石药集团(01093)：SYH2062注射液获临床试验批准

智通财经12-23 17:29

智通财经APP讯，石药集团(01093)发布公告，集团自主研发的化学1类新药SYH2062注射液(双链小干扰RNA(si RNA)药物)(该产品)已获得中华人民共和国国家药品监督管理局批准，可以在中国开展临床试验。

该产品是一款通过偶联乙酰半乳糖胺(Gal NAc)递送的si RNA药物，可以靶向抑制血管紧张素原(AGT)，适用于治疗高血压。该产品通过优化序列和化学修饰的策略，实现更持久的基因沉默效果，有望成为每6个月给药一次的稳定控压药物。临床前研究显示，该产品的药物活性作用时间明显长于同类型si RNA产品，预期具有药物作用效果持久、安全性良好及患者依从性高等差异化优势，有较大临床开发价值。

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