J&J Says Covid-19 Vaccine Booster Two Months After First Shot Increases Protection

The Wall Street Journal2021-09-21

Trial participants in the U.S. who received a second dose eight weeks after the first had 94% protection against the illness. Johnson & JohnsonJNJ-0.57%said a booster dose of its Covid-19 vaccine ...

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精彩评论

Min_max
2021-09-22
Min_max
booster shots are important
lihodinho
2021-09-21
lihodinho
Yea
- lihodinho:
  yea
2020TS
2021-09-21
2020TS
Any side effect info?
iamme
2021-09-21
iamme
Ok
- RChia:
  Ok
- lavin:
  Okie
YeeMeng
2021-09-21
YeeMeng
Great news for Pfizer?
- JohnLeeToday:
  MaybE
- iamme:
  ya
- bostonxsgp:
  ok

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Participants in the U.S. had 94% protection against the illness. J&J didn’t explain the reason for the difference in efficacy rates.\nA double dose of the vaccine provided participants with 100% protection against severe or critical Covid-19 at least two weeks after the second shot, J&J said.\nThe company earlier this year said a large clinical trial showed thata single dose of its vaccine was 66% effectiveat protecting people from moderate to severe Covid-19.\n“We now have generated evidence that a booster shot further increases protection against Covid-19 and is expected to extend the duration of protection significantly,” said Paul Stoffels, chief scientific officer at J&J. The company said it has shared available data with the Food and Drug Administration.\nThe late-stage study tested a two-dose regimen of the vaccine in about 32,000 people aged 18 and over in the U.S., Belgium, Brazil, Colombia, France, Germany, the Philippines, South Africa, Spain and the U.K., J&J said. The company said about half of participants received the placebo but didn’t say how many participants were in the U.S.\nJ&J said Tuesday that an extra shot given two months after the firstboosted antibody levels four to six times higherthan observed after the single shot. It said a booster administered six months after the first shot initially increased antibody levels ninefold and continued to climb to 12-fold higher four weeks after the second shot. J&J released some of thesix-month boosting datain August.\nNeither that data nor the results released Tuesday have been peer reviewed or published in a scientific journal.\n“The data are supportive of giving a second shot of the J&J vaccine, anywhere from two months onwards,” said Dan Barouch, an immunologist at Beth Israel Deaconess Medical Center in Boston who helped develop J&J’s vaccine. “The longer you wait, the better the boost will likely be.”\nHe said some countries might choose to offer boosters, while others might stick with a single shot. “Different people or different countries might actually make different choices based on what their desires or needs are,” Dr. Barouch said.\nJ&J also highlighted data it said showed its single-shot vaccine offered durable protectioneven as the Delta variant spreads.\nIn a study of about 390,000 people in the U.S. who received the J&J vaccine compared with 1.52 million similar unvaccinated people from March to late July 2021,the single-dose vaccine was 79% effectiveagainst infections and 81% effective against hospitalizations related to Covid-19.\nThe Biden administration is hoping to begin at least part of its boosting strategy this week. 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A Centers for Disease Control and Prevention advisory panel is set to discuss the Pfizer boosting strategy on Wednesday and Thursday.\nPlans to offer boosters more widely were scaled back as federal health officials and medical expertsremain divided over the need for boostersand regulators have asked for more time to review data from J&J andModernaInc.","kind":null,"is_publish_news":true,"is_publish_highlight":true,"is_publish_live":false,"is_publish_wemedia":null,"editions":null,"column":"","sentiment":"0","news_tag":"","news_rank":0,"symbols":[],"gpt_button":1},"commentList":[{"id":869330449,"gmtCreate":1632242193281,"gmtModify":1632801804985,"author":{"id":"3585869414507662","authorId":"3585869414507662","name":"Min_max","avatar":"https://static.tigerbbs.com/a19718c12eabe8d2a0c3e3a797bd178f","vip":1,"crmLevel":3,"crmLevelSwitch":0,"idStr":"3585869414507662","authorIdStr":"3585869414507662"},"htmlText":"booster shots are important&nbsp;","listText":"booster shots are 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side effect info?","listText":"Any side effect info?","text":"Any side effect 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news for Pfizer?","listText":"Great news for Pfizer?","text":"Great news for Pfizer?","images":[],"top":1,"highlighted":1,"essential":1,"paper":1,"likeSize":6,"commentSize":3,"repostSize":0,"link":"https://laohu8.com/post/869008484","repostId":1157787805,"repostType":4,"isVote":1,"likeStatus":false,"favoriteStatus":false,"reportStatus":false,"tweetType":1,"comments":[{"id":5945702,"gmtCreate":1632223418341,"gmtModify":1634790275342,"authorId":3584930099421547,"author":{"id":3584930099421547,"idStr":"3584930099421547","authorId":3584930099421547,"name":"JohnLeeToday","avatar":"https://static.tigerbbs.com/f50ae8cdbdb7309ac4d36b63ed8e0734","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":869008484,"type":1,"supId":0,"prevId":0,"content":"MaybE","text":"MaybE","html":"MaybE"},{"id":5945703,"gmtCreate":1632223431001,"gmtModify":1634790275232,"authorId":3581890649918848,"author":{"id":3581890649918848,"idStr":"3581890649918848","authorId":3581890649918848,"name":"iamme","avatar":"https://static.tigerbbs.com/fe38c555d52f708161a2da155b67f28b","vip":1,"crmLevel":4,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":869008484,"type":1,"supId":0,"prevId":0,"content":"<u>ya</u>","text":"<u>ya</u>","html":"<u>ya</u>"},{"id":5945754,"gmtCreate":1632223909042,"gmtModify":1634790271733,"authorId":3584157491931754,"author":{"id":3584157491931754,"idStr":"3584157491931754","authorId":3584157491931754,"name":"bostonxsgp","avatar":"https://static.tigerbbs.com/55d82efabeabddb18cc2d6ca7a71a36f","vip":1,"crmLevel":2,"crmLevelSwitch":0,"individualDisplayBadges":[]},"repliedAuthorId":0,"objectId":869008484,"type":1,"supId":0,"prevId":0,"content":"ok","text":"ok","html":"ok"}],"langContent":"EN"}],"isCommentEnd":false,"newsSizeData":{"likeSize":38,"commentSize":5,"repostSize":0,"favoriteSize":0,"likeStatus":false,"favoriteStatus":false},"APP":{"userAgent":"Mozilla/5.0 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