错误信息的方式感到不满。</p>\n<p>今年3月份，Facebook任命前美国副财长、商人罗伯特·M·金米特(Robert M. Kimmitt)为首席独立董事。麦肯锡公司前高管南希·基耶弗(Nancy Killefer)和<a href=\"https://laohu8.com/S/EL\">雅诗兰黛</a>首席财务官特蕾西·特拉维斯(Tracey Travis)也相继加入董事会。目前董事会有11名成员，股东投票定于5月份举行。</p>\n<p>至此，Facebook在2019年初的九名公司董事中只有4人留任。他们分别是扎克伯格、桑德伯格、安德森和风险投资家彼得·蒂尔(Peter Thiel)。</p>\n<p>董事会的调整并没有影响到扎克伯格的其他举措。Facebook宣布向小企业提供1亿美元的援助，Facebook广告销售额中很大一部分都来自小企业。另外公司还将向新闻行业提供1亿美元的援助。</p>\n<p><img src=\"https://static.tigerbbs.com/c630f91cc1c58ce03a38cf6838bd97f0\"><i>今年2月份，扎克伯格在德国慕尼黑举行的一次会议上</i></p>\n<p>4月下旬，Facebook进行了规模最大的海外投资，斥资近60亿美元收购印度一家电信运营商的股份。扎克伯格长期以来一直试图在印度扩张业务。随后，扎克伯格又宣布推出一项名为Facebook Rooms的视频聊天服务，与<a href=\"https://laohu8.com/S/ZM\">Zoom</a>进行竞争。“我们将在相当长的一段时间内应对这种情况，”扎克伯格这样说。</p>","source":"GGFM","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Facebook董事会大洗牌，看小扎如何控制社交帝国</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nFacebook董事会大洗牌，看小扎如何控制社交帝国\n</h2>\n\n<h4 class=\"meta\">\n\n\n2020-05-09 17:08 北京时间&nbsp;&nbsp;&nbsp;<a href=https://new.qq.com/omn/20200508/20200508A0J5UV00.html><strong>硅谷封面</strong></a>\n\n\n</h4>\n\n</header>\n<article>\n<div>\n<p>编者按：Facebook首席执行官马克 扎克伯格(Mark Zuckerberg)相对低调，长期以来总是依靠首席运营官桑德伯格来处理政策和运营问题，依靠首席产品官考克斯来监管平台的许多重大变化。但随着Facebook在虚假信息传播、用户数据监管失之于宽、公司竞争方式等诸多方面频频遭受非议，这位35岁的社交媒体大亨开始走上前台，通过董事会大洗牌获得对公司管理的更多控制权，并试图通过公司在应对疫情中的...</p>\n\n<a href=\"https://new.qq.com/omn/20200508/20200508A0J5UV00.html\">Web Link</a>\n\n</div>\n\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/9e651bf4e105f2ad0a73eeb437e1d161","relate_stocks":{},"source_url":"https://new.qq.com/omn/20200508/20200508A0J5UV00.html","is_english":false,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1166051331","content_text":"编者按：Facebook首席执行官马克 扎克伯格(Mark Zuckerberg)相对低调，长期以来总是依靠首席运营官桑德伯格来处理政策和运营问题，依靠首席产品官考克斯来监管平台的许多重大变化。但随着Facebook在虚假信息传播、用户数据监管失之于宽、公司竞争方式等诸多方面频频遭受非议，这位35岁的社交媒体大亨开始走上前台，通过董事会大洗牌获得对公司管理的更多控制权，并试图通过公司在应对疫情中的一系列高调举措扭转公众印象。\n\n以下为文章正文：\n去年12月，社交媒体公司Facebook的高管们齐聚在马克 扎克伯格(Mark Zuckerberg)位于夏威夷考艾岛(Kauai)的海滨别墅。在这座占地700多英亩的私人宅邸内，扎克伯格主持召开了一次非同寻常的董事会，讨论在公司经历多年动荡之后该如何调整运营方向。\n据知情人士透露，会上确定的一些变化让很多人始料未及。\n几个月后Facebook宣布两位董事离职，并将扎克伯格的一位老朋友吸收进公司董事会。过去两年中，扎克伯格为巩固自身决策权而采取了一系列行动，这些举措也标志着其行动达到了高峰。扎克伯格还指导Facebook在应对新型冠状病毒疫情方面开展了一系列高调活动，将自己置于媒体的聚光灯下。\n其带来的结果是，这位Facebook首席执行官和董事长比过去几年更积极、更明显地担起自己在管理公司方面的职责。\n在此之前的三年多时间中，Facebook一直因在虚假信息传播、用户数据监管失之于宽、公司竞争方式等诸多方面存在的问题而引发各种争议。目前还不能确定，扎克伯格对Facebook的重新定位以及自己在公司高层的角色转变，是否能给Facebook的声誉带来持久转变。\n长期任职的董事以及过去两年中几位长期副手的离职，意味着扎克伯格正在没有关键顾问、或许没人帮忙发现潜在陷阱的情况度过这一时期。\n扎克伯格拒绝置评。Facebook的一位发言人说：“Facebook的根本使命是建立联系，而联系从来没有像现在这样如此重要。”\n从某种程度上而言，扎克伯格是按照他在2017年2月发布的近6000字宣言来定位Facebook。在此之中他设想Facebook是“社会基础设施”，可以帮助解决疾病等全球问题。然而，这个雄心勃勃的愿景却被外部势力操纵平台、剑桥分析公司不当访问用户数据等嘈杂声音掩盖了。\n不少联邦以及州层面的政府机构一直在调查Facebook。美国联邦贸易委员会（FCC）于2018年开始调查公司的用户数据问题，去年7月与Facebook达成了创纪录的50亿美元和解协议。\nFacebook应用\n长期以来，扎克伯格一直依靠首席运营官、事实上的副手雪莉·桑德伯格(Sheryl Sandberg)来处理政策和运营问题，依靠首席产品官、老朋友克里斯·考克斯(Chris Cox)来监管平台的许多重大调整和变化。\n扎克伯格在2018年担负起了公司战时领导人的角色，不仅常常需要迅速采取行动，有时还需要单方作出决策。他宣布了一系列将Facebook引向新方向的产品，从2019年3月发布的声明开始，公司着重强调私有加密信息，而不是出名的公开信息。\n扎克伯格说，新的关注重点将使Facebook更像家中客厅而非城镇广场。这也让扎克伯格在Instagram和WhatsApp上获得了新的管理权，此前他曾承诺要独立运营这两家公司。\n消息公布后不久，曾被视为扎克伯格潜在继任者的考克斯出人意料辞职。此时距离考克斯入职Facebook已经有13年的时间。\n据知情人士透露，考克斯担心，向加密技术的转变会妨碍对恐怖主义和贩卖儿童等犯罪活动的调查。\n去年4月，Facebook披露两名长期独立董事将离开董事会。他们分别是Netflix 首席执行官里德·哈斯廷斯(Reed Hastings)和前投资银行家、克林顿政府官员厄斯金·鲍尔斯(Erskine Bowles)。\n据一位直接了解鲍尔斯的人士透露，鲍尔斯离职后曾私下批评Facebook的领导层没有听取他在政府政策方面的建议，而这正是鲍尔斯的专长所在。鲍尔斯拒绝置评。哈斯廷斯的发言人也没有回复置评请求。\n去年10月Facebook表示，自2015年6月起担任首席独立董事的苏珊 德斯蒙德-赫尔曼(Susan Desmond-Hellmann)将离开董事会。Facebook援引德斯蒙德-赫尔曼的话说，其离职是出于身体健康和家庭原因。一位知情人士则说，德斯蒙德-赫尔曼私下向一些人表示，自己离开Facebook的部分原因是她认为董事会运作不正常，而且Facebook管理层不会考虑董事会的意见。\n今年4月份，德斯蒙德-赫尔曼加入了制药巨头辉瑞公司的董事会。记者上周联系到德斯蒙德-赫尔曼请她置评有关离职Facebook的问题。她说Facebook的新闻稿是准确的，并对相关人士的描述提出了质疑。\n掌权\n据知情人士透露，扎克伯格去年12月在位于夏威夷的私人宅邸主持召开董事会会议，希望借助当地优美环境缓和一下紧张局势。\n会上董事和高管们审视了公司所面临的越来越多监管问题，包括Facebook将如何应对涉及要求复杂的美国联邦贸易委员会和解协议。这些人士说，他们讨论了公司战略、文化和治理方面的诸多问题。其中一位知情人士说，一些人在结束会议时感觉情况可能会好转。\n然而在下个月的财报电话会议上，扎克伯格似乎已经开始从道歉作出改变。他说，Facebook过去没有明确表达过自己的观点，“因为我们担心冒犯别人”。“我下一个十年的目标不是让人喜欢，而是让人理解。”\n扎克伯格需要赢得更多的董事会支持。知情人士称，他一直与任职时间最长的董事之一、风险投资大师马克 安德森(Marc Andreessen)意见不合。其中一名知情人士说，在Facebook努力遵守美国联邦贸易委员会和解协议的过程中，两人“各执一词、互不相让”。\n知情人士说，安德森向一些人表露出自己对Facebook是否有能力并愿意遵守这些条款感到失望的态度，并考虑离开董事会。安德森-霍洛维茨基金的发言人拒绝置评。\nFacebook发言人说，安德森从未怀疑过公司遵守和解协议的能力或承诺。\n去年春天，PayPal高管佩吉 阿尔福德(Peggy Alford)加入了Facebook董事会。阿尔福德曾在扎克伯格手下担任基金会“陈-扎克伯格行动”(Chan Zuckerberg Initiative)的首席财务官。今年2月份，扎克伯格在董事会获得了更多支持，其老朋友、云软件公司Dropbox首席执行官德鲁 休斯顿(Drew Houston)也加入进来。\n休斯顿的发言人拒绝置评。阿尔福德没有回复记者的置评请求。\n当新型冠状病毒疫情在美国蔓延开来时，扎克伯格迅速动员起整个Facebook。3月2日，他召集公司业务和产品部门的高级代表开会讨论应对措施。\n知情人士说，扎克伯格和其他高层领导人认为Facebook有机会发挥重要作用。参与讨论的一名人士表示，他们要求高管们想出一个“有助于改变公众对Facebook看法”的好主意。\n其中一个想法是开展一场声势浩大的广告宣传活动，向Facebook用户打出这样的口号：“如果我们能找到彼此，我们就永远不会迷路。”\n公司发言人则反驳了扎克伯格曾鼓励参会代表们将Facebook反应视为一次公关良机的说辞。这位发言人表示：“任何声誉提升都将是这项工作的副产品，而不是驱动因素。”\n3月初的一个周末，20名高级管理人员又在扎克伯格位于加州帕洛阿尔托(Palo Alto)的住所内参与了一个名为新型冠状病毒信息中心(coronavirus information hub)的项目，其中包括诸如提醒保持社交距离等功能。几天之内这个项目就上线了。\n调整\n3月中旬，Facebook宣布美国运通(American Express)前首席执行官肯尼斯 切诺特(Kenneth Chenault)将离开董事会。\n他和扎克伯格一度关系密切。据一名熟悉二人关系的人士透露，在2018年2月加入董事会之前，扎克伯格有段时间每周都会给切诺特打电话征求意见，把他当作懂得如何管理大型机构的“善良叔叔”。\nFacebook董事会成员的调整变化\n但现在切诺特已经幡然醒悟。据知情人士透露，在加入Facebook后不久，切诺特就试图创建一个专门研究Facebook问题的外部咨询小组，并绕开扎克伯格直接向董事会提交报告。结果董事会里的其他人提出反对意见，这个主意最终落空了。\n美国运通前首席执行官肯尼斯 切诺特(Kenneth Chenault)\n在Facebook宣布离职的声明中，切诺特说自己之所以离职，是因为能加入伯克希尔哈撒韦公司董事会，这一机会千载难逢。\n大约两周后，Facebook表示齐恩茨也将离开董事会，腾出更多时间处理自家业务。知情人士说，数月来切诺特和齐恩茨都对整个管理层以及公司处理错误信息的方式感到不满。\n今年3月份，Facebook任命前美国副财长、商人罗伯特·M·金米特(Robert M. Kimmitt)为首席独立董事。麦肯锡公司前高管南希·基耶弗(Nancy Killefer)和雅诗兰黛首席财务官特蕾西·特拉维斯(Tracey Travis)也相继加入董事会。目前董事会有11名成员，股东投票定于5月份举行。\n至此，Facebook在2019年初的九名公司董事中只有4人留任。他们分别是扎克伯格、桑德伯格、安德森和风险投资家彼得·蒂尔(Peter Thiel)。\n董事会的调整并没有影响到扎克伯格的其他举措。Facebook宣布向小企业提供1亿美元的援助，Facebook广告销售额中很大一部分都来自小企业。另外公司还将向新闻行业提供1亿美元的援助。\n今年2月份，扎克伯格在德国慕尼黑举行的一次会议上\n4月下旬，Facebook进行了规模最大的海外投资，斥资近60亿美元收购印度一家电信运营商的股份。扎克伯格长期以来一直试图在印度扩张业务。随后，扎克伯格又宣布推出一项名为Facebook Rooms的视频聊天服务，与Zoom进行竞争。“我们将在相当长的一段时间内应对这种情况，”扎克伯格这样说。","news_type":1},"isVote":1,"tweetType":1,"viewCount":336,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":927902949,"gmtCreate":1588688478181,"gmtModify":1704178070049,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"今天油股都在涨，不过得小心哦，开始涨跌不一了","listText":"今天油股都在涨，不过得小心哦，开始涨跌不一了","text":"今天油股都在涨，不过得小心哦，开始涨跌不一了","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":0,"commentSize":1,"repostSize":0,"link":"https://laohu8.com/post/927902949","isVote":1,"tweetType":1,"viewCount":510,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":924340697,"gmtCreate":1588237225619,"gmtModify":1704367039137,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"看来今年大选各方布局都是拼命把各自的饼画得又大又美","listText":"看来今年大选各方布局都是拼命把各自的饼画得又大又美","text":"看来今年大选各方布局都是拼命把各自的饼画得又大又美","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":2,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/924340697","isVote":1,"tweetType":1,"viewCount":448,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0},{"id":944493484,"gmtCreate":1597071442748,"gmtModify":1704214309276,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>我也成绩不错","listText":"<a href=\"https://laohu8.com/S/SRNE\">$Sorrento Therapeutics Inc.(SRNE)$</a>我也成绩不错","text":"$Sorrento Therapeutics Inc.(SRNE)$我也成绩不错","images":[{"img":"https://static.tigerbbs.com/d1c25d50891643ebcf0c1815243ee16b","width":"1080","height":"1920"}],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/944493484","isVote":1,"tweetType":1,"viewCount":954,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":1,"langContent":"CN","totalScore":0},{"id":924002462,"gmtCreate":1588162165556,"gmtModify":1704366655891,"author":{"id":"3542328439002885","authorId":"3542328439002885","name":"helen88","avatar":"https://static.laohu8.com/default-avatar.jpg","crmLevel":1,"crmLevelSwitch":0,"followedFlag":false,"idStr":"3542328439002885","authorIdStr":"3542328439002885"},"themes":[],"htmlText":"赌场是在困景中恢复最快的行业，一半本金在股市，一半就去赌场买一手大小[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;","listText":"赌场是在困景中恢复最快的行业，一半本金在股市，一半就去赌场买一手大小[龇牙]&nbsp;[龇牙]&nbsp;[龇牙]&nbsp;","text":"赌场是在困景中恢复最快的行业，一半本金在股市，一半就去赌场买一手大小[龇牙] [龇牙] [龇牙]","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":1,"commentSize":0,"repostSize":0,"link":"https://laohu8.com/post/924002462","isVote":1,"tweetType":1,"viewCount":195,"authorTweetTopStatus":1,"verified":2,"comments":[],"imageCount":0,"langContent":"CN","totalScore":0}],"lives":[]}