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09688 再鼎医药
已收盘 04-22 16:08:12
24.400
+1.600
+7.02%
最高
24.850
最低
23.200
成交量
1,301万
今开
23.300
昨收
22.800
日振幅
7.24%
总市值
268.64亿
流通市值
268.64亿
总股本
11.01亿
成交额
3.16亿
换手率
1.18%
流通股本
11.01亿
市净率
4.12
ROE
-31.41%
每股收益
-2.02
52周最高
32.500
52周最低
10.560
市盈率
-12.10
股息
0.00
股息收益率
0.00
ROA
-15.87%
分时
五日
日K
周K
月K
北京优虎网络科技有限公司
免责声明:香港交易所资讯服务有限公司、其控股公司及/或该等控股公司的任何附属公司均竭力确保所提供信息的准确和可靠度,但不能保证其绝对准确和可靠,且亦不会承担因任何不准确或遗漏而引起的任何损失或损害的责任(不管是否侵权法下的责任或合约责任又或其它责任)
资讯
新帖
简况
再鼎医药(ZLAB)盘前涨超7% 瑞普替尼新适应症上市申请获受理
金吾财讯 · 40分钟前
再鼎医药(ZLAB)盘前涨超7% 瑞普替尼新适应症上市申请获受理
再鼎医药04月22日主力净流入1772万元 散户资金抛售
市场透视 · 08:16
再鼎医药04月22日主力净流入1772万元 散户资金抛售
港股异动 | 再鼎医药(09688)涨超7% 瑞普替尼新适应症上市申请获受理
智通财经 · 07:34
港股异动 | 再鼎医药(09688)涨超7% 瑞普替尼新适应症上市申请获受理
港股医药逆势走强 港股医药ETF涨超3% 冲击四连涨
东方财富证券 · 03:10
港股医药逆势走强 港股医药ETF涨超3% 冲击四连涨
异动解读 | 再鼎医药盘中大涨7.46%,南向资金持续加仓
异动解读 · 02:12
异动解读 | 再鼎医药盘中大涨7.46%,南向资金持续加仓
再鼎医药04月17日遭主力抛售205万元
市场透视 · 04-17
再鼎医药04月17日遭主力抛售205万元
中金:维持再鼎医药(09688)跑赢行业评级 目标价34.41港元
智通财经 · 04-17
中金:维持再鼎医药(09688)跑赢行业评级 目标价34.41港元
高盛研报:重症肌无力市场格局重塑?强烈看好再鼎医药艾加莫德绝对竞争力
智通财经网 · 04-16
高盛研报:重症肌无力市场格局重塑?强烈看好再鼎医药艾加莫德绝对竞争力
再鼎医药04月16日主力净流出1291万元 散户资金买入
市场透视 · 04-16
再鼎医药04月16日主力净流出1291万元 散户资金买入
再鼎医药盘中异动 早盘股价大跌5.17%
市场透视 · 04-16
再鼎医药盘中异动 早盘股价大跌5.17%
异动解读 | 再鼎医药盘中大涨5.34%,南向资金持续加仓或成推手
异动解读 · 04-15
异动解读 | 再鼎医药盘中大涨5.34%,南向资金持续加仓或成推手
异动解读 | 再鼎医药盘中大涨5.34%,南向资金大幅增持
异动解读 · 04-15
异动解读 | 再鼎医药盘中大涨5.34%,南向资金大幅增持
美股异动 | 再鼎医药(ZLAB.US)涨逾8% FDA批准艾加莫德预充式皮下注射剂型
智通财经 · 04-14
美股异动 | 再鼎医药(ZLAB.US)涨逾8% FDA批准艾加莫德预充式皮下注射剂型
再鼎医药盘前续涨超6% 将于今年递交艾加莫德预充式皮下注射剂型上市申请
格隆汇 · 04-14
再鼎医药盘前续涨超6% 将于今年递交艾加莫德预充式皮下注射剂型上市申请
【券商聚焦】德邦证券:再鼎医药艾加莫德优势明显,维持“买入”评级
金吾财讯 · 04-14
【券商聚焦】德邦证券:再鼎医药艾加莫德优势明显,维持“买入”评级
港股异动 | 医药股涨幅居前 再鼎医药(09688)涨近15% 和铂医药-B(02142)涨超10%
智通财经 · 04-14
港股异动 | 医药股涨幅居前 再鼎医药(09688)涨近15% 和铂医药-B(02142)涨超10%
港股生物医药板块盘初走强,再鼎医药涨超12%,君实生物涨超5%,百济神州、药明康德等跟涨。
金融界 · 04-14
港股生物医药板块盘初走强,再鼎医药涨超12%,君实生物涨超5%,百济神州、药明康德等跟涨。
港股生物医药板块盘初走强,再鼎医药(09688.HK)涨超12%,君实生物(01877.HK)涨超5%,百济神州(061
美港电讯 · 04-14
港股生物医药板块盘初走强,再鼎医药(09688.HK)涨超12%,君实生物(01877.HK)涨超5%,百济神州(061
【港股医药股多数走强 再鼎医药涨超13%】截至发稿,再鼎医药(09688.HK)涨13.51%、来凯医药-B(02105.HK)涨10.34%、基石药业-B(02616.HK)涨6.28%、腾盛博药-B(02137.HK)涨6.17%、药明合联(02268.HK)涨5.94%。
金融界 · 04-14
【港股医药股多数走强 再鼎医药涨超13%】截至发稿,再鼎医药(09688.HK)涨13.51%、来凯医药-B(02105.HK)涨10.34%、基石药业-B(02616.HK)涨6.28%、腾盛博药-B(02137.HK)涨6.17%、药明合联(02268.HK)涨5.94%。
港股生物医药股大幅上涨,永泰生物-B涨超15%
老虎资讯综合 · 04-14
港股生物医药股大幅上涨,永泰生物-B涨超15%
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公司概况
公司名称:
再鼎医药
所属市场:
SEHK
上市日期:
--
主营业务:
再鼎医药有限公司是一家主要从事生物制药的控股公司。该公司致力于通过产品的发现、开发和商业化解决肿瘤、自身免疫疾病、感染性疾病和中枢神经系统疾病领域未被满足的医疗需求。该公司拥有从发现阶段到临床项目后期的一系列专利候选药物。其中包括“则乐”、“OPTUNE”、“擎乐”、“纽再乐”及“卫伟迦”等。
发行价格:
--
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15:34","pubTimestamp":1745307273,"startTime":"0","endTime":"0","summary":"智通财经APP获悉,再鼎医药涨超7%,截至发稿,涨7.02%,报24.4港元,成交额2.79亿港元。另外,公司合作伙伴argenx近日宣布,艾加莫德预充针皮下注射剂型获美国FDA批准上市。据悉,目前在国内,艾加莫德已有静脉输注和皮下注射2种给药方式。再鼎医药将于2025年在国内递交艾加莫德预充式皮下注射剂型的上市申请。","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://www.zhitongcaijing.com/content/detail/1282177.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease,movement","news_rank":0,"length":0,"strategy_id":0,"source":"stock_zhitongcaijing","symbols":["BK1574","BK4139","BK4588","BK4585","ZLAB","BK4548","BK1161","BK4526","BK1588","09688","LU2488822045.USD","BK4531"],"gpt_icon":0},{"id":"2529391901","title":"港股医药逆势走强 港股医药ETF涨超3% 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| 再鼎医药盘中大涨7.46%,南向资金持续加仓","url":"https://stock-news.laohu8.com/highlight/detail?id=1167239425","media":"异动解读","labels":["movement"],"top":1,"itemType":null,"share":"https://www.laohu8.com/m/news/1167239425?lang=zh_cn&edition=full","pubTime":"2025-04-22 10:12","pubTimestamp":1745287947,"startTime":"0","endTime":"0","summary":"再鼎医药今日盘中大涨7.46%,引发市场关注。分析人士认为,这一涨幅可能与南向资金持续加仓有关。截至当日收盘,港股通共持有再鼎医药1.99亿股,占流通股18.10%。值得注意的是,再鼎医药近5个交易日上涨4.59%,期间港股通累计增持2105.94万股;虽然近20个交易日下跌23.62%,但港股通仍累计增持4455.90万股,显示出南向资金对该股的持续看好。然而,投资者仍需警惕市场风险,密切关注公司基本面变化和行业动态。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"异动解读 | 再鼎医药盘中大涨7.46%,南向资金持续加仓","news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_cn","symbols":["09688"],"gpt_icon":0},{"id":"2528892760","title":"再鼎医药04月17日遭主力抛售205万元","url":"https://stock-news.laohu8.com/highlight/detail?id=2528892760","media":"市场透视","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2528892760?lang=zh_cn&edition=full","pubTime":"2025-04-17 16:15","pubTimestamp":1744877758,"startTime":"0","endTime":"0","summary":"04月17日, 再鼎医药股价跌1.30%,报收22.80元,成交金额2.34亿元,换手率0.93%,振幅5.19%,量比0.66。再鼎医药今日主力资金净流出205万元,上一交易日主力净流出1291万元。该股近5个交易日上涨5.73%,主力资金累计净流入1.48亿元,其中1个交易日为股价下跌时净流入;近20日主力资金累计净流入2.87亿元,其中净流入天数为15日。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN20250417170254a45c4321&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description 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09:15","pubTimestamp":1744852527,"startTime":"0","endTime":"0","summary":"智通财经APP获悉,中金发布研报称,维持再鼎医药2025年和2026年盈利预测不变。该行维持跑赢行业评级,基于DCF模型,该行维持H/US股目标价34.41港元/44.24美元不变。4月11日,公司合作伙伴argenx宣布艾加莫德预充针皮下注射剂型获美国FDA批准上市。目前在国内,艾加莫德已有静脉输注和皮下注射2种给药方式,公司将于2025年在国内递交艾加莫德预充式皮下注射剂型的上市申请。","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://www.zhitongcaijing.com/content/detail/1279879.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"stock_zhitongcaijing","symbols":["ZLAB","09688"],"gpt_icon":1},{"id":"2527970172","title":"高盛研报:重症肌无力市场格局重塑?强烈看好再鼎医药艾加莫德绝对竞争力","url":"https://stock-news.laohu8.com/highlight/detail?id=2527970172","media":"智通财经网","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2527970172?lang=zh_cn&edition=full","pubTime":"2025-04-16 18:53","pubTimestamp":1744800794,"startTime":"0","endTime":"0","summary":"艾加莫德的快速起效特性,使其在急性和难治性患者中尤为受欢迎。这可能成为未来竞争格局中推动艾加莫德市场份额扩大的重要因素。这表明艾加莫德可以作为一种可靠的维持治疗方案。“研究外”要素不容忽视高盛的报告指出,随着重症肌无力药物选择的愈加丰富,除了临床数据外,还有诸多“临床研究外”因素可能影响竞争格局。高盛认为,这一时间差为艾加莫德提供了至少两年的市场先发优势。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN202504161857109739d59c&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, .wx-sou","directOrigin":true},"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN202504161857109739d59c&s=b","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tencent","symbols":["BK1588","09688","LU2488822045.USD","BK1574","BK1161"],"gpt_icon":0},{"id":"2527298983","title":"再鼎医药04月16日主力净流出1291万元 散户资金买入","url":"https://stock-news.laohu8.com/highlight/detail?id=2527298983","media":"市场透视","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2527298983?lang=zh_cn&edition=full","pubTime":"2025-04-16 16:15","pubTimestamp":1744791321,"startTime":"0","endTime":"0","summary":"04月16日, 再鼎医药股价跌4.55%,报收23.10元,成交金额2.61亿元,换手率1.03%,振幅6.61%,量比0.73。再鼎医药今日主力资金净流出1291万元,上一交易日主力净流入834万元。该股近5个交易日上涨3.10%,主力资金累计净流入1.81亿元,其中2个交易日为股价下跌时净流入;近20日主力资金累计净流入2.93亿元,其中净流入天数为16日。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN20250416173240a6bc6331&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, .wx-sou","directOrigin":true},"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN20250416173240a6bc6331&s=b","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tencent","symbols":["09688","BK1574","BK1161","BK1588","LU2488822045.USD"],"gpt_icon":0},{"id":"2527839932","title":"再鼎医药盘中异动 早盘股价大跌5.17%","url":"https://stock-news.laohu8.com/highlight/detail?id=2527839932","media":"市场透视","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2527839932?lang=zh_cn&edition=full","pubTime":"2025-04-16 10:19","pubTimestamp":1744769965,"startTime":"0","endTime":"0","summary":"2025年04月16日早盘10时19分,再鼎医药股票出现异动,股价急速跳水5.17%。截至发稿,该股报22.950港元/股,成交量317.596万股,换手率0.29%,振幅3.51%。再鼎医药股票所在的生物技术行业中,整体跌幅为2.30%。其相关个股中,复宏汉霖、贝康医疗-B、荃信生物-B涨幅较大,振幅较大的相关个股有歌礼制药-B、科伦博泰生物-B、荣昌生物,振幅分别为9.44%、7.99%、7.78%。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tencent","url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2025041610192597394a6d&s=b","rn_cache_url":null,"customStyle":"body{padding-top:10px;}#news_title{font-weight:bold;#titleStyle#;}#news_description span{font-size:12px;#descriptionStyle#;}.footer-note{#statement#}","selectors":".mod-LoadTzbdNews, body","filters":".relate-stock, .hot-list, .recom-box, .wx-sou","directOrigin":true},"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://gu.qq.com/resources/shy/news/detail-v2/index.html#/?id=nesSN2025041610192597394a6d&s=b","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tencent","symbols":["BK1588","09688","LU2488822045.USD","BK1574","BK1161"],"gpt_icon":0},{"id":"1126441949","title":"异动解读 | 再鼎医药盘中大涨5.34%,南向资金持续加仓或成推手","url":"https://stock-news.laohu8.com/highlight/detail?id=1126441949","media":"异动解读","labels":["movement"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1126441949?lang=zh_cn&edition=full","pubTime":"2025-04-15 10:10","pubTimestamp":1744683030,"startTime":"0","endTime":"0","summary":"再鼎医药今日盘中大涨5.34%,引发市场关注。这一涨势很可能与南向资金的持续加仓有关。截至当日收盘,港股通共持有再鼎医药1.8685亿股,占流通股的16.97%。值得注意的是,再鼎医药近5个交易日已上涨12.73%,同期港股通累计增持1678.81万股,显示出投资者对该股的持续看好。南向资金的增持往往被视为看好公司前景的信号,可能吸引更多投资者跟随买入。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_cn","symbols":["09688"],"gpt_icon":0},{"id":"1149995493","title":"异动解读 | 再鼎医药盘中大涨5.34%,南向资金大幅增持","url":"https://stock-news.laohu8.com/highlight/detail?id=1149995493","media":"异动解读","labels":["movement"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/1149995493?lang=zh_cn&edition=full","pubTime":"2025-04-15 10:10","pubTimestamp":1744683029,"startTime":"0","endTime":"0","summary":"再鼎医药今日盘中大涨5.34%,引起市场广泛关注。该股在早盘交易中表现突出,成为港股市场中的亮点之一。据悉,在4月14日,南向资金大幅增持再鼎医药474.18万股。截至当日收盘,港股通共持有再鼎医药1.8685亿股,占公司流通股的16.97%。数据显示,该股在近5个交易日内累计上涨12.73%,期间港股通累计增持1678.81万股。然而,从更长期来看,再鼎医药在近20个交易日内下跌16.61%,但港股通仍然选择逆势增持,累计增持量达到3305.81万股。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_cn","symbols":["09688"],"gpt_icon":0},{"id":"2527768191","title":"美股异动 | 再鼎医药(ZLAB.US)涨逾8% FDA批准艾加莫德预充式皮下注射剂型","url":"https://stock-news.laohu8.com/highlight/detail?id=2527768191","media":"智通财经","labels":["productRelease","movement"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2527768191?lang=zh_cn&edition=full","pubTime":"2025-04-14 22:59","pubTimestamp":1744642769,"startTime":"0","endTime":"0","summary":"智通财经APP获悉,周一,再鼎医药(ZLAB.US)盘中一度涨超13%,截至发稿,涨逾8%,报32.09美元。消息面上,4月11日,再鼎医药合作伙伴argenx公司宣布,美国食品药品监督管理局(FDA)已正式批准了艾加莫德预充式皮下注射剂型,用于治疗乙酰胆碱受体(AChR)抗体阳性的全身型重症肌无力(gMG)成人患者和慢性炎性脱髓鞘性多发性神经根神经病(CIDP)成人患者。再鼎医药表示,将于2025年在国内递交艾加莫德预充式皮下注射剂型的上市申请。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"http://www.zhitongcaijing.com/content/detail/1278555.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"美股异动 | 再鼎医药(ZLAB.US)涨逾8% FDA批准艾加莫德预充式皮下注射剂型","news_tag":"productRelease,movement","news_rank":0,"length":0,"strategy_id":0,"source":"stock_zhitongcaijing","symbols":["BK4588","BK4548","ZLAB","BK4526","09688","BK4139","BK1574","BK1161","BK1588","BK4585","BK4531","LU2488822045.USD"],"gpt_icon":0},{"id":"2527188984","title":"再鼎医药盘前续涨超6% 将于今年递交艾加莫德预充式皮下注射剂型上市申请","url":"https://stock-news.laohu8.com/highlight/detail?id=2527188984","media":"格隆汇","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2527188984?lang=zh_cn&edition=full","pubTime":"2025-04-14 16:22","pubTimestamp":1744618954,"startTime":"0","endTime":"0","summary":"再鼎医药(ZLAB.US)盘前续涨超6%,报31.32美元。该股上周五大幅收涨超21.4%。消息面上,4月11日,再鼎医药合作伙伴argenx公司宣布,美国食品药品监督管理局(FDA)已正式批准了艾加莫德预充式皮下注射剂型,用于治疗乙酰胆碱受体(AChR)抗体阳性的全身型重症肌无力(gMG)成人患者和慢性炎性脱髓鞘性多发性神经根神经病(CIDP)成人患者。再鼎医药表示,将于2025年在国内递交艾加莫德预充式皮下注射剂型的上市申请。\n\n\r\n 责任编辑:小讯","market":"sh","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://usstock.jrj.com.cn/2025/04/14162249519024.shtml","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"jinrongjie_highlight","symbols":["BK4139","09688","BK1161","BK1574","BK4588","BK4526","BK4531","BK4548","ZLAB","BK4585","BK1588","LU2488822045.USD"],"gpt_icon":0},{"id":"2527921945","title":"【券商聚焦】德邦证券:再鼎医药艾加莫德优势明显,维持“买入”评级","url":"https://stock-news.laohu8.com/highlight/detail?id=2527921945","media":"金吾财讯","labels":[],"top":-1,"itemType":null,"share":"https://www.laohu8.com/m/news/2527921945?lang=zh_cn&edition=full","pubTime":"2025-04-14 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