Hoth Therapeutics(HOTH)_个股概要_股票价格_最新资讯_行情走势_历史数据 - 老虎社区

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HOTH Hoth Therapeutics

休市中 04-24 16:00:00 EDT

0.8099

+0.0121

+1.52%

盘后0.8100

+0.0001+0.01%

19:59 EDT

最高0.8100	最低0.7580	成交量47.93万
今开0.7928	昨收0.7978	日振幅6.52%
总市值1,549万	流通市值1,504万	总股本1,913万
成交额37.93万	换手率2.58%	流通股本1,857万
市净率--	ROE--	每股收益0.00
52周最高--	52周最低--	市盈率--
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研究成果推进至更多临床前验证研究","url":"https://stock-news.laohu8.com/highlight/detail?id=1149943911","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1149943911?lang=zh_cn&edition=full","pubTime":"2026-04-14 19:05","pubTimestamp":1776164704,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics 宣布将把其 HT-VA 项目的关键发现推进至额外的临床前验证研究阶段。这一举措旨在进一步评估该候选疗法的有效性与安全性，为后续开发奠定基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1188422004","title":"Hoth Therapeutics：GDNF在MAFLD与肥胖模型中显著降低SREBF1并提升PPARα","url":"https://stock-news.laohu8.com/highlight/detail?id=1188422004","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1188422004?lang=zh_cn&edition=full","pubTime":"2026-04-14 05:25","pubTimestamp":1776115540,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics公司公布的研究数据显示，其关注的胶质细胞源性神经营养因子（GDNF）在代谢相关脂肪性肝病（MAFLD）与肥胖实验模型中表现出显著作用。该因子能够有效降低固醇调节元件结合转录因子1（SREBF1）的表达水平，同时促进过氧化物酶体增殖物激活受体α（PPARα）的活性提升。\n这一发现为开发针对代谢紊乱相关疾病的创新疗法提供了新的分子机制依据，突显了GDNF在调节脂质代谢通路中的潜在治疗价值。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1171005149","title":"Hoth Therapeutics公布HT-VA CRADA积极数据：GDNF重构肝脏脂肪代谢机制，关闭脂肪生成基因并激活燃脂通路，效果优于司美格鲁肽","url":"https://stock-news.laohu8.com/highlight/detail?id=1171005149","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1171005149?lang=zh_cn&edition=full","pubTime":"2026-04-14 05:25","pubTimestamp":1776115524,"startTime":"0","endTime":"0","summary":"生物制药公司Hoth Therapeutics最新发布的HT-VA合作研发协议数据取得突破性进展。研究显示，胶质细胞源性神经营养因子能够重塑肝脏脂肪代谢系统，成功抑制脂肪合成基因的表达，同时激活多条脂肪分解代谢通路。值得注意的是，该疗法在临床前研究中表现出优于糖尿病药物司美格鲁肽的代谢调节能力。\n实验数据揭示，GDNF通过调控肝脏细胞能量代谢的关键节点，实现脂肪代谢的双向调节：一方面有效阻断新生脂肪的积累途径，另一方面显著提升脂肪酸氧化效率。这种独特的作用机制为治疗代谢性疾病提供了新的方向，尤其对非酒精性脂肪肝等疾病具有潜在治疗价值。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1131915652","title":"Hoth Therapeutics预计西班牙与波兰监管审批在即 试验站点即将启动","url":"https://stock-news.laohu8.com/highlight/detail?id=1131915652","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1131915652?lang=zh_cn&edition=full","pubTime":"2026-04-01 20:17","pubTimestamp":1775045833,"startTime":"0","endTime":"0","summary":"生物制药公司Hoth Therapeutics近日透露，其针对特应性皮炎的新型疗法已向西班牙与波兰监管机构提交审批申请，预计短期内将获得通过。这意味着该公司位于两国的临床试验站点有望迅速投入运营，加速推进其创新药物的国际化布局。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1118216933","title":"匈牙利批准扩大临床试验，因HT-001中期分析达主要终点，患者第六周实现ARIGA≤1","url":"https://stock-news.laohu8.com/highlight/detail?id=1118216933","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1118216933?lang=zh_cn&edition=full","pubTime":"2026-04-01 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Therapeutics公布HT-001积极数据：EGFR疗法相关皮肤毒性患者药物暴露量提升约77%且全身吸收极低","url":"https://stock-news.laohu8.com/highlight/detail?id=1188249439","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1188249439?lang=zh_cn&edition=full","pubTime":"2026-03-24 20:14","pubTimestamp":1774354455,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics最新公布的临床研究数据显示，其针对EGFR抑制剂引发皮肤毒性的抗癌患者研发的HT-001疗法，在药代动力学、安全性及临床活性方面表现积极。数据显示，该疗法可使局部药物暴露量提升约77%，同时全身系统性吸收维持在极低水平。\n该结果印证了HT-001通过局部给药精准靶向皮肤毒性的治疗策略，在维持有效局部药物浓度的同时，最大限度降低了全身性副作用风险。这一特性对于需要长期接受EGFR靶向治疗的癌症患者具有重要临床意义。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1140710087","title":"Hoth Therapeutics公布积极雌性临床前数据，显示HT-VA在MASLD模型中恢复胆固醇水平并改善脂质代谢","url":"https://stock-news.laohu8.com/highlight/detail?id=1140710087","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1140710087?lang=zh_cn&edition=full","pubTime":"2026-03-10 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05:15","pubTimestamp":1771967741,"startTime":"0","endTime":"0","summary":"随着患者需求显著上升，Hoth Therapeutics 正通过增设新的临床研究中心，全力加快其核心候选药物 HT-001 的临床试验患者入组进程。\n这一战略举措旨在高效应对日益增长的患者参与意愿，确保试验能够按计划甚至提前推进，从而为后续的药物开发奠定坚实基础。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1120538790","title":"Hoth Therapeutics：GDNF疗法使体重增长减缓10-15%，治疗末期趋于稳定","url":"https://stock-news.laohu8.com/highlight/detail?id=1120538790","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1120538790?lang=zh_cn&edition=full","pubTime":"2026-02-10 21:33","pubTimestamp":1770730393,"startTime":"0","endTime":"0","summary":"生物制药公司Hoth Therapeutics宣布，其研发的GDNF疗法在实验研究中展现出显著效果——能够将体重增长幅度抑制10%至15%。值得注意的是，在治疗周期的最后几周，受试者的体重数据进入平台期，不再呈现明显上升趋势。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1175429669","title":"Hoth Therapeutics：匈牙利、西班牙及波兰的国别第二部分监管决定预计于2026年1月19日前公布","url":"https://stock-news.laohu8.com/highlight/detail?id=1175429669","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1175429669?lang=zh_cn&edition=full","pubTime":"2026-01-15 21:19","pubTimestamp":1768483154,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics公司宣布，针对其产品在匈牙利、西班牙和波兰的国别第二部分监管审批决定，预计将在2026年1月19日前作出。这一关键进展将直接影响该公司在欧洲市场的战略布局。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","HOTH"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1185056438","title":"Hoth Therapeutics 迎来欧盟关键监管节点，推动HT-001肿瘤试验在多国启动临床中心","url":"https://stock-news.laohu8.com/highlight/detail?id=1185056438","media":"美股速递","labels":["corporation"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1185056438?lang=zh_cn&edition=full","pubTime":"2026-01-15 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Therapeutics启动VA支持的研究，探讨新型GDNF减肥疗法针对肥胖和脂肪肝疾病","url":"https://stock-news.laohu8.com/highlight/detail?id=1109800441","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1109800441?lang=zh_cn&edition=full","pubTime":"2025-10-27 19:50","pubTimestamp":1761565811,"startTime":"0","endTime":"0","summary":"Hoth Therapeutics启动VA支持的研究，探讨新型GDNF减肥疗法针对肥胖和脂肪肝疾病","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HOTH","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1186024761","title":"Hoth 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股价大跌5.50%","url":"https://stock-news.laohu8.com/highlight/detail?id=2518222824","media":"市场透视","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2518222824?lang=zh_cn&edition=full","pubTime":"2025-03-10 21:33","pubTimestamp":1741613630,"startTime":"0","endTime":"0","summary":"北京时间2025年03月10日21时33分，Hoth Therapeutics, Inc.股票出现异动，股价大幅下跌5.50%。截至发稿，该股报1.03美元/股，成交量24.2463万股，换手率1.84%，振幅3.67%。Hoth Therapeutics, Inc.股票所在的生物技术行业中，整体跌幅为0.08%。其相关个股中，Checkpoint Therapeutics, Inc.、Trevi Therapeutics, Inc.、Biodexa Pharmaceuticals Plc涨幅较大，Biodexa Pharmaceuticals Plc、Scisparc Ltd.、Dogwood Therapeutics, Inc.较为活跃，换手率分别为2087.41%、410.08%、63.40%，振幅较大的相关个股有Akero Therapeutics, Inc.、Xencor, Inc.、Seer, Inc.，振幅分别为100.05%、99.13%、98.72%。Hoth Therapeutics, Inc.公司简介：Hoth Therapeutics Inc是一家处于发展阶段的生物制药公司。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN20250310213350a26a257f&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, 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Therapeutics, Inc.股票所在的生物技术行业中，整体涨幅为0.20%。其相关个股中，Chimerix, Inc.、Klotho Neurosciences Inc C/Wts 21/06/2029 、Silexion Therapeutics Corp涨幅较大，Silexion Therapeutics Corp、Tc Biopharm  Plc、Zyversa Therapeutics, Inc.较为活跃，换手率分别为355.98%、258.41%、187.27%，振幅较大的相关个股有Aditxt, Inc.、Silexion Therapeutics Corp、Invivyd, Inc.，振幅分别为23.90%、15.31%、13.32%。Hoth Therapeutics, Inc.公司简介：Hoth Therapeutics Inc是一家处于发展阶段的生物制药公司。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN20250305223300963adc99&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, 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