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2019-03-08

$Tonix Pharmaceuticals Holding Co(TNXP)$ 果断上

2018-10-05

$GTx(GTXI)$ 感觉今晚还能起来

2019-03-08

$GTx(GTXI)$ 后发制人还是很有意思

2018-09-22

$India Globalization Capital(IGC)$ 看这趋势明天还得走一波

2020-02-10

这篇文章不错，转发给大家看

抱歉，原内容已删除

2019-06-19

$Melinta Therapeutics, Inc.(MLNT)$ 有水平的庄

2019-03-08

$Tonix Pharmaceuticals Holding Co(TNXP)$ 不容易啊，总算加码速度了

2019-03-08

$Tonix Pharmaceuticals Holding Co(TNXP)$ 今天的股确实有点邪乎，考虑再三，还是选你吧

2019-03-07

$GTx(GTXI)$ 慢工出细活

2019-03-07

$GTx(GTXI)$ 后半场发力

去老虎APP查看更多动态

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21:12","market":"us","language":"zh","title":"VTV Therapeutics盘前暴涨85%，今日公布药物数据","url":"https://stock-news.laohu8.com/highlight/detail?id=1157125422","media":"老虎资讯综合","summary":"2月10日美股盘前，生物制药公司VTV Therapeutics$(VTVT)$暴涨85%。\n\n该公司周五表示，周一上午将公布第二期Simplici-T1试验第二部分的最新结果，该试验评估TTP399","content":"<p><span>2月10日美股盘前，生物制药公司VTV Therapeutics<a href=\"https://laohu8.com/S/VTVT\">$(VTVT)$</a>暴涨85%。</span></p>\n<p><img src=\"https://static.tigerbbs.com/b33f76b37c8eb11741cc9b945b2feaad\"></p>\n<p><span>该公司周五表示，周一上午将公布第二期Simplici-T1试验第二部分的最新结果，该试验评估TTP399为成人1型糖尿病患者胰岛素的口服辅助疗法。</span></p>\n<p><span>在2019年6月，该公司宣布了第二阶段研究的第一部分的积极结果，该部分显示HbA1c在统计学上显著下降，而没有增加酮症酸中毒或低血糖。在第一部分中，TTP 399的耐受性与治疗相似--总体上和系统器官类紧急不良事件的发生率相似。第一部分无严重不良事件报告，无糖尿病酮症酸中毒或严重低血糖的报告。</span></p>\n<p><span><b>关于TTP399。</b></span><span>葡萄糖激酶(GK)是葡萄糖代谢的关键调节因子，它的激活可以增加葡萄糖的利用率，进而降低血糖。TTP399是一种口服的GK激动剂，旨在通过仅针对肝脏中的GK激活来实现血糖控制，其作用机制不依赖于胰岛素。</span></p>\n<p><span>到目前为止，TTP399已经在12项临床试验中进行了研究，其中包括一项针对2型糖尿病患者的为期6个月的2b期试验，在该试验中，它显示出HbA1c持续、有意义的降低，耐受性良好，低血糖和高脂血症的发生率可以忽略不计，没有糖尿病酮症酸中毒的发生。</span></p>\n<p><span><b>关于Simplici-T1。</b></span><span>Simplici-T1是一项多中心、随机、双盲、适应性研究，评估TTP399作为成人T1D胰岛素治疗辅助药物的安全性和有效性。主要终点是第12周时HbA1c的变化。这项研究是在JDRF的支持下进行的，JDRF是资助1型糖尿病研究的领先全球组织。这项第二阶段的学习和确认研究在相同的方案下分两部分进行，以评估TTP399在经过多周胰岛素优化和安慰剂磨合期后每天给药12周以上的T1D患者的安全性和有效性。第一部分招募了19名同时接受胰岛素泵和CGMS治疗的患者。第二阶段-第一部分的阳性背线结果于2019年6月报告。第二部分招募了85名患者，他们使用胰岛素泵或每天多次注射胰岛素，没有使用CGM。</span></p>","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>VTV Therapeutics盘前暴涨85%，今日公布药物数据</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ 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padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nVTV Therapeutics盘前暴涨85%，今日公布药物数据\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/102\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\n<p class=\"h-name\">老虎资讯综合 </p>\n<p class=\"h-time\">2020-02-10 21:12</p>\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\n<p><span>2月10日美股盘前，生物制药公司VTV Therapeutics<a href=\"https://laohu8.com/S/VTVT\">$(VTVT)$</a>暴涨85%。</span></p>\n<p><img src=\"https://static.tigerbbs.com/b33f76b37c8eb11741cc9b945b2feaad\"></p>\n<p><span>该公司周五表示，周一上午将公布第二期Simplici-T1试验第二部分的最新结果，该试验评估TTP399为成人1型糖尿病患者胰岛素的口服辅助疗法。</span></p>\n<p><span>在2019年6月，该公司宣布了第二阶段研究的第一部分的积极结果，该部分显示HbA1c在统计学上显著下降，而没有增加酮症酸中毒或低血糖。在第一部分中，TTP 399的耐受性与治疗相似--总体上和系统器官类紧急不良事件的发生率相似。第一部分无严重不良事件报告，无糖尿病酮症酸中毒或严重低血糖的报告。</span></p>\n<p><span><b>关于TTP399。</b></span><span>葡萄糖激酶(GK)是葡萄糖代谢的关键调节因子，它的激活可以增加葡萄糖的利用率，进而降低血糖。TTP399是一种口服的GK激动剂，旨在通过仅针对肝脏中的GK激活来实现血糖控制，其作用机制不依赖于胰岛素。</span></p>\n<p><span>到目前为止，TTP399已经在12项临床试验中进行了研究，其中包括一项针对2型糖尿病患者的为期6个月的2b期试验，在该试验中，它显示出HbA1c持续、有意义的降低，耐受性良好，低血糖和高脂血症的发生率可以忽略不计，没有糖尿病酮症酸中毒的发生。</span></p>\n<p><span><b>关于Simplici-T1。</b></span><span>Simplici-T1是一项多中心、随机、双盲、适应性研究，评估TTP399作为成人T1D胰岛素治疗辅助药物的安全性和有效性。主要终点是第12周时HbA1c的变化。这项研究是在JDRF的支持下进行的，JDRF是资助1型糖尿病研究的领先全球组织。这项第二阶段的学习和确认研究在相同的方案下分两部分进行，以评估TTP399在经过多周胰岛素优化和安慰剂磨合期后每天给药12周以上的T1D患者的安全性和有效性。第一部分招募了19名同时接受胰岛素泵和CGMS治疗的患者。第二阶段-第一部分的阳性背线结果于2019年6月报告。第二部分招募了85名患者，他们使用胰岛素泵或每天多次注射胰岛素，没有使用CGM。</span></p>\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"https://static.tigerbbs.com/f874ded00c644297784368a7af94c8ae","relate_stocks":{"VTVT":"vTv Therapeutics 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