加科思-B(01167)在2024年第66届美国血液学会年会上展示了BET抑制剂JAB-8263 治疗骨髓纤维化(MF)临床一期的初步数据

智通财经12-09

智通财经APP讯，加科思-B(01167)发布公告，公司在加利福尼亚州圣地牙哥举行的2024年第66届美国血液学会(ASH)年会上展示了BET抑制剂JAB-8263 治疗骨髓纤维化(MF)临床一期的初步数据。

资料显示，JAB-8263具有良好的耐受性，二期推荐剂量为0.3毫克(每日给药)。 JAB-8263单药治疗骨髓纤维化适应症的初步疗效资料是令人鼓舞的。大多数患者出现脾脏缩小(spleen volume reduction, SVR)以及总症状评分(total symptom score，TSS)的降低。

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