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Merck shares jumped 5.3% in premarket trading

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{"i18n":{"language":"zh_CN"},"detailType":1,"isChannel":false,"data":{"magic":2,"id":603913385,"tweetId":"603913385","gmtCreate":1638350777673,"gmtModify":1638350777967,"author":{"id":3576803907634733,"idStr":"3576803907634733","authorId":3576803907634733,"authorIdStr":"3576803907634733","name":"UnknownTD","avatar":"https://static.tigerbbs.com/3b4de5039e388fd6c03e422c40499ee8","vip":1,"userType":1,"introduction":"","boolIsFan":false,"boolIsHead":false,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[],"fanSize":19,"starInvestorFlag":false},"themes":[],"images":[],"coverImages":[],"extraTitle":"","html":"<html><head></head><body>pls like&nbsp;</body></html>","htmlText":"<html><head></head><body>pls like&nbsp;</body></html>","text":"pls like","highlighted":1,"essential":1,"paper":1,"likeSize":9,"commentSize":4,"repostSize":0,"favoriteSize":0,"link":"https://laohu8.com/post/603913385","repostId":1116877933,"repostType":4,"repost":{"id":"1116877933","weMediaInfo":{"introduction":"Providing stock market headlines, business news, financials and earnings ","home_visible":1,"media_name":"Tiger Newspress","id":"1079075236","head_image":"https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba"},"pubTimestamp":1638350081,"share":"https://www.laohu8.com/m/news/1116877933?lang=&edition=full","pubTime":"2021-12-01 17:14","market":"us","language":"en","title":"Merck shares jumped 5.3% in premarket trading","url":"https://stock-news.laohu8.com/highlight/detail?id=1116877933","media":"Tiger Newspress","summary":"Merck shares jumped 5.3% in premarket trading as FDA advisers recommended its COVID-19 pill in close","content":"Merck shares jumped 5.3% in premarket trading&nbsp;as&nbsp;FDA advisers recommended its COVID-19 pill in close vote.\n<img src=\"https://static.tigerbbs.com/52b0f147fff1ac74d32cd5d5643fe2b3\" tg-width=\"850\" tg-height=\"620\" referrerpolicy=\"no-referrer\">\nThe Food and Drug Administration advisory committee said Tuesday the benefits of Merck &amp; Co.'s experimental antiviral COVID-19 pill outweigh its risks in a 13-10 vote, with several advisors saying they had concerns about use of the drug in pregnant women.\nThe company is developing the pill, which is called molnupiravir, with privately held Ridgeback Biotherapeutics.\nThe FDA is now expected to deliver its final decision, likely before the end of the year. The regulator often takes into account the recommendation of its advisory committees but is not required to do so.\nIf molnupiravir is authorized by the FDA in the coming weeks, as expected, the treatment will be the first oral COVID-19 pill that patients can take at home.\nMembers of the Antimicrobial Drugs Advisory Committee also suggested a safety-monitoring program, expressed concerns about prescribing the drug to those who are immunocompromised, and shared their concerns about the overall efficacy of the pill.\n\"With the continued spread of the virus and the emergence of variants, additional treatments for COVID-19 are urgently needed. That is why we are moving with speed and rigor to pursue authorizations and to accelerate broad global access to this investigational medicine,\" Dean Li, executive vice president and president of Merck Research Laboratories, said in a statement. \"We are grateful to the members of the advisory committee who reviewed our application, as well as to the patients and investigators who participated in our clinical trials, and we will continue to work with the FDA as the agency completes its review.\"\nSome Wall Street analysts had predicted that the advisers would vote in support of authorization, but with a cautious approach.\n\"Despite these reservations, molnupiravir is also likely to be approved, and demand is likely to exceed their 20 [million] course supply in 2022,\" SVB Leerink analysts wrote on Friday.\nOf the COVID-19 treatments that are currently available, most are used to care for very sick, hospitalized people. This includes the steroid dexamethasone and Gilead Sciences Inc.'s&nbsp;Veklury.\nThe monoclonal antibodies developed by Eli Lilly &amp; Co., Regeneron Pharmaceuticals&nbsp;Inc. (REGN), and Vir Biotechnology Inc.&nbsp;and GlaxoSmithKline&nbsp;can be used to treat people with mild or moderate cases of COVID-19, but these treatments have to be administered by an infusion in a clinical setting.\nMolnupiravir was once held as a game changer in the course of the pandemic, but its importance has shifted as new data from the clinical trial came out and a competitor stepped up.\nWall Street's interest in Merck's pill began to wane in November when Pfizer Inc. <a href=\"https://laohu8.com/S/PFE\">$(PFE)$</a> produced even more compelling results for its COVID-19 drug candidate, demonstrating that Paxlovid reduced the risk of hospitalization and death by a stunning 89% in a clinical trial. The company filed for emergency authorization later in the month.\nThen, last week, Merck shared that its pill reduced the risk of hospitalization and death by 30% in a clinical trial--and not 50% as reported in the interim results. Wall Street is now factoring in growing worries about the omicron variant and the continuing need for new and better treatments for COVID-19.\n\"Concerns over the new omicron variant are increasing expectations on the potential of Pfizer's COVID-19 vaccine Comirnaty and updated data from Merck's oral anti-viral molnupiravir are increasing expectations for Pfizer's anti-viral Paxlovid,\" Mizuho Securities analysts told investors on Monday.\nAnalysts were once over the moon about the sales potential of the first oral COVID-19 pill that works, predicting between $5 billion and $7 billion in sales next year alone. But the arrival of new efficacy data dragged down interest in both the drug and Merck's stock.\nCiti on Monday downgraded Merck's stock to neutral, from buy, citing concerns about the company's experimental HIV drug islatravir and about molnupiravir.\nMerck is seeking authorization for molnupiravir in adults who have tested positive for the virus, are experiencing mild or moderate symptoms, and are at high risk for severe disease. Patients are expected to start treatment within five days of symptoms.\nThe Phase 2/3, randomized, placebo-controlled, double-blind study only enrolled people who were unvaccinated; however, it's unclear whether the pill could be used to treat vaccinated individuals with breakthrough infections if it is authorized.\nMolnupiravir has already been authorized for use in the U.K.","collect":0,"html":"<!DOCTYPE html>\n<html>\n<head>\n<meta http-equiv=\"Content-Type\" content=\"text/html; charset=utf-8\" />\n<meta name=\"viewport\" content=\"width=device-width,initial-scale=1.0,minimum-scale=1.0,maximum-scale=1.0,user-scalable=no\"/>\n<meta name=\"format-detection\" content=\"telephone=no,email=no,address=no\" />\n<title>Merck shares jumped 5.3% in premarket trading</title>\n<style type=\"text/css\">\na,abbr,acronym,address,applet,article,aside,audio,b,big,blockquote,body,canvas,caption,center,cite,code,dd,del,details,dfn,div,dl,dt,\nem,embed,fieldset,figcaption,figure,footer,form,h1,h2,h3,h4,h5,h6,header,hgroup,html,i,iframe,img,ins,kbd,label,legend,li,mark,menu,nav,\nobject,ol,output,p,pre,q,ruby,s,samp,section,small,span,strike,strong,sub,summary,sup,table,tbody,td,tfoot,th,thead,time,tr,tt,u,ul,var,video{ font:inherit;margin:0;padding:0;vertical-align:baseline;border:0 }\nbody{ font-size:16px; line-height:1.5; color:#999; background:transparent; }\n.wrapper{ overflow:hidden;word-break:break-all;padding:10px; }\nh1,h2{ font-weight:normal; line-height:1.35; margin-bottom:.6em; }\nh3,h4,h5,h6{ line-height:1.35; margin-bottom:1em; }\nh1{ font-size:24px; }\nh2{ font-size:20px; }\nh3{ font-size:18px; }\nh4{ font-size:16px; }\nh5{ font-size:14px; }\nh6{ font-size:12px; }\np,ul,ol,blockquote,dl,table{ margin:1.2em 0; }\nul,ol{ margin-left:2em; }\nul{ list-style:disc; }\nol{ list-style:decimal; }\nli,li p{ margin:10px 0;}\nimg{ max-width:100%;display:block;margin:0 auto 1em; }\nblockquote{ color:#B5B2B1; border-left:3px solid #aaa; padding:1em; }\nstrong,b{font-weight:bold;}\nem,i{font-style:italic;}\ntable{ width:100%;border-collapse:collapse;border-spacing:1px;margin:1em 0;font-size:.9em; }\nth,td{ padding:5px;text-align:left;border:1px solid #aaa; }\nth{ font-weight:bold;background:#5d5d5d; }\n.symbol-link{font-weight:bold;}\n/* header{ border-bottom:1px solid #494756; } */\n.title{ margin:0 0 8px;line-height:1.3;color:#ddd; }\n.meta {color:#5e5c6d;font-size:13px;margin:0 0 .5em; }\na{text-decoration:none; color:#2a4b87;}\n.meta .head { display: inline-block; overflow: hidden}\n.head .h-thumb { width: 30px; height: 30px; margin: 0; padding: 0; border-radius: 50%; float: left;}\n.head .h-content { margin: 0; padding: 0 0 0 9px; float: left;}\n.head .h-name {font-size: 13px; color: #eee; margin: 0;}\n.head .h-time {font-size: 11px; color: #7E829C; margin: 0;line-height: 11px;}\n.small {font-size: 12.5px; display: inline-block; transform: scale(0.9); -webkit-transform: scale(0.9); transform-origin: left; -webkit-transform-origin: left;}\n.smaller {font-size: 12.5px; display: inline-block; transform: scale(0.8); -webkit-transform: scale(0.8); transform-origin: left; -webkit-transform-origin: left;}\n.bt-text {font-size: 12px;margin: 1.5em 0 0 0}\n.bt-text p {margin: 0}\n</style>\n</head>\n<body>\n<div class=\"wrapper\">\n<header>\n<h2 class=\"title\">\nMerck shares jumped 5.3% in premarket trading\n</h2>\n\n<h4 class=\"meta\">\n\n\n<a class=\"head\" href=\"https://laohu8.com/wemedia/1079075236\">\n\n\n<div class=\"h-thumb\" style=\"background-image:url(https://static.tigerbbs.com/8274c5b9d4c2852bfb1c4d6ce16c68ba);background-size:cover;\"></div>\n\n<div class=\"h-content\">\nTiger Newspress \n2021-12-01 17:14\n</div>\n\n</a>\n\n\n</h4>\n\n</header>\n<article>\nMerck shares jumped 5.3% in premarket trading&nbsp;as&nbsp;FDA advisers recommended its COVID-19 pill in close vote.\n<img src=\"https://static.tigerbbs.com/52b0f147fff1ac74d32cd5d5643fe2b3\" tg-width=\"850\" tg-height=\"620\" referrerpolicy=\"no-referrer\">\nThe Food and Drug Administration advisory committee said Tuesday the benefits of Merck &amp; Co.'s experimental antiviral COVID-19 pill outweigh its risks in a 13-10 vote, with several advisors saying they had concerns about use of the drug in pregnant women.\nThe company is developing the pill, which is called molnupiravir, with privately held Ridgeback Biotherapeutics.\nThe FDA is now expected to deliver its final decision, likely before the end of the year. The regulator often takes into account the recommendation of its advisory committees but is not required to do so.\nIf molnupiravir is authorized by the FDA in the coming weeks, as expected, the treatment will be the first oral COVID-19 pill that patients can take at home.\nMembers of the Antimicrobial Drugs Advisory Committee also suggested a safety-monitoring program, expressed concerns about prescribing the drug to those who are immunocompromised, and shared their concerns about the overall efficacy of the pill.\n\"With the continued spread of the virus and the emergence of variants, additional treatments for COVID-19 are urgently needed. That is why we are moving with speed and rigor to pursue authorizations and to accelerate broad global access to this investigational medicine,\" Dean Li, executive vice president and president of Merck Research Laboratories, said in a statement. \"We are grateful to the members of the advisory committee who reviewed our application, as well as to the patients and investigators who participated in our clinical trials, and we will continue to work with the FDA as the agency completes its review.\"\nSome Wall Street analysts had predicted that the advisers would vote in support of authorization, but with a cautious approach.\n\"Despite these reservations, molnupiravir is also likely to be approved, and demand is likely to exceed their 20 [million] course supply in 2022,\" SVB Leerink analysts wrote on Friday.\nOf the COVID-19 treatments that are currently available, most are used to care for very sick, hospitalized people. This includes the steroid dexamethasone and Gilead Sciences Inc.'s&nbsp;Veklury.\nThe monoclonal antibodies developed by Eli Lilly &amp; Co., Regeneron Pharmaceuticals&nbsp;Inc. (REGN), and Vir Biotechnology Inc.&nbsp;and GlaxoSmithKline&nbsp;can be used to treat people with mild or moderate cases of COVID-19, but these treatments have to be administered by an infusion in a clinical setting.\nMolnupiravir was once held as a game changer in the course of the pandemic, but its importance has shifted as new data from the clinical trial came out and a competitor stepped up.\nWall Street's interest in Merck's pill began to wane in November when Pfizer Inc. <a href=\"https://laohu8.com/S/PFE\">$(PFE)$</a> produced even more compelling results for its COVID-19 drug candidate, demonstrating that Paxlovid reduced the risk of hospitalization and death by a stunning 89% in a clinical trial. The company filed for emergency authorization later in the month.\nThen, last week, Merck shared that its pill reduced the risk of hospitalization and death by 30% in a clinical trial--and not 50% as reported in the interim results. Wall Street is now factoring in growing worries about the omicron variant and the continuing need for new and better treatments for COVID-19.\n\"Concerns over the new omicron variant are increasing expectations on the potential of Pfizer's COVID-19 vaccine Comirnaty and updated data from Merck's oral anti-viral molnupiravir are increasing expectations for Pfizer's anti-viral Paxlovid,\" Mizuho Securities analysts told investors on Monday.\nAnalysts were once over the moon about the sales potential of the first oral COVID-19 pill that works, predicting between $5 billion and $7 billion in sales next year alone. But the arrival of new efficacy data dragged down interest in both the drug and Merck's stock.\nCiti on Monday downgraded Merck's stock to neutral, from buy, citing concerns about the company's experimental HIV drug islatravir and about molnupiravir.\nMerck is seeking authorization for molnupiravir in adults who have tested positive for the virus, are experiencing mild or moderate symptoms, and are at high risk for severe disease. Patients are expected to start treatment within five days of symptoms.\nThe Phase 2/3, randomized, placebo-controlled, double-blind study only enrolled people who were unvaccinated; however, it's unclear whether the pill could be used to treat vaccinated individuals with breakthrough infections if it is authorized.\nMolnupiravir has already been authorized for use in the U.K.\n\n</article>\n</div>\n</body>\n</html>\n","type":0,"thumbnail":"","relate_stocks":{"MRK":"默沙东"},"is_english":true,"share_image_url":"https://static.laohu8.com/e9f99090a1c2ed51c021029395664489","article_id":"1116877933","content_text":"Merck shares jumped 5.3% in premarket trading as FDA advisers recommended its COVID-19 pill in close vote.\n\nThe Food and Drug Administration advisory committee said Tuesday the benefits of Merck & Co.'s experimental antiviral COVID-19 pill outweigh its risks in a 13-10 vote, with several advisors saying they had concerns about use of the drug in pregnant women.\nThe company is developing the pill, which is called molnupiravir, with privately held Ridgeback Biotherapeutics.\nThe FDA is now expected to deliver its final decision, likely before the end of the year. The regulator often takes into account the recommendation of its advisory committees but is not required to do so.\nIf molnupiravir is authorized by the FDA in the coming weeks, as expected, the treatment will be the first oral COVID-19 pill that patients can take at home.\nMembers of the Antimicrobial Drugs Advisory Committee also suggested a safety-monitoring program, expressed concerns about prescribing the drug to those who are immunocompromised, and shared their concerns about the overall efficacy of the pill.\n\"With the continued spread of the virus and the emergence of variants, additional treatments for COVID-19 are urgently needed. That is why we are moving with speed and rigor to pursue authorizations and to accelerate broad global access to this investigational medicine,\" Dean Li, executive vice president and president of Merck Research Laboratories, said in a statement. \"We are grateful to the members of the advisory committee who reviewed our application, as well as to the patients and investigators who participated in our clinical trials, and we will continue to work with the FDA as the agency completes its review.\"\nSome Wall Street analysts had predicted that the advisers would vote in support of authorization, but with a cautious approach.\n\"Despite these reservations, molnupiravir is also likely to be approved, and demand is likely to exceed their 20 [million] course supply in 2022,\" SVB Leerink analysts wrote on Friday.\nOf the COVID-19 treatments that are currently available, most are used to care for very sick, hospitalized people. This includes the steroid dexamethasone and Gilead Sciences Inc.'s Veklury.\nThe monoclonal antibodies developed by Eli Lilly & Co., Regeneron Pharmaceuticals Inc. (REGN), and Vir Biotechnology Inc. and GlaxoSmithKline can be used to treat people with mild or moderate cases of COVID-19, but these treatments have to be administered by an infusion in a clinical setting.\nMolnupiravir was once held as a game changer in the course of the pandemic, but its importance has shifted as new data from the clinical trial came out and a competitor stepped up.\nWall Street's interest in Merck's pill began to wane in November when Pfizer Inc. $(PFE)$ produced even more compelling results for its COVID-19 drug candidate, demonstrating that Paxlovid reduced the risk of hospitalization and death by a stunning 89% in a clinical trial. The company filed for emergency authorization later in the month.\nThen, last week, Merck shared that its pill reduced the risk of hospitalization and death by 30% in a clinical trial--and not 50% as reported in the interim results. Wall Street is now factoring in growing worries about the omicron variant and the continuing need for new and better treatments for COVID-19.\n\"Concerns over the new omicron variant are increasing expectations on the potential of Pfizer's COVID-19 vaccine Comirnaty and updated data from Merck's oral anti-viral molnupiravir are increasing expectations for Pfizer's anti-viral Paxlovid,\" Mizuho Securities analysts told investors on Monday.\nAnalysts were once over the moon about the sales potential of the first oral COVID-19 pill that works, predicting between $5 billion and $7 billion in sales next year alone. But the arrival of new efficacy data dragged down interest in both the drug and Merck's stock.\nCiti on Monday downgraded Merck's stock to neutral, from buy, citing concerns about the company's experimental HIV drug islatravir and about molnupiravir.\nMerck is seeking authorization for molnupiravir in adults who have tested positive for the virus, are experiencing mild or moderate symptoms, and are at high risk for severe disease. Patients are expected to start treatment within five days of symptoms.\nThe Phase 2/3, randomized, placebo-controlled, double-blind study only enrolled people who were unvaccinated; however, it's unclear whether the pill could be used to treat vaccinated individuals with breakthrough infections if it is authorized.\nMolnupiravir has already been authorized for use in the U.K.","news_type":1},"isVote":1,"tweetType":1,"viewCount":288,"commentLimit":10,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"symbols":[],"verified":2,"subType":0,"readableState":1,"langContent":"CN","currentLanguage":"CN","warmUpFlag":false,"orderFlag":false,"shareable":true,"causeOfNotShareable":"","featuresForAnalytics":[],"commentAndTweetFlag":false,"andRepostAutoSelectedFlag":false,"upFlag":false,"length":7,"xxTargetLangEnum":"ZH_CN"},"commentList":[],"isCommentEnd":true,"isTiger":false,"isWeiXinMini":false,"url":"/m/post/603913385"}