加科思(01167)：完成JAB-3312与Glecirasib联用三期临床首例患者给药

金吾财讯08-07

金吾财讯 | 加科思(01167)公布，公司自主研发的SHP2抑制剂JAB-3312与KRASG12C抑制剂Glecirasib联合用药用于KRASG12C突变的一线非小细胞肺癌(NSCLC)对照标准疗法(PD-1抗体和化疗联合治疗)的注册性三期临床试验已完成首例患者给药。JAB-3312是全球首个进入注册性临床试验的SHP2抑制剂。据悉，Glecirasib单药用于KRASG12C突变二线非小细胞肺癌的新药上市申请(NDA)已于2024年5月21日已被中国国家药品监督管理局(NMPA)药品审评中心(CDE)获批优先审评。

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