阿尔茨海默病疗法再获批准，诺华加码肾病领域，诺和诺德单抗疗法在中国启动急性心梗3期临床

医药经济报08-23 20:44

1. 阿尔茨海默病疗法再获批准卫材（Eisai）和渤健（Biogen）今天宣布，其联合开发的阿尔茨海默病疗法Leqembi（lecanemab）已获得英国药品和健康产品管理局（MHRA）的上市许可，用以治疗由阿尔茨海默病（AD）引起的轻度认知障碍（MCI）和轻度痴呆成人患者，这些患者携带一个APOE E4等位基因或不携带APOE E4等位基因。根据新闻稿，英国成为欧洲首个批准Leqembi的国家，...

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AD临床3期随机试验的数据。Leqembi治疗达到了主要终点（18个月时整体认知和功能量表、临床痴呆评级-框架总和[CDR-SB]与基线相比的变化）和所有关键次要终点，并且结果具有统计学意义。2.诺华加码肾病领域！与知名投资机构成立xRNA疗法公司8月22日，诺华宣布已与知名投资机构Versant Ventures联合成立专注于开发xRNA疗法的生物技术公司Borealis Biosciences，并且两方将共同提供1.5亿美元用于新公司的A轮融资。此外，诺华还承诺将向Borealis Biosciences提供高达1亿美元的战略研究合作资金。Borealis Biosciences将利用诺华的xRNA技术平台开发靶向人体天然mRNA的疗法，以调节治病蛋白质的产生，进而达到疾病治疗目的。作为合作协议的一部分，诺华将有权从Borealis Biosciences手中收购两个未来可开发的项目，以扩大其在肾病领域的布局。作为回报，Borealis 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