Ionis Pharmaceuticals, Inc(IONS)_个股概要_股票价格_最新资讯_行情走势_历史数据 - 老虎社区

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IONS Ionis Pharmaceuticals, Inc

盘前交易 11-12 08:05:46 EST

28.33

+0.14

+0.50%

盘前28.34

+0.01+0.04%

08:00 EST

最高29.42	最低28.25	成交量655.20万
今开28.60	昨收28.19	日振幅4.15%
总市值47.08亿	流通市值45.87亿	总股本1.66亿
成交额1.87亿	换手率4.05%	流通股本1.62亿
市净率--	ROE--	每股收益0.00
52周最高--	52周最低--	市盈率--
股息--	股息收益率--	ROA--

数据加载中...

北京优虎网络科技有限公司

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Pharmaceuticals盘中下跌8.39%，券商密集下调目标价叠加Tryngolza预期走弱","url":"https://stock-news.laohu8.com/highlight/detail?id=1102835402","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1102835402?lang=zh_cn&edition=full","pubTime":"2026-11-11 00:12","pubTimestamp":1794327157,"startTime":"0","endTime":"0","summary":"11月11日，Ionis Pharmaceuticals盘中下跌8.39%，报28.4美元/股，成交额5316.35万美元。更核心的压力来自Tryngolza销售预期下修。公司此前将该药全年销售预测从1亿至1.1亿美元下调至5000万美元，尽管第三季度营收2.43亿美元、同比增长55%，且亏损好于预期，但全年营收指引维持在8.75亿至9亿美元，仍低于市场预期，财报后的负面情绪持续发酵。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis遭多家机构下调目标价，Tryngolza预期走弱","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1182472724","title":"异动解读｜Ionis Pharmaceuticals盘中下跌20.27%，财报后维持全年指引低于市场预期","url":"https://stock-news.laohu8.com/highlight/detail?id=1182472724","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1182472724?lang=zh_cn&edition=full","pubTime":"2026-11-09 22:31","pubTimestamp":1794234690,"startTime":"0","endTime":"0","summary":"11月9日，Ionis Pharmaceuticals盘中下跌20.27%，报31.615美元/股，成交额2434.82万美元。消息面上，公司公布第三季度营收2.43亿美元，高于上年同期的1.57亿美元，也超过市场预期；每股亏损0.66美元，好于预期亏损1.23美元。不过，公司维持全年营收指引在8.75亿至9亿美元，低于市场预期的9.222亿美元，成为股价承压的直接背景。公司是一家聚焦RNA靶向疗法的商业阶段生物技术企业，已拥有七种上市药物，并在神经病学、心脏代谢疾病等领域推进管线开发。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。）","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"财报后指引不及预期，Ionis股价承压","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1187364000","title":"异动解读｜Ionis Pharmaceuticals盘前下跌6.04%，缺乏明确新催化下回吐近期评级利好","url":"https://stock-news.laohu8.com/highlight/detail?id=1187364000","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1187364000?lang=zh_cn&edition=full","pubTime":"2026-11-09 19:41","pubTimestamp":1794224481,"startTime":"0","endTime":"0","summary":"11月9日，Ionis Pharmaceuticals盘前下跌6.04%，报37.0403美元/股，成交额14.37万美元。不过，上述利好均非当日新增信息，且股价现水平已明显低于机构彼时给出的目标价区间，当前这笔盘前回落暂未见到新的明确公告可直接解释。伊奥尼斯制药公司深耕RNA靶向药物领域，已拥有七种上市药物，并围绕神经病学、心脏代谢疾病等方向推进商业化与管线开发。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1115436636","title":"异动解读｜Ionis Pharmaceuticals盘中上涨5.31%，sefaxersen三期试验达成主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1115436636","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1115436636?lang=zh_cn&edition=full","pubTime":"2026-10-10 00:25","pubTimestamp":1791563126,"startTime":"0","endTime":"0","summary":"10月10日，Ionis Pharmaceuticals盘中上涨5.31%，报45.6美元/股，成交额7606.42万美元。消息面上，公司与罗氏联合开发的试验性药物sefaxersen在三期IMAgINATION临床试验中达到主要终点，用于治疗成人原发性IgA肾病，第37周数据显示该药物相较安慰剂实现具有统计学与临床意义的蛋白尿降低，且安全性与此前研究一致。该事件进一步强化了公司在RNA靶向药物管线上的推进预期，此前一周其另一款ALS药物ulefnersen三期试验亦达到主要终点。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。）","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis盘中上涨，肾病新药三期达标","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1123663815","title":"异动解读｜Ionis Pharmaceuticals夜盘上涨5.89%，sefaxersen三期试验达到主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1123663815","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1123663815?lang=zh_cn&edition=full","pubTime":"2026-10-07 08:03","pubTimestamp":1791331405,"startTime":"0","endTime":"0","summary":"10月7日，Ionis Pharmaceuticals夜盘上涨5.89%，报46.59美元/股，成交额2.89万美元。消息面上，公司与罗氏联合开发的试验性药物sefaxersen在三期IMAgINATION临床试验中达到主要终点，用于治疗成人原发性IgA肾病。第37周数据显示，sefaxersen相较安慰剂实现了具有统计学与临床意义的蛋白尿降低，且安全性与此前研究一致。该研究将继续评估两年内肾功能变化，以第105周估计肾小球滤过率为指标。此前一周，Ionis的另一款ALS药物ulefnersen三期试验同样达到主要终点，显示公司在多个管线上的持续推进。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis夜盘上涨，肾病新药三期达主要终点","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1161973403","title":"异动解读｜Ionis Pharmaceuticals盘中上涨5.15%，连续两项三期试验取得积极结果提振市场信心","url":"https://stock-news.laohu8.com/highlight/detail?id=1161973403","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1161973403?lang=zh_cn&edition=full","pubTime":"2026-09-29 02:37","pubTimestamp":1790620649,"startTime":"0","endTime":"0","summary":"9月29日，Ionis Pharmaceuticals盘中上涨5.15%，报46.79美元/股，成交额8349.88万美元。两项试验连续成功，叠加此前zilganersen获FDA批准治疗亚历山大病，有效修复了7月心脏病药物eplontersen三期试验失败以来的市场信心。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis连获两项三期成功，股价上涨提振信心","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1110509386","title":"异动解读｜Ionis Pharmaceuticals盘中下跌5.05%，多项管线利好未能扭转心血管管线失利后持续抛压","url":"https://stock-news.laohu8.com/highlight/detail?id=1110509386","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1110509386?lang=zh_cn&edition=full","pubTime":"2026-09-23 22:57","pubTimestamp":1790175464,"startTime":"0","endTime":"0","summary":"9月23日，Ionis Pharmaceuticals盘中下跌5.05%，报43.44美元/股，成交额3311.68万美元。尽管当日公司迎来密集管线利好，股价仍大幅回落。然而，市场对此反应冷淡，盘前涨幅迅速回吐并转为下跌。背景上，公司此前与阿斯利康合作的eplontersen在ATTR心肌病三期试验中未达主要终点，叠加美国银行、TD Cowen等机构接连下调目标价，心血管核心管线的接连失利已严重削弱市场信心，股价自52周高点86.74美元已累计腰斩过半，利好消息短期内难以扭转悲观预期。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis盘中下跌，多项利好难挽抛压","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2669488169","title":"Ionis Pharmaceuticals（IONS）涨超2% 三期试验取得积极结果","url":"https://stock-news.laohu8.com/highlight/detail?id=2669488169","media":"金吾财讯","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/2669488169?lang=zh_cn&edition=full","pubTime":"2026-09-23 19:15","pubTimestamp":1790162157,"startTime":"0","endTime":"0","summary":"金吾财讯 | Ionis Pharmaceuticals（IONS）美股盘前股价上扬，最新涨2.25%，报46.78美元。消息面上，Ionis Pharmaceuticals的sefaxersen在三期IMAgINATION临床试验达到原发性IgA肾病（IgAN）成人患者主要终点。试验第37周数据显示，sefaxersen可显著降低患者24小时尿蛋白肌酐比值（UPCR），蛋白尿降幅具备统计学与临床意义，该指标是肾损伤核心标志物。这款皮下注射药物的安全性、耐受性与此前研究数据保持一致，未出现新增安全风险。","market":"fut","thumbnail":"https://static.szfiu.com/news/20250107/MDYxNTA2ZjhkOWVmNGY4NWFiMzk3MGE5NjBhODhjODE3MzYyMzc3Njg0MzY=.png","type":0,"news_type":0,"thumbnails":["https://static.szfiu.com/news/20250107/MDYxNTA2ZjhkOWVmNGY4NWFiMzk3MGE5NjBhODhjODE3MzYyMzc3Njg0MzY=.png"],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"306389","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1184074764","title":"异动解读｜Ionis Pharmaceuticals盘前上涨5.9%，多款在研药物三期试验接连达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1184074764","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1184074764?lang=zh_cn&edition=full","pubTime":"2026-09-23 16:01","pubTimestamp":1790150471,"startTime":"0","endTime":"0","summary":"9月23日，Ionis Pharmaceuticals盘前上涨5.9%，报47.6美元/股，成交额7.51万美元。消息面上，公司近日迎来多重管线利好共振。其与大冢制药合作的Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的三期Fusion研究中达到主要终点，显著改善患者生存与功能，关键次要终点亦获达成，双方计划与FDA讨论加速审批路径。此外，公司此前已获FDA批准Zilganersen用于治疗亚历山大病，商业化进程持续推进。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis多管线告捷，盘前迎来上涨","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1116292294","title":"异动解读｜Ionis Pharmaceuticals夜盘上涨5.9%，Ulefnersen三期Fusion研究达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1116292294","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1116292294?lang=zh_cn&edition=full","pubTime":"2026-09-23 14:33","pubTimestamp":1790145188,"startTime":"0","endTime":"0","summary":"9月22日，Ionis Pharmaceuticals夜盘上涨5.9%，报48.45美元/股，成交额25.97万美元。消息面上，公司宣布其试验性药物Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的三期Fusion研究中取得积极顶线结果，主要终点实现具有统计学意义的显著改善。Ulefnersen是一种反义寡核苷酸药物，旨在从根源干预疾病进程，若最终获批将成为FUS-ALS领域首个潜在的疾病修饰疗法，填补该适应症治疗空白。此外，公司另一在研药物Zilganersen的FDA目标审评日期亦定于9月22日，多重催化剂共振推动股价走强。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis夜盘大涨，ALS新药三期达主要终点","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1172335676","title":"异动解读｜Ionis Pharmaceuticals盘前上涨7.15%，Ulefnersen三期Fusion研究达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1172335676","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1172335676?lang=zh_cn&edition=full","pubTime":"2026-09-22 20:05","pubTimestamp":1790078701,"startTime":"0","endTime":"0","summary":"9月22日，Ionis Pharmaceuticals盘前上涨7.15%，报46.95美元/股，成交额44.1万美元。消息面上，公司宣布其试验性药物Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的三期Fusion研究中取得积极顶线结果，主要终点实现具有统计学意义的显著改善。Ulefnersen是一种反义寡核苷酸药物，旨在从根源干预疾病进程，若最终获批将成为FUS-ALS领域首个潜在的疾病修饰疗法，填补该适应症治疗空白。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Ionis盘前上涨，FUS-ALS新药三期达主要终点","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1191604640","title":"Ionis Pharmaceuticals：Ulefnersen在Fus-ALS关键终点上取得统计学显著改善","url":"https://stock-news.laohu8.com/highlight/detail?id=1191604640","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1191604640?lang=zh_cn&edition=full","pubTime":"2026-09-22 20:01","pubTimestamp":1790078499,"startTime":"0","endTime":"0","summary":"Ionis Pharmaceuticals公司近日宣布，其试验性药物Ulefnersen在治疗FUS基因突变型肌萎缩侧索硬化症的临床研究中，于主要终点上实现了具有统计学意义的显著改善。Ionis Pharmaceuticals凭借其反义寡核苷酸技术平台，致力于开发能够精准靶向疾病根源的创新疗法，Ulefnersen正是这一战略布局下的重要候选药物。公司方面表示，这些令人鼓舞的临床数据将进一步支持Ulefnersen的持续推进，并计划在未来的医学会议上公布详细研究结果，同时与监管机构沟通后续开发路径。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1115354806","title":"Ionis公布Ulefnersen三期Fusion研究积极顶线结果，推进FUS-ALS首个潜在疾病修饰疗法迈出关键一步","url":"https://stock-news.laohu8.com/highlight/detail?id=1115354806","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1115354806?lang=zh_cn&edition=full","pubTime":"2026-09-22 20:01","pubTimestamp":1790078494,"startTime":"0","endTime":"0","summary":"Ionis制药公司今日宣布，其针对Ulefnersen的三期Fusion研究取得了积极的顶线结果。这一里程碑式的进展，标志着该公司在推动FUS-ALS首个潜在疾病修饰疗法方面，踏出了至关重要的一步。该研究旨在评估Ulefnersen在治疗特定基因突变型ALS患者中的疗效与安全性。Ulefnersen作为一种反义寡核苷酸药物，其设计初衷是从根源上干预疾病进程。业内观察人士指出，这项突破若最终获得批准，不仅将填补FUS-ALS领域的治疗空白，更可能重塑整个ALS治疗格局。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1124966303","title":"异动解读｜Ionis Pharmaceuticals盘中下跌5.01%，心血管管线接连失利叠加机构下调目标价持续承压","url":"https://stock-news.laohu8.com/highlight/detail?id=1124966303","media":"行情直击","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1124966303?lang=zh_cn&edition=full","pubTime":"2026-09-19 03:59","pubTimestamp":1789761565,"startTime":"0","endTime":"0","summary":"9月19日，Ionis Pharmaceuticals盘中下跌5.01%，报44.4美元/股，成交额1.46亿美元，股价延续近期跌势。消息面上，公司心血管核心管线近期接连遭遇重挫。两次关键管线的接连失利严重削弱了市场对公司核心研发实力的信心。此外，美国银行将公司目标价从93美元下调至91美元，TD Cowen亦将目标价从108美元下调至94美元，机构预期持续回落加剧了抛压。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis心血管管线接连失利，股价承压下行","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1124058402","title":"异动解读｜Ionis Pharmaceuticals盘中上涨5.03%，报45.78美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1124058402","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1124058402?lang=zh_cn&edition=full","pubTime":"2026-09-17 21:43","pubTimestamp":1789652612,"startTime":"0","endTime":"0","summary":"9月17日，Ionis Pharmaceuticals盘中上涨5.03%，报45.78美元/股，成交额728.41万美元。Ionis Pharmaceuticals所在的生物科技行业中，个股中，Moderna涨5.06%，安进涨0.42%，Hyperliquid Strategies涨7.56%，bioAffinity Technologies涨24.3%，Praxis Precision Medicines涨0.36%。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。）","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1141743387","title":"异动解读｜Ionis Pharmaceuticals盘中下跌5.25%，心血管管线接连失利持续承压","url":"https://stock-news.laohu8.com/highlight/detail?id=1141743387","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1141743387?lang=zh_cn&edition=full","pubTime":"2026-09-17 03:13","pubTimestamp":1789585996,"startTime":"0","endTime":"0","summary":"9月17日，Ionis Pharmaceuticals盘中下跌5.25%，报44.77美元/股，成交额2.02亿美元，股价延续近期跌势。消息面上，公司心血管核心管线接连遭遇重挫。9月8日，公司与诺华联合开发的心脏病药物pelacarsen在晚期临床试验中未达主要终点，当日盘前即暴跌13%。两次关键心血管管线的接连失利严重削弱了市场对公司核心研发实力的信心。此外，美国银行近期将公司目标价从93美元下调至91美元，TD Cowen亦将目标价从108美元下调至94美元，机构预期持续回落加剧了抛压。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis心血管管线接连失利，股价持续承压","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1159701623","title":"异动解读｜Ionis Pharmaceuticals盘中下跌6.29%，心脏病药物试验接连失败持续承压","url":"https://stock-news.laohu8.com/highlight/detail?id=1159701623","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1159701623?lang=zh_cn&edition=full","pubTime":"2026-09-16 00:13","pubTimestamp":1789488811,"startTime":"0","endTime":"0","summary":"9月15日，Ionis Pharmaceuticals盘中下跌6.29%，报48.2美元/股，成交额9541.81万美元，股价延续近期颓势。9月8日，公司与诺华联合开发的心脏病药物pelacarsen在晚期临床试验中未达主要终点，当日盘前即暴跌13%。此前7月，公司与阿斯利康合作的Eplontersen针对淀粉样心肌病的三期试验同样宣告失败，股价曾单日暴跌超20%。两次关键心血管管线的接连失利严重削弱了市场对公司核心研发实力的信心。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"心脏病药物试验接连失败，Ionis股价承压下跌","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1102551583","title":"异动解读｜Ionis 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Pharmaceuticals是一家完全整合的商业阶段生物技术公司，拥有七种已上市药物，管线横跨神经病学、心脏代谢疾病等领域。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis盘中下跌，诺华合作药III期未达终点","news_tag":"corporation,dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1176841836","title":"异动解读｜Ionis Pharmaceuticals盘前下跌12.19%，合作伙伴诺华Lp(a)重磅药III期试验未达主要终点","url":"https://stock-news.laohu8.com/highlight/detail?id=1176841836","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1176841836?lang=zh_cn&edition=full","pubTime":"2026-09-08 18:44","pubTimestamp":1788864278,"startTime":"0","endTime":"0","summary":"9月8日，Ionis Pharmaceuticals盘前下跌12.19%，报50.95美元/股，成交额499.03万美元。消息面上，公司合作伙伴诺华于9月4日宣布，由Ionis发现并早期开发的pelacarsen在III期LpHORIZON心血管结局试验中未达主要终点。Ionis Pharmaceuticals是一家完全整合的商业阶段生物技术公司，拥有七种已上市药物，管线横跨神经病学、心脏代谢疾病等领域。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Ionis再遭III期失利，盘前重挫超12%","news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IONS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1180678017","title":"IONIS制药股价盘前下跌13%，该公司心脏病药物晚期试验失败","url":"https://stock-news.laohu8.com/highlight/detail?id=1180678017","media":"老虎快讯","labels":[],"top":-1,"itemType":null,"share":"https://www.laohunote.com/m/news/1180678017?lang=zh_cn&edition=full","pubTime":"2026-09-08 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